 Autophagy-Related Protein 7
"Autophagy-Related Protein 7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autophagy related protein that is similar to UBIQUITIN-ACTIVATING ENZYME E1. It functions in CYTOPLASM to VACUOLE transport (Cvt) and AUTOPHAGY by activating ATG12 PROTEIN for its conjugation with ATG5 PROTEIN, as well as the conjugation of ATG8 FAMILY PROTEINS with phosphatidylethanolamine for ATG8 association to Cvt vesicles and AUTOPHAGOSOME membranes. It is also required for the nitrogen starvation response in yeast, MITOPHAGY; and autophagic cell death induced by CASPASE 8 inhibition.
| Descriptor ID |
D000071193
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| MeSH Number(s) |
D12.776.094.399
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| Concept/Terms |
Autophagy-Related Protein 7- Autophagy-Related Protein 7
- Autophagy Related Protein 7
- ATG7 Protein
- Ubiquitin-Activating Enzyme E1-like Protein
- Ubiquitin Activating Enzyme E1 like Protein
- Ubiquitin-Like Modifier-Activating Enzyme ATG7
- Ubiquitin Like Modifier Activating Enzyme ATG7
- ATG12-Activating Enzyme E1 ATG7
- ATG12 Activating Enzyme E1 ATG7
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Below are MeSH descriptors whose meaning is more general than "Autophagy-Related Protein 7".
Below are MeSH descriptors whose meaning is more specific than "Autophagy-Related Protein 7".
This graph shows the total number of publications written about "Autophagy-Related Protein 7" by people in this website by year, and whether "Autophagy-Related Protein 7" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 | | 2016 | 0 | 2 | 2 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Autophagy-Related Protein 7" by people in Profiles.
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Towers CG, Wodetzki DK, Thorburn J, Smith KR, Caino MC, Thorburn A. Mitochondrial-derived vesicles compensate for loss of LC3-mediated mitophagy. Dev Cell. 2021 07 26; 56(14):2029-2042.e5.
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Towers CG, Fitzwalter BE, Regan D, Goodspeed A, Morgan MJ, Liu CW, Gustafson DL, Thorburn A. Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition. Dev Cell. 2019 09 23; 50(6):690-703.e6.
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Merves JF, Whelan KA, Benitez AJ, Muir AB, Furuta GT, Wang ML, Falk GW, Spergel JM, Nakagawa H. ATG7 Gene Expression as a Novel Tissue Biomarker in Eosinophilic Esophagitis. Am J Gastroenterol. 2016 Jan; 111(1):151-3.
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Rangarajan S, Kurundkar A, Kurundkar D, Bernard K, Sanders YY, Ding Q, Antony VB, Zhang J, Zmijewski J, Thannickal VJ. Novel Mechanisms for the Antifibrotic Action of Nintedanib. Am J Respir Cell Mol Biol. 2016 Jan; 54(1):51-9.
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Maycotte P, Jones KL, Goodall ML, Thorburn J, Thorburn A. Autophagy Supports Breast Cancer Stem Cell Maintenance by Regulating IL6 Secretion. Mol Cancer Res. 2015 Apr; 13(4):651-8.
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Maycotte P, Gearheart CM, Barnard R, Aryal S, Mulcahy Levy JM, Fosmire SP, Hansen RJ, Morgan MJ, Porter CC, Gustafson DL, Thorburn A. STAT3-mediated autophagy dependence identifies subtypes of breast cancer where autophagy inhibition can be efficacious. Cancer Res. 2014 May 01; 74(9):2579-90.
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Hagiwara S, Iwasaka H, Hasegawa A, Kudo K, Kusaka J, Oyama Y, Noguchi T. Infusion of a glucose solution reduces autophagy in the liver after LPS-induced systemic inflammation. Inflammation. 2012 Feb; 35(1):249-58.
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Levy JM, Thorburn A. Modulation of pediatric brain tumor autophagy and chemosensitivity. J Neurooncol. 2012 Jan; 106(2):281-90.
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Roberts P, Moshitch-Moshkovitz S, Kvam E, O'Toole E, Winey M, Goldfarb DS. Piecemeal microautophagy of nucleus in Saccharomyces cerevisiae. Mol Biol Cell. 2003 Jan; 14(1):129-41.
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