 Th2 Cells
"Th2 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subset of helper-inducer T-lymphocytes which synthesize and secrete the INTERLEUKINS IL-4; IL-5; IL-6; and IL-10. These cytokines influence B-cell development and antibody production as well as augmenting humoral responses.
| Descriptor ID |
D018418
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| MeSH Number(s) |
A11.118.637.555.567.550.500.400.905 A11.118.637.555.567.569.200.400.905 A11.118.637.555.567.569.500.400.905 A15.145.229.637.555.567.550.500.400.750 A15.145.229.637.555.567.569.200.400.750 A15.145.229.637.555.567.569.500.400.750 A15.382.490.555.567.550.500.400.905 A15.382.490.555.567.569.200.400.905 A15.382.490.555.567.569.500.400.905
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| Concept/Terms |
Th2 Cells- Th2 Cells
- Cell, Th2
- Cells, Th2
- Th2 Cell
- T Helper 2 Cells
- TH-2 Cells
- Cell, TH-2
- Cells, TH-2
- TH 2 Cells
- TH-2 Cell
- T Helper2 Cells
- Cell, T Helper2
- Cells, T Helper2
- T Helper2 Cell
- Type-2 Helper T Cells
- Type 2 Helper T Cells
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Below are MeSH descriptors whose meaning is more general than "Th2 Cells".
- Anatomy [A]
- Cells [A11]
- Blood Cells [A11.118]
- Leukocytes [A11.118.637]
- Leukocytes, Mononuclear [A11.118.637.555]
- Lymphocytes [A11.118.637.555.567]
- Lymphocyte Subsets [A11.118.637.555.567.550]
- T-Lymphocyte Subsets [A11.118.637.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.550.500.400]
- Th2 Cells [A11.118.637.555.567.550.500.400.905]
- T-Lymphocytes [A11.118.637.555.567.569]
- CD4-Positive T-Lymphocytes [A11.118.637.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.200.400]
- Th2 Cells [A11.118.637.555.567.569.200.400.905]
- T-Lymphocyte Subsets [A11.118.637.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.500.400]
- Th2 Cells [A11.118.637.555.567.569.500.400.905]
- Hemic and Immune Systems [A15]
- Blood [A15.145]
- Blood Cells [A15.145.229]
- Leukocytes [A15.145.229.637]
- Leukocytes, Mononuclear [A15.145.229.637.555]
- Lymphocytes [A15.145.229.637.555.567]
- Lymphocyte Subsets [A15.145.229.637.555.567.550]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.550.500.400]
- Th2 Cells [A15.145.229.637.555.567.550.500.400.750]
- T-Lymphocytes [A15.145.229.637.555.567.569]
- CD4-Positive T-Lymphocytes [A15.145.229.637.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.200.400]
- Th2 Cells [A15.145.229.637.555.567.569.200.400.750]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.500.400]
- Th2 Cells [A15.145.229.637.555.567.569.500.400.750]
- Immune System [A15.382]
- Leukocytes [A15.382.490]
- Leukocytes, Mononuclear [A15.382.490.555]
- Lymphocytes [A15.382.490.555.567]
- Lymphocyte Subsets [A15.382.490.555.567.550]
- T-Lymphocyte Subsets [A15.382.490.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.550.500.400]
- Th2 Cells [A15.382.490.555.567.550.500.400.905]
- T-Lymphocytes [A15.382.490.555.567.569]
- CD4-Positive T-Lymphocytes [A15.382.490.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.200.400]
- Th2 Cells [A15.382.490.555.567.569.200.400.905]
- T-Lymphocyte Subsets [A15.382.490.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.500.400]
- Th2 Cells [A15.382.490.555.567.569.500.400.905]
Below are MeSH descriptors whose meaning is more specific than "Th2 Cells".
This graph shows the total number of publications written about "Th2 Cells" by people in this website by year, and whether "Th2 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 1 | 2 | | 1998 | 0 | 1 | 1 | | 2000 | 2 | 1 | 3 | | 2001 | 1 | 0 | 1 | | 2002 | 2 | 0 | 2 | | 2003 | 4 | 4 | 8 | | 2004 | 7 | 1 | 8 | | 2005 | 1 | 2 | 3 | | 2006 | 3 | 3 | 6 | | 2007 | 3 | 2 | 5 | | 2008 | 3 | 1 | 4 | | 2009 | 0 | 2 | 2 | | 2010 | 6 | 1 | 7 | | 2011 | 2 | 2 | 4 | | 2012 | 3 | 3 | 6 | | 2013 | 1 | 4 | 5 | | 2014 | 5 | 1 | 6 | | 2015 | 3 | 0 | 3 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 3 | 3 | | 2019 | 4 | 2 | 6 | | 2020 | 1 | 2 | 3 | | 2021 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Th2 Cells" by people in Profiles.
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Verma M, Verma D, Alam R. Role of type-2 innate lymphoid cells (ILC2s) in type-2 asthma. Curr Opin Allergy Clin Immunol. 2022 02 01; 22(1):29-35.
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Schröder A, Lunding LP, Zissler UM, Vock C, Webering S, Ehlers JC, Orinska Z, Chaker A, Schmidt-Weber CB, Lang NJ, Schiller HB, Mall MA, Fehrenbach H, Dinarello CA, Wegmann M. IL-37 regulates allergic inflammation by counterbalancing pro-inflammatory IL-1 and IL-33. Allergy. 2022 03; 77(3):856-869.
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Qian Q, Chowdhury BP, Sun Z, Lenberg J, Alam R, Vivier E, Gorska MM. Maternal diesel particle exposure promotes offspring asthma through NK cell-derived granzyme B. J Clin Invest. 2020 08 03; 130(8):4133-4151.
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Wang M, Strand MJ, Lanser BJ, Santos C, Bendelja K, Fish J, Esterl EA, Ashino S, Abbott JK, Knight V, Gelfand EW. Expression and activation of the steroidogenic enzyme CYP11A1 is associated with IL-13 production in T cells from peanut allergic children. PLoS One. 2020; 15(6):e0233563.
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Durack J, Christian LS, Nariya S, Gonzalez J, Bhakta NR, Ansel KM, Beigelman A, Castro M, Dyer AM, Israel E, Kraft M, Martin RJ, Mauger DT, Peters SP, Rosenberg SR, Sorkness CA, Wechsler ME, Wenzel SE, White SR, Lynch SV, Boushey HA, Huang YJ. Distinct associations of sputum and oral microbiota with atopic, immunologic, and clinical features in mild asthma. J Allergy Clin Immunol. 2020 11; 146(5):1016-1026.
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Liu S, Sirohi K, Verma M, McKay J, Michalec L, Sripada A, Danhorn T, Rollins D, Good J, Gorska MM, Martin RJ, Alam R. Optimal identification of human conventional and nonconventional (CRTH2-IL7Ra-) ILC2s using additional surface markers. J Allergy Clin Immunol. 2020 08; 146(2):390-405.
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Boorgula MP, Taub MA, Rafaels N, Daya M, Campbell M, Chavan S, Shetty A, Cheadle C, Barkataki S, Fan J, David G, Beaty TH, Ruczinski I, Hanifin J, Schneider LC, Gallo RL, Paller AS, Beck LA, Leung DY, Mathias RA, Barnes KC. Replicated methylation changes associated with eczema herpeticum and allergic response. Clin Epigenetics. 2019 08 23; 11(1):122.
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Itoh Y, Golden LC, Itoh N, Matsukawa MA, Ren E, Tse V, Arnold AP, Voskuhl RR. The X-linked histone demethylase Kdm6a in CD4+ T lymphocytes modulates autoimmunity. J Clin Invest. 2019 08 12; 129(9):3852-3863.
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Kumar R, Mickael C, Kassa B, Sanders L, Koyanagi D, Hernandez-Saavedra D, Freeman S, Morales-Cano D, Cogolludo A, McKee AS, Fontenot AP, Butrous G, Tuder RM, Graham BB. Th2 CD4+ T Cells Are Necessary and Sufficient for Schistosoma-Pulmonary Hypertension. J Am Heart Assoc. 2019 08 06; 8(15):e013111.
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Dakhama A, Al Mubarak R, Pavelka N, Voelker D, Seibold M, Ledford JG, Kraft M, Li L, Chu HW. Tollip Inhibits ST2 Signaling in Airway Epithelial Cells Exposed to Type 2 Cytokines and Rhinovirus. J Innate Immun. 2020; 12(1):103-115.
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