 Protein Domains
"Protein Domains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Discrete protein structural units that may fold independently of the rest of the protein and have their own functions.
| Descriptor ID |
D000072417
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| MeSH Number(s) |
G02.111.570.820.709.275.750 G02.111.570.820.709.610.500
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| Concept/Terms |
Protein Domains- Protein Domains
- Peptide Domain
- Domain, Peptide
- Domains, Peptide
- Peptide Domains
- Protein Domain
- Domain, Protein
- Domains, Protein
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Below are MeSH descriptors whose meaning is more general than "Protein Domains".
Below are MeSH descriptors whose meaning is more specific than "Protein Domains".
This graph shows the total number of publications written about "Protein Domains" by people in this website by year, and whether "Protein Domains" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 2 | 2 | | 2016 | 0 | 21 | 21 | | 2017 | 0 | 19 | 19 | | 2018 | 4 | 14 | 18 | | 2019 | 2 | 25 | 27 | | 2020 | 1 | 15 | 16 | | 2021 | 3 | 14 | 17 | | 2022 | 1 | 8 | 9 | | 2023 | 0 | 5 | 5 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Domains" by people in Profiles.
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Potter SC, Gibbs BE, Hammel FA, Joiner CM, Paulo JA, Janetzko J, Levine ZG, Fei GQ, Haggarty SJ, Walker S. Dissecting OGT's TPR domain to identify determinants of cellular function. Proc Natl Acad Sci U S A. 2024 May 28; 121(22):e2401729121.
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Upadhyay V, Panja S, Lucas A, Patrick C, Mallela KMG. Biophysical evolution of the receptor-binding domains of SARS-CoVs. Biophys J. 2023 12 05; 122(23):4489-4502.
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Nawarathnage S, Tseng YJ, Soleimani S, Smith T, Pedroza Romo MJ, Abiodun WO, Egbert CM, Madhusanka D, Bunn D, Woods B, Tsubaki E, Stewart C, Brown S, Doukov T, Andersen JL, Moody JD. Fusion crystallization reveals the behavior of both the 1TEL crystallization chaperone and the TNK1?UBA domain. Structure. 2023 12 07; 31(12):1589-1603.e6.
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Klontz E, Obi JO, Wang Y, Glendening G, Carr J, Tsibouris C, Buddula S, Nallar S, Soares AS, Beckett D, Redzic JS, Eisenmesser E, Palm C, Schmidt K, Scudder AH, Obiorah T, Essuman K, Milbrandt J, Diantonio A, Ray K, Snyder MLD, Deredge D, Snyder GA. The structure of NAD+ consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations. J Biol Chem. 2023 11; 299(11):105290.
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Song R, Zhang J, Perszyk RE, Camp CR, Tang W, Kannan V, Li J, Xu Y, Chen J, Li Y, Liang SH, Traynelis SF, Yuan H. Differential responses of disease-related GRIN variants located in pore-forming M2 domain of N-methyl-D-aspartate receptor to FDA-approved inhibitors. J Neurochem. 2024 Dec; 168(12):3936-3949.
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von der Malsburg A, Sapp GM, Zuccaro KE, von Appen A, Moss FR, Kalia R, Bennett JA, Abriata LA, Dal Peraro M, van der Laan M, Frost A, Aydin H. Structural mechanism of mitochondrial membrane remodelling by human OPA1. Nature. 2023 Aug; 620(7976):1101-1108.
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Langeberg CJ, Nichols PJ, Henen MA, Vicens Q, V?geli B. Differential Structural Features of Two Mutant ADAR1p150 Za Domains Associated with Aicardi-Gouti?res Syndrome. J Mol Biol. 2023 04 15; 435(8):168040.
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Pacheco A, Issaian A, Davis J, Anderson N, Nemkov T, Paukovich N, Henen MA, V?geli B, Sikela JM, Hansen K. Proteolytic activation of human-specific Olduvai domains by the furin protease. Int J Biol Macromol. 2023 Apr 15; 234:123041.
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Penumutchu S, Liu J, Singh UK, Kutateladze TG, Zhang Y. Protocol to identify drug-binding sites in proteins using solution NMR spectroscopy. STAR Protoc. 2022 12 16; 3(4):101842.
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Born A, Soetbeer J, Henen MA, Breitgoff F, Polyhach Y, Jeschke G, V?geli B. Ligand-specific conformational change drives interdomain allostery in Pin1. Nat Commun. 2022 08 04; 13(1):4546.
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