 Th2 Cells
"Th2 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subset of helper-inducer T-lymphocytes which synthesize and secrete the INTERLEUKINS IL-4; IL-5; IL-6; and IL-10. These cytokines influence B-cell development and antibody production as well as augmenting humoral responses.
| Descriptor ID |
D018418
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| MeSH Number(s) |
A11.118.637.555.567.550.500.400.905 A11.118.637.555.567.569.200.400.905 A11.118.637.555.567.569.500.400.905 A15.145.229.637.555.567.550.500.400.750 A15.145.229.637.555.567.569.200.400.750 A15.145.229.637.555.567.569.500.400.750 A15.382.490.555.567.550.500.400.905 A15.382.490.555.567.569.200.400.905 A15.382.490.555.567.569.500.400.905
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| Concept/Terms |
Th2 Cells- Th2 Cells
- Cell, Th2
- Cells, Th2
- Th2 Cell
- T Helper 2 Cells
- TH-2 Cells
- Cell, TH-2
- Cells, TH-2
- TH 2 Cells
- TH-2 Cell
- T Helper2 Cells
- Cell, T Helper2
- Cells, T Helper2
- T Helper2 Cell
- Type-2 Helper T Cells
- Type 2 Helper T Cells
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Below are MeSH descriptors whose meaning is more general than "Th2 Cells".
- Anatomy [A]
- Cells [A11]
- Blood Cells [A11.118]
- Leukocytes [A11.118.637]
- Leukocytes, Mononuclear [A11.118.637.555]
- Lymphocytes [A11.118.637.555.567]
- Lymphocyte Subsets [A11.118.637.555.567.550]
- T-Lymphocyte Subsets [A11.118.637.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.550.500.400]
- Th2 Cells [A11.118.637.555.567.550.500.400.905]
- T-Lymphocytes [A11.118.637.555.567.569]
- CD4-Positive T-Lymphocytes [A11.118.637.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.200.400]
- Th2 Cells [A11.118.637.555.567.569.200.400.905]
- T-Lymphocyte Subsets [A11.118.637.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.500.400]
- Th2 Cells [A11.118.637.555.567.569.500.400.905]
- Hemic and Immune Systems [A15]
- Blood [A15.145]
- Blood Cells [A15.145.229]
- Leukocytes [A15.145.229.637]
- Leukocytes, Mononuclear [A15.145.229.637.555]
- Lymphocytes [A15.145.229.637.555.567]
- Lymphocyte Subsets [A15.145.229.637.555.567.550]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.550.500.400]
- Th2 Cells [A15.145.229.637.555.567.550.500.400.750]
- T-Lymphocytes [A15.145.229.637.555.567.569]
- CD4-Positive T-Lymphocytes [A15.145.229.637.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.200.400]
- Th2 Cells [A15.145.229.637.555.567.569.200.400.750]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.500.400]
- Th2 Cells [A15.145.229.637.555.567.569.500.400.750]
- Immune System [A15.382]
- Leukocytes [A15.382.490]
- Leukocytes, Mononuclear [A15.382.490.555]
- Lymphocytes [A15.382.490.555.567]
- Lymphocyte Subsets [A15.382.490.555.567.550]
- T-Lymphocyte Subsets [A15.382.490.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.550.500.400]
- Th2 Cells [A15.382.490.555.567.550.500.400.905]
- T-Lymphocytes [A15.382.490.555.567.569]
- CD4-Positive T-Lymphocytes [A15.382.490.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.200.400]
- Th2 Cells [A15.382.490.555.567.569.200.400.905]
- T-Lymphocyte Subsets [A15.382.490.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.500.400]
- Th2 Cells [A15.382.490.555.567.569.500.400.905]
Below are MeSH descriptors whose meaning is more specific than "Th2 Cells".
This graph shows the total number of publications written about "Th2 Cells" by people in this website by year, and whether "Th2 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 1 | 2 | | 1998 | 0 | 1 | 1 | | 2000 | 2 | 1 | 3 | | 2001 | 1 | 0 | 1 | | 2002 | 2 | 0 | 2 | | 2003 | 5 | 4 | 9 | | 2004 | 8 | 2 | 10 | | 2005 | 2 | 3 | 5 | | 2006 | 4 | 5 | 9 | | 2007 | 3 | 1 | 4 | | 2008 | 4 | 3 | 7 | | 2009 | 1 | 4 | 5 | | 2010 | 5 | 2 | 7 | | 2011 | 2 | 6 | 8 | | 2012 | 4 | 4 | 8 | | 2013 | 2 | 5 | 7 | | 2014 | 5 | 1 | 6 | | 2015 | 5 | 0 | 5 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 3 | 4 | | 2018 | 0 | 3 | 3 | | 2019 | 3 | 1 | 4 | | 2020 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Th2 Cells" by people in Profiles.
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Qian Q, Chowdhury BP, Sun Z, Lenberg J, Alam R, Vivier E, Gorska MM. Maternal diesel particle exposure promotes offspring asthma through NK cell-derived granzyme B. J Clin Invest. 2020 08 03; 130(8):4133-4151.
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Wang M, Strand MJ, Lanser BJ, Santos C, Bendelja K, Fish J, Esterl EA, Ashino S, Abbott JK, Knight V, Gelfand EW. Expression and activation of the steroidogenic enzyme CYP11A1 is associated with IL-13 production in T cells from peanut allergic children. PLoS One. 2020; 15(6):e0233563.
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Boorgula MP, Taub MA, Rafaels N, Daya M, Campbell M, Chavan S, Shetty A, Cheadle C, Barkataki S, Fan J, David G, Beaty TH, Ruczinski I, Hanifin J, Schneider LC, Gallo RL, Paller AS, Beck LA, Leung DY, Mathias RA, Barnes KC. Replicated methylation changes associated with eczema herpeticum and allergic response. Clin Epigenetics. 2019 08 23; 11(1):122.
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Kumar R, Mickael C, Kassa B, Sanders L, Koyanagi D, Hernandez-Saavedra D, Freeman S, Morales-Cano D, Cogolludo A, McKee AS, Fontenot AP, Butrous G, Tuder RM, Graham BB. Th2 CD4+ T Cells Are Necessary and Sufficient for Schistosoma-Pulmonary Hypertension. J Am Heart Assoc. 2019 08 06; 8(15):e013111.
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Zhou X, Kinlough CL, Hughey RP, Jin M, Inoue H, Etling E, Modena BD, Kaminski N, Bleecker ER, Meyers DA, Jarjour NN, Trudeau JB, Holguin F, Ray A, Wenzel SE. Sialylation of MUC4ß N-glycans by ST6GAL1 orchestrates human airway epithelial cell differentiation associated with type-2 inflammation. JCI Insight. 2019 03 07; 4(5).
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Mickael CS, Graham BB. The Role of Type 2 Inflammation in Schistosoma-Induced Pulmonary Hypertension. Front Immunol. 2019; 10:27.
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Taitano SH, van der Vlugt LEPM, Shea MM, Yang J, Lukacs NW, Lundy SK. Differential Influence on Regulatory B Cells by TH2 Cytokines Affects Protection in Allergic Airway Disease. J Immunol. 2018 10 01; 201(7):1865-1874.
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Davidson EJ, Yang IV. Role of epigenetics in the development of childhood asthma. Curr Opin Allergy Clin Immunol. 2018 04; 18(2):132-138.
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Berdyshev E, Goleva E, Bronova I, Dyjack N, Rios C, Jung J, Taylor P, Jeong M, Hall CF, Richers BN, Norquest KA, Zheng T, Seibold MA, Leung DY. Lipid abnormalities in atopic skin are driven by type 2 cytokines. JCI Insight. 2018 02 22; 3(4).
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Wright BL, Nguyen N, Shim KP, Masterson JC, Jacobsen EA, Ochkur SI, Lee JJ, Furuta GT. Increased GATA-3 and T-bet expression in eosinophilic esophagitis versus gastroesophageal reflux disease. J Allergy Clin Immunol. 2018 05; 141(5):1919-1921.e5.
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