 Extracellular Signal-Regulated MAP Kinases
"Extracellular Signal-Regulated MAP Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation of MEIOSIS; MITOSIS; and post mitotic functions in differentiated cells. The extracellular signal regulated MAP kinases are regulated by a broad variety of CELL SURFACE RECEPTORS and can be activated by certain CARCINOGENS.
| Descriptor ID |
D048049
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| MeSH Number(s) |
D08.811.913.696.620.682.700.567.249 D12.644.360.450.169 D12.776.476.450.169
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| Concept/Terms |
Extracellular Signal-Regulated MAP Kinases- Extracellular Signal-Regulated MAP Kinases
- Extracellular Signal Regulated MAP Kinases
- MAP Kinases, Extracellular Signal-Regulated
- MAP Kinases, Extracellular Signal Regulated
- ERK MAP Kinases
- Extracellular Signal-Regulated Kinases
- Extracellular Signal Regulated Kinases
- Kinases, Extracellular Signal-Regulated
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Below are MeSH descriptors whose meaning is more general than "Extracellular Signal-Regulated MAP Kinases".
Below are MeSH descriptors whose meaning is more specific than "Extracellular Signal-Regulated MAP Kinases".
This graph shows the total number of publications written about "Extracellular Signal-Regulated MAP Kinases" by people in this website by year, and whether "Extracellular Signal-Regulated MAP Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2004 | 1 | 1 | 2 | | 2005 | 3 | 3 | 6 | | 2006 | 3 | 9 | 12 | | 2007 | 1 | 6 | 7 | | 2008 | 2 | 5 | 7 | | 2009 | 2 | 9 | 11 | | 2010 | 3 | 4 | 7 | | 2011 | 4 | 3 | 7 | | 2012 | 1 | 5 | 6 | | 2013 | 2 | 6 | 8 | | 2014 | 1 | 7 | 8 | | 2015 | 1 | 6 | 7 | | 2016 | 1 | 4 | 5 | | 2017 | 1 | 2 | 3 | | 2018 | 0 | 1 | 1 | | 2019 | 2 | 2 | 4 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Extracellular Signal-Regulated MAP Kinases" by people in Profiles.
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Pozdeyev N, Rose MM, Bowles DW, Schweppe RE. Molecular therapeutics for anaplastic thyroid cancer. Semin Cancer Biol. 2020 04; 61:23-29.
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Castillo-Castrejon M, Jansson T, Powell TL. No evidence of attenuation of placental insulin-stimulated Akt phosphorylation and amino acid transport in maternal obesity and gestational diabetes mellitus. Am J Physiol Endocrinol Metab. 2019 12 01; 317(6):E1037-E1049.
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Pegram LM, Liddle JC, Xiao Y, Hoh M, Rudolph J, Iverson DB, Vigers GP, Smith D, Zhang H, Wang W, Moffat JG, Ahn NG. Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2. Proc Natl Acad Sci U S A. 2019 07 30; 116(31):15463-15468.
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Aziz AH, Eckstein K, Ferguson VL, Bryant SJ. The effects of dynamic compressive loading on human mesenchymal stem cell osteogenesis in the stiff layer of a bilayer hydrogel. J Tissue Eng Regen Med. 2019 06; 13(6):946-959.
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Ohm AM, Affandi T, Reyland ME. EGF receptor and PKCd kinase activate DNA damage-induced pro-survival and pro-apoptotic signaling via biphasic activation of ERK and MSK1 kinases. J Biol Chem. 2019 03 22; 294(12):4488-4497.
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Greaves SA, Peterson JN, Torres RM, Pelanda R. Activation of the MEK-ERK Pathway Is Necessary but Not Sufficient for Breaking Central B Cell Tolerance. Front Immunol. 2018; 9:707.
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Hammerlindl H, Ravindran Menon D, Hammerlindl S, Emran AA, Torrano J, Sproesser K, Thakkar D, Xiao M, Atkinson VG, Gabrielli B, Haass NK, Herlyn M, Krepler C, Schaider H. Acetylsalicylic Acid Governs the Effect of Sorafenib in RAS-Mutant Cancers. Clin Cancer Res. 2018 03 01; 24(5):1090-1102.
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Habibian JS, Jefic M, Bagchi RA, Lane RH, McKnight RA, McKinsey TA, Morrison RF, Ferguson BS. DUSP5 functions as a feedback regulator of TNFa-induced ERK1/2 dephosphorylation and inflammatory gene expression in adipocytes. Sci Rep. 2017 10 10; 7(1):12879.
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Chang KC, Shieh B, Petrash JM. Influence of aldose reductase on epithelial-to-mesenchymal transition signaling in lens epithelial cells. Chem Biol Interact. 2017 Oct 01; 276:149-154.
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Chen D, Ireland SJ, Remington G, Alvarez E, Racke MK, Greenberg B, Frohman EM, Monson NL. CD40-Mediated NF-?B Activation in B Cells Is Increased in Multiple Sclerosis and Modulated by Therapeutics. J Immunol. 2016 12 01; 197(11):4257-4265.
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