 Leptin
"Leptin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.
| Descriptor ID |
D020738
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| MeSH Number(s) |
D06.472.699.042.500 D12.644.276.024.500 D12.644.548.011.500 D12.776.467.024.500 D23.529.024.500
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| Concept/Terms |
Leptin- Leptin
- Obese Protein
- Obese Gene Product
- Gene Product, Obese
- Ob Gene Product
- Gene Product, Ob
- Ob Protein
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Below are MeSH descriptors whose meaning is more general than "Leptin".
Below are MeSH descriptors whose meaning is more specific than "Leptin".
This graph shows the total number of publications written about "Leptin" by people in this website by year, and whether "Leptin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 0 | 8 | 8 | | 1998 | 0 | 4 | 4 | | 1999 | 1 | 3 | 4 | | 2000 | 4 | 0 | 4 | | 2001 | 1 | 1 | 2 | | 2002 | 2 | 1 | 3 | | 2003 | 6 | 2 | 8 | | 2004 | 2 | 4 | 6 | | 2005 | 2 | 6 | 8 | | 2006 | 2 | 5 | 7 | | 2007 | 5 | 4 | 9 | | 2008 | 3 | 4 | 7 | | 2009 | 2 | 3 | 5 | | 2010 | 5 | 8 | 13 | | 2011 | 3 | 1 | 4 | | 2012 | 2 | 2 | 4 | | 2013 | 2 | 5 | 7 | | 2014 | 3 | 8 | 11 | | 2015 | 3 | 5 | 8 | | 2016 | 4 | 2 | 6 | | 2017 | 3 | 1 | 4 | | 2018 | 1 | 5 | 6 | | 2019 | 0 | 6 | 6 | | 2020 | 4 | 3 | 7 | | 2021 | 1 | 1 | 2 | | 2022 | 2 | 7 | 9 |
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Below are the most recent publications written about "Leptin" by people in Profiles.
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Baker JF, England BR, George MD, Wysham K, Johnson T, Kunkel G, Sauer B, Hamilton BC, Hunter CD, Duryee MJ, Monach P, Kerr G, Reimold A, Xiao R, Thiele GM, Mikuls TR. Elevations in adipocytokines and mortality in rheumatoid arthritis. Rheumatology (Oxford). 2022 Nov 28; 61(12):4924-4934.
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Federico LE, Johnson TM, England BR, Wysham KD, George MD, Sauer B, Hamilton BC, Hunter CD, Duryee MJ, Thiele GM, Mikuls TR, Baker JF. Circulating Adipokines and Associations With Incident Cardiovascular Disease in Rheumatoid Arthritis. Arthritis Care Res (Hoboken). 2023 04; 75(4):768-777.
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McCullough D, Harrison T, Boddy LM, Enright KJ, Amirabdollahian F, Schmidt MA, Doenges K, Quinn K, Reisdorph N, Mazidi M, Lane KE, Stewart CE, Davies IG. The Effect of Dietary Carbohydrate and Fat Manipulation on the Metabolome and Markers of Glucose and Insulin Metabolism: A Randomised Parallel Trial. Nutrients. 2022 Sep 07; 14(18).
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Park A, Ryder S, Sevigny M, Monden KR, Battaglino RA, Nguyen N, Goldstein R, Morse LR. Association between weekly exercise minutes and resting IL-6 in adults with chronic spinal cord injury: findings from the fracture risk after spinal cord injury exercise study. Spinal Cord. 2022 10; 60(10):917-921.
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Gavin KM, Sullivan TM, Maltzahn JK, Jackman MR, Libby AE, MacLean PS, Kohrt WM, Majka SM, Klemm DJ. Hematopoietic Stem Cell-Derived Adipocytes Modulate Adipose Tissue Cellularity, Leptin Production and Insulin Responsiveness in Female Mice. Front Endocrinol (Lausanne). 2022; 13:844877.
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McDonald R, Kuhn K, Nguyen TB, Tannous A, Schauer I, Santoro N, Bradford AP. A randomized clinical trial demonstrating cell type specific effects of hyperlipidemia and hyperinsulinemia on pituitary function. PLoS One. 2022; 17(5):e0268323.
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Hoppe JE, Wagner BD, Kirk Harris J, Rowe SM, Heltshe SL, DeBoer EM, Sagel SD. Effects of ivacaftor on systemic inflammation and the plasma proteome in people with CF and G551D. J Cyst Fibros. 2022 Nov; 21(6):950-958.
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Baker JF, England BR, George MD, Wysham K, Johnson T, Lenert A, Kunkel G, Sauer B, Duryee MJ, Monach P, Kerr G, Reimold A, Thiele GM, Mikuls TR. Adipocytokines and achievement of low disease activity in rheumatoid arthritis. Semin Arthritis Rheum. 2022 08; 55:152003.
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?akir I, Hadley CK, Pan PL, Bagchi RA, Ghamari-Langroudi M, Porter DT, Wang Q, Litt MJ, Jana S, Hagen S, Lee P, White A, Lin JD, McKinsey TA, Cone RD. Histone deacetylase 6 inhibition restores leptin sensitivity and reduces obesity. Nat Metab. 2022 01; 4(1):44-59.
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Francis EC, Dabelea D, Shankar K, Perng W. Maternal diet quality during pregnancy is associated with biomarkers of metabolic risk among male offspring. Diabetologia. 2021 11; 64(11):2478-2490.
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