 Carbonic Anhydrase IX
"Carbonic Anhydrase IX" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A carbonic anhydrase and transmembrane protein that consists of an N-terminal PROTEOGLYCAN-like domain, a catalytic region, a single-pass transmembrane domain, and a short intracellular tail. It functions as a dimer and is expressed primarily by cells of the GASTROINTESTINAL TRACT; BILE DUCT EPITHELIUM; and GALL BLADDER. It is expressed at high levels in many solid tumors, especially CLEAR CELL RENAL CARCINOMA, in response to CELL HYPOXIA.
| Descriptor ID |
D000071231
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| MeSH Number(s) |
D08.811.520.241.300.150.450 D12.776.543.178 D23.050.285.196
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Carbonic Anhydrase IX".
Below are MeSH descriptors whose meaning is more specific than "Carbonic Anhydrase IX".
This graph shows the total number of publications written about "Carbonic Anhydrase IX" by people in this website by year, and whether "Carbonic Anhydrase IX" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Carbonic Anhydrase IX" by people in Profiles.
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Sena JA, Wang L, Hu CJ. BRG1 and BRM chromatin-remodeling complexes regulate the hypoxia response by acting as coactivators for a subset of hypoxia-inducible transcription factor target genes. Mol Cell Biol. 2013 Oct; 33(19):3849-63.
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Le QT, Chen E, Salim A, Cao H, Kong CS, Whyte R, Donington J, Cannon W, Wakelee H, Tibshirani R, Mitchell JD, Richardson D, O'Byrne KJ, Koong AC, Giaccia AJ. An evaluation of tumor oxygenation and gene expression in patients with early stage non-small cell lung cancers. Clin Cancer Res. 2006 Mar 01; 12(5):1507-14.
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Grabmaier K, Vissers JL, De Weijert MC, Oosterwijk-Wakka JC, Van Bokhoven A, Brakenhoff RH, Noessner E, Mulders PA, Merkx G, Figdor CG, Adema GJ, Oosterwijk E. Molecular cloning and immunogenicity of renal cell carcinoma-associated antigen G250. Int J Cancer. 2000 Mar 15; 85(6):865-70.
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