 Riboswitch
"Riboswitch" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Part of a MESSENGER RNA molecule that undergoes a conformation change upon binding a specific metabolite or other small molecule thereby regulating the messenger RNA's transcription, post-transcriptional processing, transport, translation, or stability in response to varying levels of the metabolite or other small molecule.
| Descriptor ID |
D058928
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| MeSH Number(s) |
D13.444.735.544.427 D13.444.735.790.878.942.500 G02.111.570.080.689.687.124 G05.360.080.689.687.124
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Riboswitch".
Below are MeSH descriptors whose meaning is more specific than "Riboswitch".
This graph shows the total number of publications written about "Riboswitch" by people in this website by year, and whether "Riboswitch" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 5 | 0 | 5 | | 2012 | 4 | 1 | 5 | | 2013 | 3 | 0 | 3 | | 2014 | 5 | 0 | 5 | | 2015 | 5 | 1 | 6 | | 2016 | 3 | 0 | 3 | | 2017 | 7 | 1 | 8 | | 2018 | 3 | 1 | 4 |
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Below are the most recent publications written about "Riboswitch" by people in Profiles.
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Braselmann E, Wierzba AJ, Polaski JT, Chrominski M, Holmes ZE, Hung ST, Batan D, Wheeler JR, Parker R, Jimenez R, Gryko D, Batey RT, Palmer AE. A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells. Nat Chem Biol. 2018 10; 14(10):964-971.
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Sherlock ME, Sudarsan N, Breaker RR. Riboswitches for the alarmone ppGpp expand the collection of RNA-based signaling systems. Proc Natl Acad Sci U S A. 2018 06 05; 115(23):6052-6057.
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Mirihana Arachchilage G, Sherlock ME, Weinberg Z, Breaker RR. SAM-VI RNAs selectively bind S-adenosylmethionine and exhibit similarities to SAM-III riboswitches. RNA Biol. 2018 03 04; 15(3):371-378.
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Greenlee EB, Stav S, Atilho RM, Brewer KI, Harris KA, Malkowski SN, Mirihana Arachchilage G, Perkins KR, Sherlock ME, Breaker RR. Challenges of ligand identification for the second wave of orphan riboswitch candidates. RNA Biol. 2018 03 04; 15(3):377-390.
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Polaski JT, Webster SM, Johnson JE, Batey RT. Cobalamin riboswitches exhibit a broad range of ability to discriminate between methylcobalamin and adenosylcobalamin. J Biol Chem. 2017 07 14; 292(28):11650-11658.
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McCown PJ, Corbino KA, Stav S, Sherlock ME, Breaker RR. Riboswitch diversity and distribution. RNA. 2017 07; 23(7):995-1011.
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Weinberg Z, Nelson JW, Lünse CE, Sherlock ME, Breaker RR. Bioinformatic analysis of riboswitch structures uncovers variant classes with altered ligand specificity. Proc Natl Acad Sci U S A. 2017 03 14; 114(11):E2077-E2085.
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Miao Z, Adamiak RW, Antczak M, Batey RT, Becka AJ, Biesiada M, Boniecki MJ, Bujnicki JM, Chen SJ, Cheng CY, Chou FC, Ferré-D'Amaré AR, Das R, Dawson WK, Ding F, Dokholyan NV, Dunin-Horkawicz S, Geniesse C, Kappel K, Kladwang W, Krokhotin A, Lach GE, Major F, Mann TH, Magnus M, Pachulska-Wieczorek K, Patel DJ, Piccirilli JA, Popenda M, Purzycka KJ, Ren A, Rice GM, Santalucia J, Sarzynska J, Szachniuk M, Tandon A, Trausch JJ, Tian S, Wang J, Weeks KM, Williams B, Xiao Y, Xu X, Zhang D, Zok T, Westhof E. RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme. RNA. 2017 05; 23(5):655-672.
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Porter EB, Polaski JT, Morck MM, Batey RT. Recurrent RNA motifs as scaffolds for genetically encodable small-molecule biosensors. Nat Chem Biol. 2017 03; 13(3):295-301.
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Sherlock ME, Malkowski SN, Breaker RR. Biochemical Validation of a Second Guanidine Riboswitch Class in Bacteria. Biochemistry. 2017 Jan 17; 56(2):352-358.
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