 Receptor for Advanced Glycation End Products
"Receptor for Advanced Glycation End Products" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A single-pass transmembrane CELL SURFACE RECEPTOR that binds ADVANCED GLYCATION END PRODUCTS to mediate cellular responses to both acute and chronic vascular inflammation in conditions such as ATHEROSCLEROSIS and DIABETES MELLITUS, TYPE 2. It also binds AMYLOID BETA PEPTIDES and the ALARMINS - S100A12 and S100 CALCIUM BINDING PROTEIN BETA SUBUNIT.
| Descriptor ID |
D000067759
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| MeSH Number(s) |
D12.776.543.750.615
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| Concept/Terms |
Receptor for Advanced Glycation End Products- Receptor for Advanced Glycation End Products
- AGE Receptor
- Receptor, AGE
- RAGE (Receptor for Advanced Glycation End Products)
- Advanced Glycosylation End Product Receptors
- Advanced Glycosylation End-Product Receptor
- Advanced Glycosylation End Product Receptor
- Advanced Glycosylation End-Product Receptors
- Advanced Glycosylation Endproduct Receptors
- Receptor for Advanced Glycation End Products (RAGE)
- Receptor for Advanced Glycation Endproducts
- Receptor, Advanced Glycosylation End-Product
- Receptor, Advanced Glycosylation End Product
- Receptor, Advanced Glycosylation End-Products
- Receptor, Advanced Glycosylation End Products
- Advanced Glycosylation End Product-Specific Receptor
- Advanced Glycosylation End Product Specific Receptor
- AGER Protein
- Protein, AGER
- Amphoterin Receptor
- Receptor, Amphoterin
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Below are MeSH descriptors whose meaning is more general than "Receptor for Advanced Glycation End Products".
Below are MeSH descriptors whose meaning is more specific than "Receptor for Advanced Glycation End Products".
This graph shows the total number of publications written about "Receptor for Advanced Glycation End Products" by people in this website by year, and whether "Receptor for Advanced Glycation End Products" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 1 | 2 | | 2015 | 0 | 3 | 3 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 2 | 1 | 3 | | 2019 | 2 | 0 | 2 | | 2020 | 0 | 1 | 1 | | 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Receptor for Advanced Glycation End Products" by people in Profiles.
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Nam MH, Pantcheva MB, Rankenberg J, Nagaraj RH. Transforming growth factor-ß2-mediated mesenchymal transition in lens epithelial cells is repressed in the absence of RAGE. Biochem J. 2021 06 25; 478(12):2285-2296.
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Pratte KA, Curtis JL, Kechris K, Couper D, Cho MH, Silverman EK, DeMeo DL, Sciurba FC, Zhang Y, Ortega VE, O'Neal WK, Gillenwater LA, Lynch DA, Hoffman EA, Newell JD, Comellas AP, Castaldi PJ, Miller BE, Pouwels SD, Hacken NHTT, Bischoff R, Klont F, Woodruff PG, Paine R, Barr RG, Hoidal J, Doerschuk CM, Charbonnier JP, Sung R, Locantore N, Yonchuk JG, Jacobson S, Tal-Singer R, Merrill D, Bowler RP. Soluble receptor for advanced glycation end products (sRAGE) as a biomarker of COPD. Respir Res. 2021 Apr 27; 22(1):127.
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Railwah C, Lora A, Zahid K, Goldenberg H, Campos M, Wyman A, Jundi B, Ploszaj M, Rivas M, Dabo A, Majka SM, Foronjy R, El Gazzar M, Geraghty P. Cigarette smoke induction of S100A9 contributes to chronic obstructive pulmonary disease. Am J Physiol Lung Cell Mol Physiol. 2020 12 01; 319(6):L1021-L1035.
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Hurtado Del Pozo C, Ruiz HH, Arivazhagan L, Aranda JF, Shim C, Daya P, Derk J, MacLean M, He M, Frye L, Friedline RH, Noh HL, Kim JK, Friedman RA, Ramasamy R, Schmidt AM. A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis. Cell Rep. 2019 07 16; 28(3):773-791.e7.
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MacLean M, Derk J, Ruiz HH, Juranek JK, Ramasamy R, Schmidt AM. The Receptor for Advanced Glycation End Products (RAGE) and DIAPH1: Implications for vascular and neuroinflammatory dysfunction in disorders of the central nervous system. Neurochem Int. 2019 06; 126:154-164.
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Abedini A, Derk J, Schmidt AM. The receptor for advanced glycation endproducts is a mediator of toxicity by IAPP and other proteotoxic aggregates: Establishing and exploiting common ground for novel amyloidosis therapies. Protein Sci. 2018 07; 27(7):1166-1180.
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Abedini A, Cao P, Plesner A, Zhang J, He M, Derk J, Patil SA, Rosario R, Lonier J, Song F, Koh H, Li H, Raleigh DP, Schmidt AM. RAGE binds preamyloid IAPP intermediates and mediates pancreatic ß cell proteotoxicity. J Clin Invest. 2018 02 01; 128(2):682-698.
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Derk J, Bermudez Hernandez K, Rodriguez M, He M, Koh H, Abedini A, Li H, Fenyö D, Schmidt AM. Diaphanous 1 (DIAPH1) is Highly Expressed in the Aged Human Medial Temporal Cortex and Upregulated in Myeloid Cells During Alzheimer's Disease. J Alzheimers Dis. 2018; 64(3):995-1007.
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Manichaikul A, Sun L, Borczuk AC, Onengut-Gumuscu S, Farber EA, Mathai SK, Zhang W, Raghu G, Kaufman JD, Hinckley-Stukovsky KD, Kawut SM, Jelic S, Liu W, Fingerlin TE, Schwartz DA, Sell JL, Rich SS, Barr RG, Lederer DJ. Plasma Soluble Receptor for Advanced Glycation End Products in Idiopathic Pulmonary Fibrosis. Ann Am Thorac Soc. 2017 May; 14(5):628-635.
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Raghavan CT, Nagaraj RH. AGE-RAGE interaction in the TGFß2-mediated epithelial to mesenchymal transition of human lens epithelial cells. Glycoconj J. 2016 08; 33(4):631-43.
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