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Copper-transporting ATPases

"Copper-transporting ATPases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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P-type ATPases which transport copper ions across membranes in prokaryotic and eukaryotic cells. They possess a conserved CYSTEINE-HISTIDINE-SERINE (CPx) amino acid motif within their transmembrane helices that functions in cation translocation and catalytic activation, and an N-terminal copper-binding CxxC motif that regulates enzyme activity. They play essential roles in intracellular copper homeostasis through regulating the uptake, efflux and storage of copper ions, and in cuproprotein biosynthesis.


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This graph shows the total number of publications written about "Copper-transporting ATPases" by people in this website by year, and whether "Copper-transporting ATPases" was a major or minor topic of these publications.
Bar chart showing 5 publications over 4 distinct years, with a maximum of 2 publications in 2009
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