 Single Molecule Imaging
"Single Molecule Imaging" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
High resolution imaging techniques that allow visualization of individual molecules of proteins, lipids, or nucleic acids within cells or tissues.
| Descriptor ID |
D000072760
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| MeSH Number(s) |
E01.370.350.515.899 E01.370.350.557.750 E05.595.899 E05.601.555.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Single Molecule Imaging".
Below are MeSH descriptors whose meaning is more specific than "Single Molecule Imaging".
This graph shows the total number of publications written about "Single Molecule Imaging" by people in this website by year, and whether "Single Molecule Imaging" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 3 | 1 | 4 | | 2017 | 2 | 1 | 3 | | 2018 | 0 | 3 | 3 | | 2019 | 2 | 1 | 3 | | 2020 | 0 | 4 | 4 | | 2021 | 0 | 4 | 4 | | 2022 | 1 | 2 | 3 | | 2023 | 1 | 0 | 1 | | 2024 | 0 | 5 | 5 | | 2025 | 0 | 2 | 2 | | 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Single Molecule Imaging" by people in Profiles.
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Lee ES, Tommer ER, Rothman PB, Middleton SV, Youmans DT, Cech TR. Single-molecule tracking of DNMT1 in living cells reveals its cell cycle dynamics and its redistribution upon drug treatment. Nucleic Acids Res. 2026 Feb 05; 54(4).
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Archuleta SR, Miller RC, Mirita JA, Goodrich JA, Kugel JF. Single-molecule Microscopy Reveals That TFIIE Subunits Dynamically Interact With Preinitiation Complexes in a Manner Impacted by TFIIH. J Mol Biol. 2025 Dec 15; 437(24):169528.
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Rawson B, Yang Q, Catalano CE, Smith DE. Single-molecule measurements of bacteriophage lambda DNA packaging using purified terminase motor proteins and E. coli integration host factor. Sci Rep. 2025 Feb 27; 15(1):7093.
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Gentry RC, Ide NA, Comunale VM, Hartwick EW, Kinz-Thompson CD, Gonzalez RL. The mechanism of mRNA cap recognition. Nature. 2025 01; 637(8046):736-743.
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Pacheco J, Peña KA, Savransky S, Gidon A, Hammond GRV, Janetzko J, Vilardaga JP. Fast-diffusing receptor collisions with slow-diffusing peptide ligand assemble the ternary parathyroid hormone-GPCR-arrestin complex. Nat Commun. 2024 12 03; 15(1):10499.
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Owens MC, Shen H, Yanas A, Mendoza-Figueroa MS, Lavorando E, Wei X, Shweta H, Tang HY, Goldman YE, Liu KF. Specific catalytically impaired DDX3X mutants form sexually dimorphic hollow condensates. Nat Commun. 2024 11 05; 15(1):9553.
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McCombs AM, Armendariz JR, Falke JJ. Ras signaling mechanisms: New insights from single-molecule biophysics. Biophys J. 2024 10 01; 123(19):3277-3280.
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Harnik Y, Yakubovsky O, Hoefflin R, Novoselsky R, Bahar Halpern K, Barkai T, Korem Kohanim Y, Egozi A, Golani O, Addadi Y, Kedmi M, Keidar Haran T, Levin Y, Savidor A, Keren-Shaul H, Mayer C, Pencovich N, Pery R, Shouval DS, Tirosh I, Nachmany I, Itzkovitz S. A spatial expression atlas of the adult human proximal small intestine. Nature. 2024 08; 632(8027):1101-1109.
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Langeberg CJ, Kieft JS. A generalizable scaffold-based approach for structure determination of RNAs by cryo-EM. Nucleic Acids Res. 2023 11 10; 51(20):e100.
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Ingersoll S, Brown K, Ma B, Ren X. Quantifying the Binding and Target-Search Kinetics of Transcriptional Regulatory Factors by Live-Cell Single-Molecule Tracking. Methods Mol Biol. 2023; 2599:141-162.
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