 Codon, Nonsense
"Codon, Nonsense" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An amino acid-specifying codon that has been converted to a stop codon (CODON, TERMINATOR) by mutation. Its occurance is abnormal causing premature termination of protein translation and results in production of truncated and non-functional proteins. A nonsense mutation is one that converts an amino acid-specific codon to a stop codon.
| Descriptor ID |
D018389
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| MeSH Number(s) |
D13.444.735.544.355.250.235 G05.360.335.355.250.235 G05.365.590.195
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| Concept/Terms |
Codon, Nonsense- Codon, Nonsense
- Premature Termination Codon
- Codon, Premature Termination
- Codons, Premature Termination
- Premature Termination Codons
- Termination Codon, Premature
- Termination Codons, Premature
- Premature Stop Codon
- Codon, Premature Stop
- Codons, Premature Stop
- Premature Stop Codons
- Stop Codon, Premature
- Stop Codons, Premature
- Nonsense Codon
- Codons, Nonsense
- Nonsense Codons
- Codon, Termination, Premature
Mutation, Nonsense- Mutation, Nonsense
- Mutations, Nonsense
- Nonsense Mutations
- Nonsense Mutation
Ochre Nonsense Codon- Ochre Nonsense Codon
- Codon, Ochre Nonsense
- Codons, Ochre Nonsense
- Nonsense Codon, Ochre
- Nonsense Codons, Ochre
- Ochre Nonsense Codons
Ochre Nonsense Mutation- Ochre Nonsense Mutation
- Mutation, Ochre Nonsense
- Mutations, Ochre Nonsense
- Nonsense Mutation, Ochre
- Nonsense Mutations, Ochre
- Ochre Nonsense Mutations
Amber Nonsense Mutation- Amber Nonsense Mutation
- Amber Nonsense Mutations
- Mutation, Amber Nonsense
- Mutations, Amber Nonsense
- Nonsense Mutation, Amber
- Nonsense Mutations, Amber
Opal Nonsense Mutation- Opal Nonsense Mutation
- Mutation, Opal Nonsense
- Mutations, Opal Nonsense
- Nonsense Mutation, Opal
- Nonsense Mutations, Opal
- Opal Nonsense Mutations
Amber Nonsense Codon- Amber Nonsense Codon
- Amber Nonsense Codons
- Codon, Amber Nonsense
- Codons, Amber Nonsense
- Nonsense Codons, Amber
- Nonsense Codon, Amber
Codon, Unassigned- Codon, Unassigned
- Codons, Unassigned
- Unassigned Codons
- Unassigned Codon
Opal Nonsense Codon- Opal Nonsense Codon
- Codon, Opal Nonsense
- Codons, Opal Nonsense
- Nonsense Codon, Opal
- Nonsense Codons, Opal
- Opal Nonsense Codons
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Below are MeSH descriptors whose meaning is more general than "Codon, Nonsense".
Below are MeSH descriptors whose meaning is more specific than "Codon, Nonsense".
This graph shows the total number of publications written about "Codon, Nonsense" by people in this website by year, and whether "Codon, Nonsense" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2001 | 1 | 1 | 2 | | 2002 | 0 | 2 | 2 | | 2003 | 0 | 3 | 3 | | 2005 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 2 | 2 | | 2012 | 0 | 1 | 1 | | 2014 | 1 | 3 | 4 | | 2015 | 0 | 2 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 2 | 1 | 3 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Codon, Nonsense" by people in Profiles.
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Wrenbeck EE, Bedewitz MA, Klesmith JR, Noshin S, Barry CS, Whitehead TA. An Automated Data-Driven Pipeline for Improving Heterologous Enzyme Expression. ACS Synth Biol. 2019 03 15; 8(3):474-481.
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Minto H, Mensah KA, Reynolds PR, Meffre E, Rubtsova K, Gelfand EW. A novel ATM mutation associated with elevated atypical lymphocyte populations, hyper-IgM, and cutaneous granulomas. Clin Immunol. 2019 03; 200:55-63.
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Schrauwen I, Giese AP, Aziz A, Lafont DT, Chakchouk I, Santos-Cortez RLP, Lee K, Acharya A, Khan FS, Ullah A, Nickerson DA, Bamshad MJ, Ali G, Riazuddin S, Ansar M, Ahmad W, Ahmed ZM, Leal SM. FAM92A Underlies Nonsyndromic Postaxial Polydactyly in Humans and an Abnormal Limb and Digit Skeletal Phenotype in Mice. J Bone Miner Res. 2019 02; 34(2):375-386.
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Knight S, VanHouwelingen L, Cervi D, Clay MR, Corkins M, Hines-Dowell S, Hamilton KV, Mostafavi R, Ward J, Furman WL, Murphy AJ. Genitopatellar syndrome and neuroblastoma: The multidisciplinary management of a previously unreported association. Pediatr Blood Cancer. 2018 12; 65(12):e27373.
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Li J, Zheng H, Wang W, Miao Y, Sheng Y, Feng C. Role of an isoform-specific residue at the calmodulin-heme (NO synthase) interface in the FMN - heme electron transfer. FEBS Lett. 2018 07; 592(14):2425-2431.
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Styrkarsdottir U, Helgason H, Sigurdsson A, Norddahl GL, Agustsdottir AB, Reynard LN, Villalvilla A, Halldorsson GH, Jonasdottir A, Magnusdottir A, Oddson A, Sulem G, Zink F, Sveinbjornsson G, Helgason A, Johannsdottir HS, Helgadottir A, Stefansson H, Gretarsdottir S, Rafnar T, Almdahl IS, Brækhus A, Fladby T, Selbæk G, Hosseinpanah F, Azizi F, Koh JM, Tang NLS, Daneshpour MS, Mayordomo JI, Welt C, Braund PS, Samani NJ, Kiemeney LA, Lohmander LS, Christiansen C, Andreassen OA, Magnusson O, Masson G, Kong A, Jonsdottir I, Gudbjartsson D, Sulem P, Jonsson H, Loughlin J, Ingvarsson T, Thorsteinsdottir U, Stefansson K. Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis. Nat Genet. 2017 May; 49(5):801-805.
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Jagannathan S, Bradley RK. Translational plasticity facilitates the accumulation of nonsense genetic variants in the human population. Genome Res. 2016 12; 26(12):1639-1650.
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Ullah R, Ansar M, Durrani ZU, Lee K, Santos-Cortez RL, Muhammad D, Ali M, Zia M, Ayub M, Khan S, Smith JD, Nickerson DA, Shendure J, Bamshad M, Leal SM, Ahmad W. Novel mutations in the genes TGM1 and ALOXE3 underlying autosomal recessive congenital ichthyosis. Int J Dermatol. 2016 May; 55(5):524-30.
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Lunetta KL, Day FR, Sulem P, Ruth KS, Tung JY, Hinds DA, Esko T, Elks CE, Altmaier E, He C, Huffman JE, Mihailov E, Porcu E, Robino A, Rose LM, Schick UM, Stolk L, Teumer A, Thompson DJ, Traglia M, Wang CA, Yerges-Armstrong LM, Antoniou AC, Barbieri C, Coviello AD, Cucca F, Demerath EW, Dunning AM, Gandin I, Grove ML, Gudbjartsson DF, Hocking LJ, Hofman A, Huang J, Jackson RD, Karasik D, Kriebel J, Lange EM, Lange LA, Langenberg C, Li X, Luan J, Mägi R, Morrison AC, Padmanabhan S, Pirie A, Polasek O, Porteous D, Reiner AP, Rivadeneira F, Rudan I, Sala CF, Schlessinger D, Scott RA, Stöckl D, Visser JA, Völker U, Vozzi D, Wilson JG, Zygmunt M, Boerwinkle E, Buring JE, Crisponi L, Easton DF, Hayward C, Hu FB, Liu S, Metspalu A, Pennell CE, Ridker PM, Strauch K, Streeten EA, Toniolo D, Uitterlinden AG, Ulivi S, Völzke H, Wareham NJ, Wellons M, Franceschini N, Chasman DI, Thorsteinsdottir U, Murray A, Stefansson K, Murabito JM, Ong KK, Perry JR. Rare coding variants and X-linked loci associated with age at menarche. Nat Commun. 2015 Aug 04; 6:7756.
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Kerem E, Konstan MW, De Boeck K, Accurso FJ, Sermet-Gaudelus I, Wilschanski M, Elborn JS, Melotti P, Bronsveld I, Fajac I, Malfroot A, Rosenbluth DB, Walker PA, McColley SA, Knoop C, Quattrucci S, Rietschel E, Zeitlin PL, Barth J, Elfring GL, Welch EM, Branstrom A, Spiegel RJ, Peltz SW, Ajayi T, Rowe SM. Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial. Lancet Respir Med. 2014 Jul; 2(7):539-47.
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