 Protein Aggregates
"Protein Aggregates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any mixture of secondary, tertiary, or quaternary protein molecules which appear as clumps in or outside the cell.
| Descriptor ID |
D066329
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| MeSH Number(s) |
D05.875
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Protein Aggregates".
Below are MeSH descriptors whose meaning is more specific than "Protein Aggregates".
This graph shows the total number of publications written about "Protein Aggregates" by people in this website by year, and whether "Protein Aggregates" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 2 | 3 | | 2013 | 0 | 1 | 1 | | 2014 | 5 | 3 | 8 | | 2015 | 2 | 3 | 5 | | 2016 | 6 | 4 | 10 | | 2017 | 3 | 3 | 6 | | 2018 | 7 | 6 | 13 | | 2019 | 2 | 5 | 7 | | 2020 | 4 | 3 | 7 | | 2021 | 2 | 2 | 4 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Aggregates" by people in Profiles.
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Thackray AM, Lam B, McNulty EE, Nalls AV, Mathiason CK, Magadi SS, Jackson WS, Andréoletti O, Marrero-Winkens C, Schätzl H, Bujdoso R. Clearance of variant Creutzfeldt-Jakob disease prions in vivo by the Hsp70 disaggregase system. Brain. 2022 Sep 14; 145(9):3236-3249.
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Calderon CP, Ripple DC, Srinivasan C, Ma Y, Carrier MJ, Randolph TW, O'Connor TF. Testing Precision Limits of Neural Network-Based Quality Control Metrics in High-Throughput Digital Microscopy. Pharm Res. 2022 Feb; 39(2):263-279.
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Bantle CM, Rocha SM, French CT, Phillips AT, Tran K, Olson KE, Bass TA, Aboellail T, Smeyne RJ, Tjalkens RB. Astrocyte inflammatory signaling mediates a-synuclein aggregation and dopaminergic neuronal loss following viral encephalitis. Exp Neurol. 2021 12; 346:113845.
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Corbet GA, Wheeler JR, Parker R, Weskamp K. TDP43 ribonucleoprotein granules: physiologic function to pathologic aggregates. RNA Biol. 2021 10 15; 18(sup1):128-138.
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Movafaghi S, Daniels AL, Kelly MD, Witeof AE, Calderon CP, Randolph TW, Goodwin AP. Hydrogel Coatings on Container Surfaces Reduce Protein Aggregation Caused by Mechanical Stress and Cavitation. ACS Appl Bio Mater. 2021 09 20; 4(9):6946-6953.
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Anderson EN, Morera AA, Kour S, Cherry JD, Ramesh N, Gleixner A, Schwartz JC, Ebmeier C, Old W, Donnelly CJ, Cheng JP, Kline AE, Kofler J, Stein TD, Pandey UB. Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology. Elife. 2021 05 26; 10.
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Witeof AE, Daniels AL, Rea LT, Movafaghi S, Kurtz K, Davis M, Eveland RW, Calderon CP, Randolph TW. Machine Learning and Accelerated Stress Approaches to Differentiate Potential Causes of Aggregation in Polyclonal Antibody Formulations During Shipping. J Pharm Sci. 2021 07; 110(7):2743-2752.
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Nuckolls NL, Mok AC, Lange JJ, Yi K, Kandola TS, Hunn AM, McCroskey S, Snyder JL, Bravo Núñez MA, McClain M, McKinney SA, Wood C, Halfmann R, Zanders SE. The wtf4 meiotic driver utilizes controlled protein aggregation to generate selective cell death. Elife. 2020 10 27; 9.
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Chaparro Sosa AF, de Oliveira da Silva SM, Morgan GP, Schwartz DK, Kaar JL. Mixed Phospholipid Vesicles Catalytically Inhibit and Reverse Amyloid Fibril Formation. J Phys Chem Lett. 2020 Sep 03; 11(17):7417-7422.
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Vanbillemont B, Carpenter JF, Probst C, De Beer T. The Impact of Formulation Composition and Process Settings of Traditional Batch Versus Continuous Freeze-Drying On Protein Aggregation. J Pharm Sci. 2020 11; 109(11):3308-3318.
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