 Interleukin-4
"Interleukin-4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells.
| Descriptor ID |
D015847
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| MeSH Number(s) |
D12.644.276.374.465.186 D12.776.467.374.465.178 D23.529.374.465.186
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| Concept/Terms |
Interleukin-4- Interleukin-4
- Interleukin 4
- B-Cell Growth Factor-1
- B Cell Growth Factor 1
- B-Cell Growth Factor-I
- B Cell Growth Factor I
- B-Cell Proliferating Factor
- B Cell Proliferating Factor
- B-Cell Stimulating Factor-1
- B Cell Stimulating Factor 1
- B-Cell Stimulatory Factor 1
- B-Cell Stimulatory Factor-1
- BCGF-1
- Binetrakin
- BSF-1
- IL-4
- IL4
- Mast Cell Growth Factor-2
- Mast Cell Growth Factor 2
- MCGF-2
- B Cell Stimulatory Factor-1
- B Cell Stimulatory Factor 1
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Below are MeSH descriptors whose meaning is more general than "Interleukin-4".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-4".
This graph shows the total number of publications written about "Interleukin-4" by people in this website by year, and whether "Interleukin-4" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 1 | 1 | 2 | | 1991 | 1 | 1 | 2 | | 1992 | 3 | 0 | 3 | | 1993 | 1 | 0 | 1 | | 1994 | 1 | 2 | 3 | | 1995 | 2 | 2 | 4 | | 1996 | 3 | 1 | 4 | | 1997 | 2 | 4 | 6 | | 1998 | 2 | 4 | 6 | | 1999 | 1 | 3 | 4 | | 2000 | 3 | 2 | 5 | | 2001 | 1 | 2 | 3 | | 2002 | 2 | 6 | 8 | | 2003 | 5 | 2 | 7 | | 2004 | 5 | 3 | 8 | | 2005 | 1 | 4 | 5 | | 2006 | 3 | 2 | 5 | | 2007 | 1 | 3 | 4 | | 2008 | 3 | 6 | 9 | | 2009 | 3 | 3 | 6 | | 2010 | 1 | 7 | 8 | | 2011 | 2 | 1 | 3 | | 2012 | 0 | 4 | 4 | | 2013 | 2 | 7 | 9 | | 2014 | 3 | 4 | 7 | | 2015 | 3 | 8 | 11 | | 2016 | 0 | 3 | 3 | | 2017 | 0 | 1 | 1 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 2 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Interleukin-4" by people in Profiles.
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Boorgula MP, Taub MA, Rafaels N, Daya M, Campbell M, Chavan S, Shetty A, Cheadle C, Barkataki S, Fan J, David G, Beaty TH, Ruczinski I, Hanifin J, Schneider LC, Gallo RL, Paller AS, Beck LA, Leung DY, Mathias RA, Barnes KC. Replicated methylation changes associated with eczema herpeticum and allergic response. Clin Epigenetics. 2019 08 23; 11(1):122.
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Phalke SP, Huang Y, Rubtsova K, Getahun A, Sun D, Reinhardt RL, O'Brien RL, Born WK. ?d T cells shape memory-phenotype aß T cell populations in non-immunized mice. PLoS One. 2019; 14(6):e0218827.
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Svedberg FR, Brown SL, Krauss MZ, Campbell L, Sharpe C, Clausen M, Howell GJ, Clark H, Madsen J, Evans CM, Sutherland TE, Ivens AC, Thornton DJ, Grencis RK, Hussell T, Cunoosamy DM, Cook PC, MacDonald AS. The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation. Nat Immunol. 2019 05; 20(5):571-580.
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Berdyshev E, Goleva E, Bronova I, Dyjack N, Rios C, Jung J, Taylor P, Jeong M, Hall CF, Richers BN, Norquest KA, Zheng T, Seibold MA, Leung DY. Lipid abnormalities in atopic skin are driven by type 2 cytokines. JCI Insight. 2018 02 22; 3(4).
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Dell'Aringa M, Reinhardt RL, Friedman RS, Jacobelli J. Live Imaging of IL-4-Expressing T Follicular Helper Cells in Explanted Lymph Nodes. Methods Mol Biol. 2018; 1799:225-235.
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Schwartzbaum J, Wang M, Root E, Pietrzak M, Rempala GA, Huang RP, Johannesen TB, Grimsrud TK. A nested case-control study of 277 prediagnostic serum cytokines and glioma. PLoS One. 2017; 12(6):e0178705.
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Coleman SL, Kruger MC, Sawyer GM, Hurst RD. Procyanidin A2 Modulates IL-4-Induced CCL26 Production in Human Alveolar Epithelial Cells. Int J Mol Sci. 2016 Nov 12; 17(11).
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Stover K, Fukuyama T, Young AT, Daniele MA, Oberley R, Crapo JD, Bäumer W. Topically applied manganese-porphyrins BMX-001 and BMX-010 display a significant anti-inflammatory response in a mouse model of allergic dermatitis. Arch Dermatol Res. 2016 Dec; 308(10):711-721.
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Jiang F, He J, Navarro-Alvarez N, Xu J, Li X, Li P, Wu W. Elongation Factor Tu and Heat Shock Protein 70 Are Membrane-Associated Proteins from Mycoplasma ovipneumoniae Capable of Inducing Strong Immune Response in Mice. PLoS One. 2016; 11(8):e0161170.
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Born WK, Huang Y, Zeng W, Torres RM, O'Brien RL. A Special Connection between ?d T Cells and Natural Antibodies? Arch Immunol Ther Exp (Warsz). 2016 Dec; 64(6):455-462.
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