 Calcium Signaling
"Calcium Signaling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.
| Descriptor ID |
D020013
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| MeSH Number(s) |
G02.111.820.800.100 G03.143.500.100 G04.835.800.100
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| Concept/Terms |
Calcium Signaling- Calcium Signaling
- Calcium Signalings
- Signaling, Calcium
- Signalings, Calcium
Calcium Waves- Calcium Waves
- Calcium Wave
- Wave, Calcium
- Waves, Calcium
- Calcium Oscillations
- Calcium Oscillation
- Oscillation, Calcium
- Oscillations, Calcium
Calcium Spikes- Calcium Spikes
- Calcium Spike
- Spike, Calcium
- Spikes, Calcium
Calcium Puffs- Calcium Puffs
- Calcium Puff
- Puff, Calcium
- Puffs, Calcium
Calcium Sparks- Calcium Sparks
- Calcium Spark
- Spark, Calcium
- Sparks, Calcium
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Below are MeSH descriptors whose meaning is more general than "Calcium Signaling".
Below are MeSH descriptors whose meaning is more specific than "Calcium Signaling".
This graph shows the total number of publications written about "Calcium Signaling" by people in this website by year, and whether "Calcium Signaling" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 2 | 2 | 4 | | 2001 | 5 | 2 | 7 | | 2002 | 5 | 4 | 9 | | 2003 | 0 | 5 | 5 | | 2004 | 3 | 2 | 5 | | 2005 | 2 | 5 | 7 | | 2006 | 3 | 6 | 9 | | 2007 | 5 | 3 | 8 | | 2008 | 9 | 6 | 15 | | 2009 | 5 | 6 | 11 | | 2010 | 5 | 3 | 8 | | 2011 | 4 | 2 | 6 | | 2012 | 3 | 7 | 10 | | 2013 | 2 | 8 | 10 | | 2014 | 5 | 2 | 7 | | 2015 | 4 | 5 | 9 | | 2016 | 5 | 3 | 8 | | 2017 | 4 | 6 | 10 | | 2018 | 2 | 5 | 7 | | 2019 | 2 | 6 | 8 | | 2020 | 7 | 0 | 7 | | 2021 | 3 | 2 | 5 | | 2022 | 0 | 1 | 1 | | 2023 | 1 | 1 | 2 | | 2024 | 0 | 5 | 5 | | 2025 | 2 | 1 | 3 |
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Below are the most recent publications written about "Calcium Signaling" by people in Profiles.
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Mull ML, Pratt SJP, Thompson KN, Annis DA, Lee RM, Ju JA, Gilchrist DE, Stemberger MB, Boyman L, Lederer WJ, Vitolo MI, Martin SS. Disruption of P2Y2 Signaling Promotes Breast Tumor Cell Dissemination by Reducing ATP-Dependent Calcium Elevation and Actin Localization to Cell Junctions. Int J Mol Sci. 2025 May 01; 26(9).
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Jin E, Briggs JK, Benninger RKP, Merrins MJ. Glucokinase activity controls peripherally located subpopulations of ?-cells that lead islet Ca2+ oscillations. Elife. 2025 Feb 12; 13.
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Zent KH, Dell'Acqua ML. Synapse-to-Nucleus ERK?CREB Transcriptional Signaling Requires Dendrite-to-Soma Ca2+ Propagation Mediated by L-Type Voltage-Gated Ca2+ Channels. J Neurosci. 2025 Jan 22; 45(4).
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Simoes de Souza FM, Williamson R, McCullough C, Teel A, Futia G, Ma M, True A, Crimaldi JP, Gibson E, Restrepo D. Miniscope Recording Calcium Signals at Hippocampus of Mice Navigating an Odor Plume. J Vis Exp. 2024 Sep 20; (211).
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Dittmer PJ, Dell'Acqua ML. L-type Ca2+ channel activation of STIM1-Orai1 signaling remodels the dendritic spine ER to maintain long-term structural plasticity. Proc Natl Acad Sci U S A. 2024 Aug 27; 121(35):e2407324121.
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Rutter GA, Gresch A, Delgadillo Silva L, Benninger RKP. Exploring pancreatic beta-cell subgroups and their connectivity. Nat Metab. 2024 Nov; 6(11):2039-2053.
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?terk M, Zhang Y, Pohorec V, Leitgeb EP, Dolen?ek J, Benninger RKP, Sto?er A, Kravets V, Gosak M. Network representation of multicellular activity in pancreatic islets: Technical considerations for functional connectivity analysis. PLoS Comput Biol. 2024 May; 20(5):e1012130.
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Guevara A, Smith CER, Caldwell JL, Ngo L, Mott LR, Lee IJ, Tapa S, Wang Z, Wang L, Woodward WR, Ng GA, Habecker BA, Ripplinger CM. Chronic nicotine exposure is associated with electrophysiological and sympathetic remodeling in the intact rabbit heart. Am J Physiol Heart Circ Physiol. 2024 06 01; 326(6):H1337-H1349.
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Schaid TR, Mitra S, Stafford P, DeBot M, Thielen O, Hallas W, Cralley A, Gallagher L, Jeffrey D, Hansen KC, D'Alessandro A, Silliman CC, Dabertrand F, Cohen MJ. Endothelial Cell Calcium Influx Mediates Trauma-induced Endothelial Permeability. Ann Surg. 2025 Apr 01; 281(4):671-681.
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Figueroa NE, Franz P, Luzarowski M, Martinez-Seidel F, Moreno JC, Childs D, Ziemblicka A, Sampathkumar A, Andersen TG, Tsiavaliaris G, Chodasiewicz M, Skirycz A. Protein interactome of 3',5'-cAMP reveals its role in regulating the actin cytoskeleton. Plant J. 2023 09; 115(5):1214-1230.
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