 Interleukin-33
"Interleukin-33" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the INTERLEUKIN-1 protein family involved in the maturation of TH2 CELLS and the activation of MAST CELLS; BASOPHILS; EOSINOPHILS and NK CELLS. It is also produced by ENDOTHELIAL CELLS; EPITHELIAL CELLS and FIBROBLASTS; where it can function as an alarmin to modulate immune and inflammatory responses to tissue damage.
| Descriptor ID |
D000067596
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| MeSH Number(s) |
D12.644.276.374.465.850 D12.776.467.374.465.850 D23.529.374.465.850
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Interleukin-33".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-33".
This graph shows the total number of publications written about "Interleukin-33" by people in this website by year, and whether "Interleukin-33" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 1 | 3 | 4 | | 2016 | 1 | 1 | 2 | | 2017 | 2 | 3 | 5 | | 2018 | 0 | 2 | 2 | | 2019 | 0 | 4 | 4 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interleukin-33" by people in Profiles.
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Berman R, Kopf KW, Min E, Huang J, Downey GP, Alam R, Chu HW, Day BJ. IL-33/ST2 signaling modulates Afghanistan particulate matter induced airway hyperresponsiveness in mice. Toxicol Appl Pharmacol. 2020 10 01; 404:115186.
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Rangarajan S, Thannickal VJ. Remember Me? The Bone Marrow in Pulmonary Fibrosis. Am J Respir Crit Care Med. 2019 10 15; 200(8):959-960.
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Højen JF, Kristensen MLV, McKee AS, Wade MT, Azam T, Lunding LP, de Graaf DM, Swartzwelter BJ, Wegmann M, Tolstrup M, Beckman K, Fujita M, Fischer S, Dinarello CA. IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease. Nat Immunol. 2019 09; 20(9):1138-1149.
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Schaunaman N, Sanchez A, Dimasuay KG, Pavelka N, Numata M, Alam R, Martin RJ, Chu HW. Interleukin 1 Receptor-Like 1 (IL1RL1) Promotes Airway Bacterial and Viral Infection and Inflammation. Infect Immun. 2019 07; 87(7).
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Cho HS, Reboldi A, Hall JA, Berg LJ. The Tec kinase ITK is essential for ILC2 survival and epithelial integrity in the intestine. Nat Commun. 2019 02 15; 10(1):784.
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Ito Y, Schaefer N, Sanchez A, Francisco D, Alam R, Martin RJ, Ledford JG, Stevenson C, Jiang D, Li L, Kraft M, Chu HW. Toll-Interacting Protein, Tollip, Inhibits IL-13-Mediated Pulmonary Eosinophilic Inflammation in Mice. J Innate Immun. 2018; 10(2):106-118.
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Dinarello CA. Overview of the IL-1 family in innate inflammation and acquired immunity. Immunol Rev. 2018 01; 281(1):8-27.
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Verma M, Liu S, Michalec L, Sripada A, Gorska MM, Alam R. Experimental asthma persists in IL-33 receptor knockout mice because of the emergence of thymic stromal lymphopoietin-driven IL-9+ and IL-13+ type 2 innate lymphoid cell subpopulations. J Allergy Clin Immunol. 2018 09; 142(3):793-803.e8.
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Ravichandran K, Holditch S, Brown CN, Wang Q, Ozkok A, Weiser-Evans MC, Nemenoff R, Miyazaki M, Thiessen-Philbrook H, Parikh CR, Ljubanovic D, Edelstein CL. IL-33 deficiency slows cancer growth but does not protect against cisplatin-induced AKI in mice with cancer. Am J Physiol Renal Physiol. 2018 03 01; 314(3):F356-F366.
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Gaurav R, Varasteh JT, Weaver MR, Jacobson SR, Hernandez-Lagunas L, Liu Q, Nozik-Grayck E, Chu HW, Alam R, Nordestgaard BG, Kobylecki CJ, Afzal S, Chupp GL, Bowler RP. The R213G polymorphism in SOD3 protects against allergic airway inflammation. JCI Insight. 2017 09 07; 2(17).
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