 Complement C1 Inhibitor Protein
"Complement C1 Inhibitor Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An endogenous 105-kDa plasma glycoprotein produced primarily by the LIVER and MONOCYTES. It inhibits a broad spectrum of proteases, including the COMPLEMENT C1R and the COMPLEMENT C1S proteases of the CLASSICAL COMPLEMENT PATHWAY, and the MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. C1-INH-deficient individuals suffer from HEREDITARY ANGIOEDEMA TYPES I AND II.
| Descriptor ID |
D050718
|
| MeSH Number(s) |
D12.644.861.140.500 D12.776.124.486.274.920.250.500 D12.776.395.320 D12.776.872.140.500
|
| Concept/Terms |
Complement C1 Inhibitor Protein- Complement C1 Inhibitor Protein
- Serpin Family G Member 1
- C1 Esterase Inhibitor
- Esterase Inhibitor, C1
- C1-Inhibitor Protein
- C1 Inhibitor Protein
- Serpin G1
- G1, Serpin
- Plasma Protease C1 Inhibitor
- Complement C1-Inhibitor Protein
- SERPING1
- C1-INH Protein
- C1 INH Protein
|
Below are MeSH descriptors whose meaning is more general than "Complement C1 Inhibitor Protein".
Below are MeSH descriptors whose meaning is more specific than "Complement C1 Inhibitor Protein".
This graph shows the total number of publications written about "Complement C1 Inhibitor Protein" by people in this website by year, and whether "Complement C1 Inhibitor Protein" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 | | 2012 | 1 | 1 | 2 | | 2014 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Complement C1 Inhibitor Protein" by people in Profiles.
-
Krack AT, Bernstein JA, Ruddy RM. Recognition, Evaluation, and Management of Pediatric Hereditary Angioedema. Pediatr Emerg Care. 2021 Apr 01; 37(4):218-223.
-
Chan ED, Majluf-Cruz A. Hereditary Angioedema. N Engl J Med. 2020 07 23; 383(4):e20.
-
Poppelaars F, Jager NM, Kotimaa J, Leuvenink HGD, Daha MR, van Kooten C, Seelen MA, Damman J. C1-Inhibitor Treatment Decreases Renal Injury in an Established Brain-Dead Rat Model. Transplantation. 2018 01; 102(1):79-87.
-
Smathers RL, Chiang DJ, McMullen MR, Feldstein AE, Roychowdhury S, Nagy LE. Soluble IgM links apoptosis to complement activation in early alcoholic liver disease in mice. Mol Immunol. 2016 Apr; 72:9-18.
-
Li HH, Busse P, Lumry WR, Frazer-Abel A, Levy H, Steele T, Dayno J, Riedl M. Comparison of chromogenic and ELISA functional C1 inhibitor tests in diagnosing hereditary angioedema. J Allergy Clin Immunol Pract. 2015 Mar-Apr; 3(2):200-5.
-
Riguzzi C, Losonczy L, Teismann N, Herring AA, Nagdev A. Gastrointestinal manifestations of hereditary angioedema diagnosed by ultrasound in the emergency department. West J Emerg Med. 2014 Nov; 15(7):816-8.
-
Zhang Q, Fillmore TL, Schepmoes AA, Clauss TR, Gritsenko MA, Mueller PW, Rewers M, Atkinson MA, Smith RD, Metz TO. Serum proteomics reveals systemic dysregulation of innate immunity in type 1 diabetes. J Exp Med. 2013 Jan 14; 210(1):191-203.
-
Zuraw BL, Bork K, Binkley KE, Banerji A, Christiansen SC, Castaldo A, Kaplan A, Riedl M, Kirkpatrick C, Magerl M, Drouet C, Cicardi M. Hereditary angioedema with normal C1 inhibitor function: consensus of an international expert panel. Allergy Asthma Proc. 2012 Nov-Dec; 33 Suppl 1:S145-56.
-
Lunn ML, Santos CB, Craig TJ. Is there a need for clinical guidelines in the United States for the diagnosis of hereditary angioedema and the screening of family members of affected patients? Ann Allergy Asthma Immunol. 2010 Mar; 104(3):211-4.
-
Baig K, Nassar R, Craig DM, Quick G, Jiang HX, Frank MM, Lodge AJ, Anderson PA, Jaggers J. Complement factor 1 inhibitor improves cardiopulmonary function in neonatal cardiopulmonary bypass. Ann Thorac Surg. 2007 Apr; 83(4):1477-82; discussion 1483.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|