Tacrolimus Binding Protein 1A
"Tacrolimus Binding Protein 1A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 12-KDa tacrolimus binding protein that is found associated with and may modulate the function of calcium release channels. It is a peptidyl-prolyl cis/trans isomerase which is inhibited by both tacrolimus (commonly called FK506) and SIROLIMUS.
Descriptor ID |
D022061
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MeSH Number(s) |
D08.811.399.325.500.400.700.500 D12.776.543.750.705.400.700.500 D12.776.827.275.700.500
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Concept/Terms |
Tacrolimus Binding Protein 1A- Tacrolimus Binding Protein 1A
- Macrophilin-12
- Macrophilin 12
- FKBP-12
- FKBP 12
- FKBP12
- FK506-Binding Protein 1
- FK506 Binding Protein 1
- FK506-Binding Protein 1A
- FK506 Binding Protein 1A
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Below are MeSH descriptors whose meaning is more general than "Tacrolimus Binding Protein 1A".
Below are MeSH descriptors whose meaning is more specific than "Tacrolimus Binding Protein 1A".
This graph shows the total number of publications written about "Tacrolimus Binding Protein 1A" by people in this website by year, and whether "Tacrolimus Binding Protein 1A" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 | 2003 | 1 | 0 | 1 | 2004 | 0 | 1 | 1 | 2006 | 0 | 1 | 1 | 2007 | 1 | 0 | 1 | 2008 | 1 | 0 | 1 | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tacrolimus Binding Protein 1A" by people in Profiles.
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Battaglino RA, Jha P, Sultana F, Liu W, Morse LR. FKBP12: A partner of Snx10 required for vesicular trafficking in osteoclasts. J Cell Biochem. 2019 08; 120(8):13321-13329.
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Dabertrand F, Mironneau J, Henaff M, Macrez N, Morel JL. Comparison between gentamycin and exon skipping treatments to restore ryanodine receptor subtype 2 functions in mdx mouse duodenum myocytes. Eur J Pharmacol. 2010 Feb 25; 628(1-3):36-41.
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Hoeffer CA, Tang W, Wong H, Santillan A, Patterson RJ, Martinez LA, Tejada-Simon MV, Paylor R, Hamilton SL, Klann E. Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior. Neuron. 2008 Dec 10; 60(5):832-45.
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Shirts MR, Mobley DL, Chodera JD, Pande VS. Accurate and efficient corrections for missing dispersion interactions in molecular simulations. J Phys Chem B. 2007 Nov 15; 111(45):13052-63.
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Jayachandran G, Shirts MR, Park S, Pande VS. Parallelized-over-parts computation of absolute binding free energy with docking and molecular dynamics. J Chem Phys. 2006 Aug 28; 125(8):084901.
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Horswill AR, Savinov SN, Benkovic SJ. A systematic method for identifying small-molecule modulators of protein-protein interactions. Proc Natl Acad Sci U S A. 2004 Nov 02; 101(44):15591-6.
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Fong S, Mounkes L, Liu Y, Maibaum M, Alonzo E, Desprez PY, Thor AD, Kashani-Sabet M, Debs RJ. Functional identification of distinct sets of antitumor activities mediated by the FKBP gene family. Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24):14253-8.
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Soldevila G, Castellanos C, Malissen M, Berg LJ. Analysis of the individual role of the TCRzeta chain in transgenic mice after conditional activation with chemical inducers of dimerization. Cell Immunol. 2001 Dec 15; 214(2):123-38.
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