 Mucociliary Clearance
"Mucociliary Clearance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-specific host defense mechanism that removes MUCUS and other material from the LUNGS by ciliary and secretory activity of the tracheobronchial submucosal glands. It is measured in vivo as mucus transfer, ciliary beat frequency, and clearance of radioactive tracers.
| Descriptor ID |
D009079
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| MeSH Number(s) |
E01.370.386.520 G09.772.555
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| Concept/Terms |
Mucociliary Clearance- Mucociliary Clearance
- Clearance, Mucociliary
- Clearances, Mucociliary
- Mucociliary Clearances
- Mucociliary Transport
- Mucociliary Transports
- Transport, Mucociliary
- Transports, Mucociliary
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Below are MeSH descriptors whose meaning is more general than "Mucociliary Clearance".
Below are MeSH descriptors whose meaning is more specific than "Mucociliary Clearance".
This graph shows the total number of publications written about "Mucociliary Clearance" by people in this website by year, and whether "Mucociliary Clearance" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 3 | 0 | 3 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 3 | 4 | | 2015 | 0 | 1 | 1 | | 2016 | 2 | 1 | 3 | | 2018 | 3 | 1 | 4 | | 2020 | 1 | 0 | 1 | | 2021 | 2 | 0 | 2 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mucociliary Clearance" by people in Profiles.
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Guntur VP, Manka LA, Moore CM, Wynn E, Vladar EK, Alam R, Pham TH, Fingerlin TE, Martin RJ. Refractory neutrophilic asthma and ciliary genes. J Allergy Clin Immunol. 2022 06; 149(6):1970-1980.
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Donaldson SH, Laube BL, Mogayzel P, Corcoran TE, Pilewski JM, Ceppe A, Wu J, Bhambhvani PG, Ratjen F, Sagel SD, Clancy JP, Rowe SM, Bennett WD. Effect of lumacaftor-ivacaftor on mucociliary clearance and clinical outcomes in cystic fibrosis: Results from the PROSPECT MCC sub-study. J Cyst Fibros. 2022 01; 21(1):143-145.
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Laube BL, Carson KA, Evans CM, Aksit MA, Collaco JM, Richardson VL, Sharpless G, Zeitlin PL, Cutting GR, Mogayzel PJ. Characterizing mucociliary clearance in young children with cystic fibrosis. Pediatr Res. 2022 02; 91(3):612-620.
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Laube BL, Carson KA, Evans CM, Richardson VL, Sharpless G, Zeitlin PL, Mogayzel PJ. Changes in mucociliary clearance over time in children with cystic fibrosis. Pediatr Pulmonol. 2020 09; 55(9):2307-2314.
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Donaldson SH, Laube BL, Corcoran TE, Bhambhvani P, Zeman K, Ceppe A, Zeitlin PL, Mogayzel PJ, Boyle M, Locke LW, Myerburg MM, Pilewski JM, Flanagan B, Rowe SM, Bennett WD. Effect of ivacaftor on mucociliary clearance and clinical outcomes in cystic fibrosis patients with G551D-CFTR. JCI Insight. 2018 12 20; 3(24).
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Hancock LA, Hennessy CE, Solomon GM, Dobrinskikh E, Estrella A, Hara N, Hill DB, Kissner WJ, Markovetz MR, Grove Villalon DE, Voss ME, Tearney GJ, Carroll KS, Shi Y, Schwarz MI, Thelin WR, Rowe SM, Yang IV, Evans CM, Schwartz DA. Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice. Nat Commun. 2018 12 18; 9(1):5363.
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Benam KH, Vladar EK, Janssen WJ, Evans CM. Mucociliary Defense: Emerging Cellular, Molecular, and Animal Models. Ann Am Thorac Soc. 2018 11; 15(Suppl 3):S210-S215.
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Ni K, Gill A, Tseng V, Mikosz AM, Koike K, Beatman EL, Xu CY, Cao D, Gally F, Mould KJ, Serban KA, Schweitzer KS, March KL, Janssen WJ, Nozik-Grayck E, Garantziotis S, Petrache I. Rapid clearance of heavy chain-modified hyaluronan during resolving acute lung injury. Respir Res. 2018 05 31; 19(1):107.
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Evans CM, Fingerlin TE, Schwarz MI, Lynch D, Kurche J, Warg L, Yang IV, Schwartz DA. Idiopathic Pulmonary Fibrosis: A Genetic Disease That Involves Mucociliary Dysfunction of the Peripheral Airways. Physiol Rev. 2016 10; 96(4):1567-91.
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Janssen WJ, Stefanski AL, Bochner BS, Evans CM. Control of lung defence by mucins and macrophages: ancient defence mechanisms with modern functions. Eur Respir J. 2016 10; 48(4):1201-1214.
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