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Protein Phosphatase 2C

"Protein Phosphatase 2C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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One of four major classes of mammalian serine/threonine specific protein phosphatases. Protein phosphatase 2C is a monomeric enzyme about 42 kDa in size. It shows broad substrate specificity dependent on divalent cations (mainly manganese and magnesium). Three isozymes are known in mammals: PP2C -alpha, -beta and -gamma. In yeast, there are four PP2C homologues: phosphatase PTC1 that have weak tyrosine phosphatase activity, phosphatase PTC2, phosphatase PTC3, and PTC4. Isozymes of PP2C also occur in Arabidopsis thaliana where the kinase-associated protein phosphatase (KAPP) containing a C-terminal PP2C domain, dephosphorylates Ser/Thr receptor-like kinase RLK5.


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This graph shows the total number of publications written about "Protein Phosphatase 2C" by people in this website by year, and whether "Protein Phosphatase 2C" was a major or minor topic of these publications.
Bar chart showing 6 publications over 6 distinct years, with a maximum of 1 publications in 2002 and 2006 and 2012 and 2015 and 2017 and 2020
To see the data from this visualization as text, click here.

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