 Toll-Like Receptor 4
"Toll-Like Receptor 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pattern recognition receptor that interacts with LYMPHOCYTE ANTIGEN 96 and LIPOPOLYSACCHARIDES. It mediates cellular responses to GRAM-NEGATIVE BACTERIA.
| Descriptor ID |
D051197
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| MeSH Number(s) |
D12.776.543.750.705.910.500.400
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| Concept/Terms |
Toll-Like Receptor 4- Toll-Like Receptor 4
- Toll Like Receptor 4
- Toll-4 Receptor
- Toll 4 Receptor
- TLR4 Receptor
- Receptor, TLR4
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Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptor 4".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptor 4".
This graph shows the total number of publications written about "Toll-Like Receptor 4" by people in this website by year, and whether "Toll-Like Receptor 4" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 6 | 6 | | 2003 | 0 | 2 | 2 | | 2004 | 1 | 10 | 11 | | 2005 | 3 | 5 | 8 | | 2006 | 3 | 2 | 5 | | 2007 | 4 | 6 | 10 | | 2008 | 7 | 3 | 10 | | 2009 | 12 | 4 | 16 | | 2010 | 7 | 5 | 12 | | 2011 | 6 | 3 | 9 | | 2012 | 7 | 6 | 13 | | 2013 | 7 | 9 | 16 | | 2014 | 15 | 6 | 21 | | 2015 | 12 | 5 | 17 | | 2016 | 7 | 3 | 10 | | 2017 | 3 | 6 | 9 | | 2018 | 5 | 2 | 7 | | 2019 | 3 | 3 | 6 | | 2020 | 5 | 7 | 12 | | 2021 | 2 | 2 | 4 | | 2022 | 0 | 1 | 1 | | 2023 | 2 | 1 | 3 |
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Below are the most recent publications written about "Toll-Like Receptor 4" by people in Profiles.
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Ermisch AF, Bidne KL, Kurz SG, Bochantin KA, Wood JR. Ovarian inflammation mediated by Toll-like receptor 4 increased transcripts of maternal effect genes and decreased embryo development?. Biol Reprod. 2023 03 13; 108(3):423-436.
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Glaser K, Kern D, Speer CP, Schlegel N, Schwab M, Thome UH, H?rtel C, Wright CJ. Imbalanced Inflammatory Responses in Preterm and Term Cord Blood Monocytes and Expansion of the CD14+CD16+ Subset upon Toll-like Receptor Stimulation. Int J Mol Sci. 2023 Mar 03; 24(5).
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Langgartner D, Amoroso M, Kempter E, Kustermann M, Scheurer J, Lowry CA, Strau? G, Reber SO. Mycobacterium vaccae protects against glucocorticoid resistance resulting from combined physical and psychosocial trauma in mice. Brain Behav Immun. 2023 03; 109:221-234.
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Muscat SM, Deems NP, Butler MJ, Scaria EA, Bettes MN, Cleary SP, Bockbrader RH, Maier SF, Barrientos RM. Selective TLR4 Antagonism Prevents and Reverses Morphine-Induced Persistent Postoperative Cognitive Dysfunction, Dysregulation of Synaptic Elements, and Impaired BDNF Signaling in Aged Male Rats. J Neurosci. 2023 01 04; 43(1):155-172.
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Gergen AK, Jarrett MJ, Li A, Meng X, Pratap A, Fullerton DA, Weyant MJ. Toll-like Receptor 4 Mediates Reflux-Induced Inflammation in a Murine Reflux Model. Semin Thorac Cardiovasc Surg. 2022; 34(4):1324-1335.
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Jain S, Plenter R, Nydam T, Gill RG, Jani A. Deletion of TLR4 reduces apoptosis and improves histology in a murine kidney transplant model. Sci Rep. 2021 08 10; 11(1):16182.
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Abdelazeem KNM, Kalo MZ, Beer-Hammer S, Lang F. The gut microbiota metabolite urolithin A inhibits NF-?B activation in LPS stimulated BMDMs. Sci Rep. 2021 03 29; 11(1):7117.
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Kwilasz AJ, Green Fulgham SM, Duran-Malle JC, Schrama AEW, Mitten EH, Todd LS, Patel HP, Larson TA, Clements MA, Harris KM, Litwiler ST, Harvey LO, Maier SF, Chavez RA, Rice KC, Van Dam AM, Watkins LR. Toll-like receptor 2 and 4 antagonism for the treatment of experimental autoimmune encephalomyelitis (EAE)-related pain. Brain Behav Immun. 2021 03; 93:80-95.
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Gergen AK, Kohtz PD, Halpern AL, White AM, Meng X, Fullerton DA, Weyant MJ. Statins Inhibit Toll-Like Receptor 4-Mediated Growth of Human Esophageal Adenocarcinoma Cells. J Surg Res. 2021 04; 260:436-447.
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Muscat SM, Deems NP, D'Angelo H, Kitt MM, Grace PM, Andersen ND, Silverman SN, Rice KC, Watkins LR, Maier SF, Barrientos RM. Postoperative cognitive dysfunction is made persistent with morphine treatment in aged rats. Neurobiol Aging. 2021 02; 98:214-224.
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