 Homeobox Protein Nkx-2.5
"Homeobox Protein Nkx-2.5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A homeobox-containing transcription factor that functions in heart development. Mutations in the NKX2-5 gene are associated with ATRIAL SEPTAL DEFECTS and TETRALOGY OF FALLOT.
| Descriptor ID |
D000072576
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| MeSH Number(s) |
D12.776.260.400.234 D12.776.930.324
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| Concept/Terms |
Homeobox Protein Nkx-2.5- Homeobox Protein Nkx-2.5
- Homeobox Protein Nkx 2.5
- Nkx-2.5, Homeobox Protein
- NK2 Homeobox 5 Protein
- Homeobox Transcription Factor Csx-Nkx2-5
- Homeobox Transcription Factor Csx Nkx2 5
- Homeobox Protein Csx-Nkx2.5
- Csx-Nkx2.5, Homeobox Protein
- Homeobox Protein Csx Nkx2.5
- Cardiac-Specific Homeobox Protein
- Cardiac Specific Homeobox Protein
- Homeobox Protein, Cardiac-Specific
- Transcription Factor Nkx-2.5
- Nkx-2.5, Transcription Factor
- Transcription Factor Nkx 2.5
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Below are MeSH descriptors whose meaning is more general than "Homeobox Protein Nkx-2.5".
Below are MeSH descriptors whose meaning is more specific than "Homeobox Protein Nkx-2.5".
This graph shows the total number of publications written about "Homeobox Protein Nkx-2.5" by people in this website by year, and whether "Homeobox Protein Nkx-2.5" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Homeobox Protein Nkx-2.5" by people in Profiles.
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Ikl? JM, Tavares AL, King M, Ding H, Colombo S, Firulli BA, Firulli AB, Targoff KL, Yelon D, Clouthier DE. Nkx2.5 regulates endothelin converting enzyme-1 during pharyngeal arch patterning. Genesis. 2017 03; 55(3).
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Ashraf H, Pradhan L, Chang EI, Terada R, Ryan NJ, Briggs LE, Chowdhury R, Z?rate MA, Sugi Y, Nam HJ, Benson DW, Anderson RH, Kasahara H. A mouse model of human congenital heart disease: high incidence of diverse cardiac anomalies and ventricular noncompaction produced by heterozygous Nkx2-5 homeodomain missense mutation. Circ Cardiovasc Genet. 2014 Aug; 7(4):423-433.
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Zhou Y, Cashman TJ, Nevis KR, Obregon P, Carney SA, Liu Y, Gu A, Mosimann C, Sondalle S, Peterson RE, Heideman W, Burns CE, Burns CG. Latent TGF-? binding protein 3 identifies a second heart field in zebrafish. Nature. 2011 May 29; 474(7353):645-8.
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Ouyang P, Saarel E, Bai Y, Luo C, Lv Q, Xu Y, Wang F, Fan C, Younoszai A, Chen Q, Tu X, Wang QK. A de novo mutation in NKX2.5 associated with atrial septal defects, ventricular noncompaction, syncope and sudden death. Clin Chim Acta. 2011 Jan 14; 412(1-2):170-5.
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Song K, Backs J, McAnally J, Qi X, Gerard RD, Richardson JA, Hill JA, Bassel-Duby R, Olson EN. The transcriptional coactivator CAMTA2 stimulates cardiac growth by opposing class II histone deacetylases. Cell. 2006 May 05; 125(3):453-66.
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