Phosphatidylinositol 3-Kinase
"Phosphatidylinositol 3-Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphatidylinositol 3-kinase that catalyzes the conversion of 1-phosphatidylinositol into 1-phosphatidylinositol 3-phosphate.
Descriptor ID |
D058539
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MeSH Number(s) |
D08.811.913.696.620.500.100
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Concept/Terms |
Phosphatidylinositol 3-Kinase- Phosphatidylinositol 3-Kinase
- Phosphatidylinositol 3 Kinase
- 1-Phosphatidylinositol 3-Kinase
- 1 Phosphatidylinositol 3 Kinase
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Below are MeSH descriptors whose meaning is more general than "Phosphatidylinositol 3-Kinase".
Below are MeSH descriptors whose meaning is more specific than "Phosphatidylinositol 3-Kinase".
This graph shows the total number of publications written about "Phosphatidylinositol 3-Kinase" by people in this website by year, and whether "Phosphatidylinositol 3-Kinase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 0 | 1 | 1 | 2011 | 0 | 1 | 1 | 2012 | 0 | 2 | 2 | 2013 | 0 | 1 | 1 | 2014 | 0 | 2 | 2 | 2015 | 0 | 1 | 1 | 2016 | 2 | 0 | 2 | 2018 | 1 | 0 | 1 | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosphatidylinositol 3-Kinase" by people in Profiles.
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Franks SE, Getahun A, Cambier JC. A Precision B Cell-Targeted Therapeutic Approach to Autoimmunity Caused by Phosphatidylinositol 3-Kinase Pathway Dysregulation. J Immunol. 2019 06 15; 202(12):3381-3393.
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Roof AK, Jirawatnotai S, Trudeau T, Kuzyk C, Wierman ME, Kiyokawa H, Gutierrez-Hartmann A. The Balance of PI3K and ERK Signaling Is Dysregulated in Prolactinoma and Modulated by Dopamine. Endocrinology. 2018 06 01; 159(6):2421-2434.
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Ziemba BP, Swisher GH, Masson G, Burke JE, Williams RL, Falke JJ. Regulation of a Coupled MARCKS-PI3K Lipid Kinase Circuit by Calmodulin: Single-Molecule Analysis of a Membrane-Bound Signaling Module. Biochemistry. 2016 Nov 22; 55(46):6395-6405.
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Keysar SB, Le PN, Miller B, Jackson BC, Eagles JR, Nieto C, Kim J, Tang B, Glogowska MJ, Morton JJ, Padilla-Just N, Gomez K, Warnock E, Reisinger J, Arcaroli JJ, Messersmith WA, Wakefield LM, Gao D, Tan AC, Serracino H, Vasiliou V, Roop DR, Wang XJ, Jimeno A. Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2. J Natl Cancer Inst. 2017 01; 109(1).
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Lyu H, Huang J, Edgerton SM, Thor AD, He Z, Liu B. Increased erbB3 promotes erbB2/neu-driven mammary tumor proliferation and co-targeting of erbB2/erbB3 receptors exhibits potent inhibitory effects on breast cancer cells. Int J Clin Exp Pathol. 2015; 8(6):6143-56.
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Song Z, Levin BE, Stevens W, Sladek CD. Supraoptic oxytocin and vasopressin neurons function as glucose and metabolic sensors. . 2014 Apr 01; 306(7):R447-56.
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Derry MM, Somasagara RR, Raina K, Kumar S, Gomez J, Patel M, Agarwal R, Agarwal C. Target identification of grape seed extract in colorectal cancer using drug affinity responsive target stability (DARTS) technique: role of endoplasmic reticulum stress response proteins. Curr Cancer Drug Targets. 2014; 14(4):323-36.
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Garat CV, Crossno JT, Sullivan TM, Reusch JE, Klemm DJ. Inhibition of phosphatidylinositol 3-kinase/Akt signaling attenuates hypoxia-induced pulmonary artery remodeling and suppresses CREB depletion in arterial smooth muscle cells. J Cardiovasc Pharmacol. 2013 Dec; 62(6):539-48.
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Peng F, Yao H, Akturk HK, Buch S. Platelet-derived growth factor CC-mediated neuroprotection against HIV Tat involves TRPC-mediated inactivation of GSK 3beta. PLoS One. 2012; 7(10):e47572.
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Rückerl D, Jenkins SJ, Laqtom NN, Gallagher IJ, Sutherland TE, Duncan S, Buck AH, Allen JE. Induction of IL-4Ra-dependent microRNAs identifies PI3K/Akt signaling as essential for IL-4-driven murine macrophage proliferation in vivo. Blood. 2012 Sep 13; 120(11):2307-16.
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