Proof of Concept Study
"Proof of Concept Study" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An empirical investigation which pertains to the development of prototypes or models that demonstrate the feasibility of novel concepts, ideas, principles, schema or their practical application.
Descriptor ID 
D000075082

MeSH Number(s) 
H01.770.644.578

Concept/Terms 
Proof of Concept Study Proof of Concept Study
 Concept Study Proof
 Study Proof, Concept
 Proof of Concept Investigation
 Concept Investigation Proof
 Investigation Proof, Concept
 Proof of Concept Research
 Concept Research Proof
 Concept Research Proofs
 Research Proof, Concept
 Proof of Concept Testing
 Concept Testing Proof
 Concept Testing Proofs
 Testing Proof, Concept
 Testing Proofs, Concept
 Proof of Concept Experiment
 Concept Experiment Proof
 Concept Experiment Proofs
 Experiment Proof, Concept
 Proof of Concept Approach
 Approach Proof, Concept
 Approach Proofs, Concept
 Concept Approach Proof
 Concept Approach Proofs
 Proof of Concept Studies
Proof of Concept Prototype Proof of Concept Prototype
 Concept Prototype Proof
 Concept Prototype Proofs
 Prototype Proof, Concept
 Proof of Concept Model
 Concept Model Proof
 Concept Model Proofs
 Model Proof, Concept
Proof of Concept Evaluation Proof of Concept Evaluation
 Concept Evaluation Proof
 Concept Evaluation Proofs
 Evaluation Proof, Concept
 Proof of Concept Demonstration
 Concept Demonstration Proof
 Demonstration Proof, Concept

Below are MeSH descriptors whose meaning is more general than "Proof of Concept Study".
Below are MeSH descriptors whose meaning is more specific than "Proof of Concept Study".
This graph shows the total number of publications written about "Proof of Concept Study" by people in this website by year, and whether "Proof of Concept Study" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year  Major Topic  Minor Topic  Total 

2015  0  1  1  2016  0  3  3  2018  0  5  5  2019  0  6  6  2020  0  6  6 
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Below are the most recent publications written about "Proof of Concept Study" by people in Profiles.

Frederick BA, Gupta R, AtilanoRoque A, Su TT, Raben D. Combined EGFR1 and PARP1 Inhibition Enhances the Effect of Radiation in Head and Neck Squamous Cell Carcinoma Models. Radiat Res. 2020 11 10; 194(5):519531.

Kheyfets VO, Lammers SR, Wagner J, Bartels K, Piccoli J, Smith BJ. PEEP/ FIO2 ARDSNet Scale Grouping of a Single Ventilator for Two Patients: Modeling Tidal Volume Response. Respir Care. 2020 08; 65(8):10941103.

Kornblith LZ, Bainton CMV, Fields AT, Matthay ZA, Magid NT, NunezGarcia B, Prakash A, Kurien PA, Callcut RA, Cohen MJ, Bainton RJ. A journey upstream: Fluctuating plateletspecific genes in cellfree plasma as proofofconcept for using ribonucleic acid sequencing to improve understanding of postinjury platelet biology. J Trauma Acute Care Surg. 2020 06; 88(6):742751.

Ehrmann DE, Leopold DK, Phillips R, Shahi N, Campbell K, Ross M, Zablah JE, Moulton SL, Morgan G, Kim JS. The Compensatory Reserve Index Responds to Acute Hemodynamic Changes in Patients with Congenital Heart Disease: A Proof of Concept Study. Pediatr Cardiol. 2020 Aug; 41(6):11901198.

LaRocca TJ, Seeger T, Prado M, PereaGil I, Neofytou E, Mecham BH, Ameen M, Chang ACY, Pandey G, Wu JC, Karakikes I. Pharmacological Silencing of MicroRNA152 Prevents Pressure OverloadInduced Heart Failure. Circ Heart Fail. 2020 03; 13(3):e006298.

Pu F, Pandey S, Bushman LR, Anderson PL, Ouyang Z, Cooks RG. Direct quantitation of tenofovir diphosphate in human blood with mass spectrometry for adherence monitoring. Anal Bioanal Chem. 2020 Feb; 412(6):12431249.

Voss MW, Weng TB, NarayanaKumanan K, Cole RC, Wharff C, Reist L, Dubose L, Sigurdsson G, Mills JA, Long JD, Magnotta VA, Pierce GL. Acute Exercise Effects Predict Training Change in Cognition and Connectivity. Med Sci Sports Exerc. 2020 01; 52(1):131140.

Holguin F, Grasemann H, Sharma S, Winnica D, Wasil K, Smith V, Cruse MH, Perez N, Coleman E, Scialla TJ, Que LG. LCitrulline increases nitric oxide and improves control in obese asthmatics. JCI Insight. 2019 12 19; 4(24).

Chen J, Cho M, Silverman EK, Hokanson JE, Kinney GL, Crapo JD, Rennard S, Dy J, Castaldi P. Turning subtypes into disease axes to improve prediction of COPD progression. Thorax. 2019 09; 74(9):906909.

Kline PW, Murray AM, Miller MJ, Fields T, Christiansen CL. Erroraugmentation gait training to improve gait symmetry in patients with nontraumatic lower limb amputation: A proofofconcept study. Prosthet Orthot Int. 2019 Aug; 43(4):426433.

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