 V(D)J Recombination
"V(D)J Recombination" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process by which the V (variable), D (diversity), and J (joining) segments of IMMUNOGLOBULIN GENES or T-CELL RECEPTOR GENES are assembled during the development of LYMPHOID CELLS using NONHOMOLOGOUS DNA END-JOINING.
| Descriptor ID |
D060152
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| MeSH Number(s) |
G05.344.900 G05.728.932
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| Concept/Terms |
V(D)J Recombination- V(D)J Recombination
- VDJ Recombination
- Recombination, VDJ
- Recombinations, VDJ
- VDJ Recombinations
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Below are MeSH descriptors whose meaning is more general than "V(D)J Recombination".
Below are MeSH descriptors whose meaning is more specific than "V(D)J Recombination".
This graph shows the total number of publications written about "V(D)J Recombination" by people in this website by year, and whether "V(D)J Recombination" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "V(D)J Recombination" by people in Profiles.
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Hagman JR, Arends T, Laborda C, Knapp JR, Harmacek L, O'Connor BP. Chromodomain helicase DNA-binding 4 (CHD4) regulates early B cell identity and V(D)J recombination. Immunol Rev. 2022 01; 305(1):29-42.
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Chen JW, Rice TA, Bannock JM, Bielecka AA, Strauss JD, Catanzaro JR, Wang H, Menard LC, Anolik JH, Palm NW, Meffre E. Autoreactivity in na?ve human fetal B cells is associated with commensal bacteria recognition. Science. 2020 07 17; 369(6501):320-325.
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Yeap LS, Hwang JK, Du Z, Meyers RM, Meng FL, Jakubauskaite A, Liu M, Mani V, Neuberg D, Kepler TB, Wang JH, Alt FW. Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody Genes. Cell. 2015 Nov 19; 163(5):1124-1137.
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Clambey ET, Davenport B, Kappler JW, Marrack P, Homann D. Molecules in medicine mini review: the a? T cell receptor. J Mol Med (Berl). 2014 Jul; 92(7):735-41.
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Champagne DP, Shockett PE. Illegitimate V(D)J recombination-mediated deletions in Notch1 and Bcl11b are not sufficient for extensive clonal expansion and show minimal age or sex bias in frequency or junctional processing. Mutat Res. 2014 Mar; 761:34-48.
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Gopalakrishnan S, Majumder K, Predeus A, Huang Y, Koues OI, Verma-Gaur J, Loguercio S, Su AI, Feeney AJ, Artyomov MN, Oltz EM. Unifying model for molecular determinants of the preselection V? repertoire. Proc Natl Acad Sci U S A. 2013 Aug 20; 110(34):E3206-15.
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