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APOBEC-3G Deaminase

"APOBEC-3G Deaminase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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An APOBEC deaminase that functions as an inhibitor of RETROVIRIDAE replication and inhibits the mobility of RETROTRANSPOSONS via deaminase-dependent and independent mechanisms. It is selective for SINGLE-STRANDED DNA and does not deaminate double-stranded DNA or single or DOUBLE-STRANDED RNA. It exhibits potent antiviral activity against VIF PROTEIN deficient HIV-1 through the creation of hypermutations in the VIRAL DNA. It also has anti-viral activity against SIMIAN IMMUNODEFICIENCY VIRUSES and HEPATITIS B VIRUS.


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This graph shows the total number of publications written about "APOBEC-3G Deaminase" by people in this website by year, and whether "APOBEC-3G Deaminase" was a major or minor topic of these publications.
Bar chart showing 6 publications over 5 distinct years, with a maximum of 2 publications in 2010
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