 Replication Protein A
"Replication Protein A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A single-stranded DNA-binding protein that is found in EUKARYOTIC CELLS. It is required for DNA REPLICATION; DNA REPAIR; and GENETIC RECOMBINATION.
| Descriptor ID |
D051716
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| MeSH Number(s) |
D12.776.260.700
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| Concept/Terms |
Replication Protein A- Replication Protein A
- Single-Strand Binding Protein RP-A
- Single Strand Binding Protein RP A
- Replication Factor A Single-Stranded DNA-Binding Protein
- Replication Factor A Single Stranded DNA Binding Protein
- Replication Factor A
- DNA Replication Factor A
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Below are MeSH descriptors whose meaning is more general than "Replication Protein A".
Below are MeSH descriptors whose meaning is more specific than "Replication Protein A".
This graph shows the total number of publications written about "Replication Protein A" by people in this website by year, and whether "Replication Protein A" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2020 | 1 | 1 | 2 | | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Replication Protein A" by people in Profiles.
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Wieser TA, Wuttke DS. Replication Protein A Utilizes Differential Engagement of Its DNA-Binding Domains to Bind Biologically Relevant ssDNAs in Diverse Binding Modes. Biochemistry. 2022 11 15; 61(22):2592-2606.
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Peters DK, Erickson KD, Garcea RL. Live Cell Microscopy of Murine Polyomavirus Subnuclear Replication Centers. Viruses. 2020 10 02; 12(10).
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Lim CJ, Barbour AT, Zaug AJ, Goodrich KJ, McKay AE, Wuttke DS, Cech TR. The structure of human CST reveals a decameric assembly bound to telomeric DNA. Science. 2020 06 05; 368(6495):1081-1085.
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Peters DK, Garcea RL. Murine polyomavirus DNA transitions through spatially distinct nuclear replication subdomains during infection. PLoS Pathog. 2020 03; 16(3):e1008403.
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Zaaijer S, Shaikh N, Nageshan RK, Cooper JP. Rif1 Regulates the Fate of DNA Entanglements during Mitosis. Cell Rep. 2016 06 28; 16(1):148-160.
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Ashley AK, Shrivastav M, Nie J, Amerin C, Troksa K, Glanzer JG, Liu S, Opiyo SO, Dimitrova DD, Le P, Sishc B, Bailey SM, Oakley GG, Nickoloff JA. DNA-PK phosphorylation of RPA32 Ser4/Ser8 regulates replication stress checkpoint activation, fork restart, homologous recombination and mitotic catastrophe. DNA Repair (Amst). 2014 Sep; 21:131-9.
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Chen P, O'Neal JF, Ebelt ND, Cantrell MA, Mitra S, Nasrazadani A, Vandenbroek TL, Heasley LE, Van Den Berg CL. Jnk2 effects on tumor development, genetic instability and replicative stress in an oncogene-driven mouse mammary tumor model. PLoS One. 2010 May 03; 5(5):e10443.
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Gelinas AD, Paschini M, Reyes FE, H?roux A, Batey RT, Lundblad V, Wuttke DS. Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain. Proc Natl Acad Sci U S A. 2009 Nov 17; 106(46):19298-303.
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Shell SM, Hess S, Kvaratskhelia M, Zou Y. Mass spectrometric identification of lysines involved in the interaction of human replication protein a with single-stranded DNA. Biochemistry. 2005 Jan 25; 44(3):971-8.
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