An EGF family member that is expressed in a variety of hematopoietic, endothelial, vascular smooth muscle, and epithelial cells. It is synthesized as a transmembrane protein which is cleaved by proteases to produce the secreted form of the protein which has specificity for the EGF RECEPTOR and the ERBB-4 RECEPTOR. The membrane-bound form of the protein has been identified as the receptor which binds to and allows DIPHTHERIA TOXIN to enter cells.

Descriptor ID	D066257
MeSH Number(s)	D12.644.276.382.625 D12.776.467.382.625 D23.529.382.625
Concept/Terms	Heparin-binding EGF-like Growth Factor Heparin-binding EGF-like Growth Factor Heparin binding EGF like Growth Factor HB-EGF HB EGF Heparin-binding EGF-like Growth-Factor Short Form HB-EGF Short Form HB-EGF HB-EGF, Short Form Short Form HB EGF SF HB-EGF SF HB EGF Heparin-binding Epidermal Growth Factor-like Growth Factor Precursor Protein Heparin-binding Epidermal Growth Factor-like Growth Factor Precursor Protein Heparin binding Epidermal Growth Factor like Growth Factor Precursor Protein Receptor, Diphtheria Toxin HB-EGF Precursor HB EGF Precursor Diphtheria Toxin Receptor Toxin Receptor, Diphtheria Diphtheria Toxin Receptors Receptors, Diphtheria Toxin Toxin Receptors, Diphtheria

Below are MeSH descriptors whose meaning is more general than "Heparin-binding EGF-like Growth Factor".

Below are MeSH descriptors whose meaning is related to "Heparin-binding EGF-like Growth Factor".

Below are MeSH descriptors whose meaning is more specific than "Heparin-binding EGF-like Growth Factor".