 Spectrometry, Mass, Secondary Ion
"Spectrometry, Mass, Secondary Ion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mass-spectrometric technique that is used for microscopic chemical analysis. A beam of primary ions with an energy of 5-20 kiloelectronvolts (keV) bombards a small spot on the surface of the sample under ultra-high vacuum conditions. Positive and negative secondary ions sputtered from the surface are analyzed in a mass spectrometer in regards to their mass-to-charge ratio. Digital imaging can be generated from the secondary ion beams and their intensity can be measured. Ionic images can be correlated with images from light or other microscopy providing useful tools in the study of molecular and drug actions.
| Descriptor ID |
D018629
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| MeSH Number(s) |
E05.196.566.760
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| Concept/Terms |
Spectrometry, Mass, Secondary Ion- Spectrometry, Mass, Secondary Ion
- Secondary Ion Mass Spectroscopy Microscopy
- Mass Spectrometry, Secondary Ion
- Secondary Ion Mass Spectrometry
- SIMS Microscopy
- Secondary Ion Mass Spectroscopy
- Mass Spectroscopy, Secondary Ion
- Spectroscopy, Mass, Secondary Ion
- Secondary Ion Mass Spectrometry Microscopy
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Below are MeSH descriptors whose meaning is more general than "Spectrometry, Mass, Secondary Ion".
Below are MeSH descriptors whose meaning is more specific than "Spectrometry, Mass, Secondary Ion".
This graph shows the total number of publications written about "Spectrometry, Mass, Secondary Ion" by people in this website by year, and whether "Spectrometry, Mass, Secondary Ion" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "Spectrometry, Mass, Secondary Ion" by people in Profiles.
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Spraker JE, Luu GT, Sanchez LM. Imaging mass spectrometry for natural products discovery: a review of ionization methods. Nat Prod Rep. 2020 02 26; 37(2):150-162.
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Sawyer RT, Abraham JL, Daniloff E, Newman LS. Secondary ion mass spectroscopy demonstrates retention of beryllium in chronic beryllium disease granulomas. J Occup Environ Med. 2005 Dec; 47(12):1218-26.
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Dixit BL, Balendiran GK, Watowich SJ, Srivastava S, Ramana KV, Petrash JM, Bhatnagar A, Srivastava SK. Kinetic and structural characterization of the glutathione-binding site of aldose reductase. J Biol Chem. 2000 Jul 14; 275(28):21587-95.
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Meyer K, Fobker M, Christians U, Erren M, Sewing KF, Assmann G, Benninghoven A. Characterization of glucuronidated phase II metabolites of the immunosuppressant cyclosporine in urine of transplant patients using time-of-flight secondary-ion mass spectrometry. Drug Metab Dispos. 1996 Oct; 24(10):1151-4.
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