V-Set Domain-Containing T-Cell Activation Inhibitor 1
"V-Set Domain-Containing T-Cell Activation Inhibitor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A B7 antigen subtype that inhibits the costimulation of T-cell activation, proliferation, cytokine production and development of cytotoxicity. The over expression of this protein in a variety of tumor cell types suggests its role in TUMOR IMMUNE EVASION.
Descriptor ID |
D060907
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MeSH Number(s) |
D12.776.467.150.900 D12.776.543.095.900 D23.050.301.285.900 D23.529.168.900
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Concept/Terms |
V-Set Domain-Containing T-Cell Activation Inhibitor 1- V-Set Domain-Containing T-Cell Activation Inhibitor 1
- V Set Domain Containing T Cell Activation Inhibitor 1
- Immune Costimulatory Protein B7-H4
- Immune Costimulatory Protein B7 H4
- T-Cell Costimulatory Molecule B7x
- T Cell Costimulatory Molecule B7x
- B7H4 Immune Costimulatory Protein
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Below are MeSH descriptors whose meaning is more general than "V-Set Domain-Containing T-Cell Activation Inhibitor 1".
Below are MeSH descriptors whose meaning is more specific than "V-Set Domain-Containing T-Cell Activation Inhibitor 1".
This graph shows the total number of publications written about "V-Set Domain-Containing T-Cell Activation Inhibitor 1" by people in this website by year, and whether "V-Set Domain-Containing T-Cell Activation Inhibitor 1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2005 | 0 | 2 | 2 | 2007 | 0 | 2 | 2 | 2008 | 0 | 1 | 1 | 2010 | 0 | 1 | 1 | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "V-Set Domain-Containing T-Cell Activation Inhibitor 1" by people in Profiles.
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Saha A, Taylor PA, Lees CJ, Panoskaltsis-Mortari A, Osborn MJ, Feser CJ, Thangavelu G, Melchinger W, Refaeli Y, Hill GR, Munn DH, Murphy WJ, Serody JS, Maillard I, Kreymborg K, van den Brink M, Dong C, Huang S, Zang X, Allison JP, Zeiser R, Blazar BR. Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality. JCI Insight. 2019 10 03; 4(19).
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Yee EU, Zaino RJ, Torkko KC, Shroyer KR. B7-H4 expression in Brenner tumours, a descriptive and comparative study. Histopathology. 2010 Apr; 56(5):652-4.
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Awadallah NS, Shroyer KR, Langer DA, Torkko KC, Chen YK, Bentz JS, Papkoff J, Liu W, Nash SR, Shah RJ. Detection of B7-H4 and p53 in pancreatic cancer: potential role as a cytological diagnostic adjunct. Pancreas. 2008 Mar; 36(2):200-6.
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Mugler KC, Singh M, Tringler B, Torkko KC, Liu W, Papkoff J, Shroyer KR. B7-h4 expression in a range of breast pathology: correlation with tumor T-cell infiltration. Appl Immunohistochem Mol Morphol. 2007 Dec; 15(4):363-70.
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Miyatake T, Tringler B, Liu W, Liu SH, Papkoff J, Enomoto T, Torkko KC, Dehn DL, Swisher A, Shroyer KR. B7-H4 (DD-O110) is overexpressed in high risk uterine endometrioid adenocarcinomas and inversely correlated with tumor T-cell infiltration. Gynecol Oncol. 2007 Jul; 106(1):119-27.
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Tringler B, Liu W, Corral L, Torkko KC, Enomoto T, Davidson S, Lucia MS, Heinz DE, Papkoff J, Shroyer KR. B7-H4 overexpression in ovarian tumors. Gynecol Oncol. 2006 Jan; 100(1):44-52.
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Tringler B, Zhuo S, Pilkington G, Torkko KC, Singh M, Lucia MS, Heinz DE, Papkoff J, Shroyer KR. B7-h4 is highly expressed in ductal and lobular breast cancer. Clin Cancer Res. 2005 Mar 01; 11(5):1842-8.
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