 CCR5 Receptor Antagonists
"CCR5 Receptor Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds and drugs that inhibit or block the activity of CCR5 RECEPTORS.
| Descriptor ID |
D065100
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| MeSH Number(s) |
D27.505.519.275 D27.505.954.122.388.077.088.104
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| Concept/Terms |
CCR5 Receptor Antagonists- CCR5 Receptor Antagonists
- Antagonists, CCR5 Receptor
- Receptor Antagonists, CCR5
- CC Chemokine Receptor 5 Blockers
- Chemokine Co-receptor 5 Antagonists
- Chemokine Co receptor 5 Antagonists
- HIV-1 Fusion Coreceptor Antagonists
- HIV 1 Fusion Coreceptor Antagonists
- CC Chemokine Receptor 5 Antagonists
- CCR5 Receptor Blockers
- Blockers, CCR5 Receptor
- Receptor Blockers, CCR5
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Below are MeSH descriptors whose meaning is more general than "CCR5 Receptor Antagonists".
Below are MeSH descriptors whose meaning is more specific than "CCR5 Receptor Antagonists".
This graph shows the total number of publications written about "CCR5 Receptor Antagonists" by people in this website by year, and whether "CCR5 Receptor Antagonists" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "CCR5 Receptor Antagonists" by people in Profiles.
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Kelly KM, Tocchetti CG, Lyashkov A, Tarwater PM, Bedja D, Graham DR, Beck SE, Metcalf Pate KA, Queen SE, Adams RJ, Paolocci N, Mankowski JL. CCR5 inhibition prevents cardiac dysfunction in the SIV/macaque model of HIV. J Am Heart Assoc. 2014 Apr 02; 3(2):e000874.
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Kelly KM, Beck SE, Metcalf Pate KA, Queen SE, Dorsey JL, Adams RJ, Avery LB, Hubbard W, Tarwater PM, Mankowski JL. Neuroprotective maraviroc monotherapy in simian immunodeficiency virus-infected macaques: reduced replicating and latent SIV in the brain. AIDS. 2013 Nov 28; 27(18):F21-8.
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Neff CP, Kurisu T, Ndolo T, Fox K, Akkina R. A topical microbicide gel formulation of CCR5 antagonist maraviroc prevents HIV-1 vaginal transmission in humanized RAG-hu mice. PLoS One. 2011; 6(6):e20209.
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Matalon S, Palmer BE, Nold MF, Furlan A, Kassu A, Fossati G, Mascagni P, Dinarello CA. The histone deacetylase inhibitor ITF2357 decreases surface CXCR4 and CCR5 expression on CD4(+) T-cells and monocytes and is superior to valproic acid for latent HIV-1 expression in vitro. J Acquir Immune Defic Syndr. 2010 May 01; 54(1):1-9.
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Anderson J, Akkina R. CXCR4 and CCR5 shRNA transgenic CD34+ cell derived macrophages are functionally normal and resist HIV-1 infection. Retrovirology. 2005 Aug 18; 2:53.
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Bai J, Gorantla S, Banda N, Cagnon L, Rossi J, Akkina R. Characterization of anti-CCR5 ribozyme-transduced CD34+ hematopoietic progenitor cells in vitro and in a SCID-hu mouse model in vivo. Mol Ther. 2000 Mar; 1(3):244-54.
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