 Toll-Like Receptor 4
"Toll-Like Receptor 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pattern recognition receptor that interacts with LYMPHOCYTE ANTIGEN 96 and LIPOPOLYSACCHARIDES. It mediates cellular responses to GRAM-NEGATIVE BACTERIA.
| Descriptor ID |
D051197
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| MeSH Number(s) |
D12.776.543.750.705.910.500.400
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| Concept/Terms |
Toll-Like Receptor 4- Toll-Like Receptor 4
- Toll Like Receptor 4
- Toll-4 Receptor
- Toll 4 Receptor
- TLR4 Receptor
- Receptor, TLR4
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Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptor 4".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptor 4".
This graph shows the total number of publications written about "Toll-Like Receptor 4" by people in this website by year, and whether "Toll-Like Receptor 4" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2001 | 0 | 7 | 7 | | 2002 | 0 | 10 | 10 | | 2003 | 0 | 2 | 2 | | 2004 | 1 | 10 | 11 | | 2005 | 4 | 5 | 9 | | 2006 | 3 | 3 | 6 | | 2007 | 4 | 7 | 11 | | 2008 | 8 | 3 | 11 | | 2009 | 14 | 5 | 19 | | 2010 | 7 | 3 | 10 | | 2011 | 6 | 3 | 9 | | 2012 | 8 | 8 | 16 | | 2013 | 7 | 9 | 16 | | 2014 | 13 | 6 | 19 | | 2015 | 11 | 4 | 15 | | 2016 | 6 | 3 | 9 | | 2017 | 3 | 6 | 9 | | 2018 | 4 | 0 | 4 |
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Below are the most recent publications written about "Toll-Like Receptor 4" by people in Profiles.
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Karoly HC, Ellingson JM, Hutchison KE. Interactions between TLR4 methylation and alcohol consumption on subjective responses to an alcohol infusion. Alcohol Alcohol. 2018 Nov 01; 53(6):650-658.
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Kohtz PD, Halpern AL, Eldeiry MA, Hazel K, Kalatardi S, Ao L, Meng X, Reece TB, Fullerton DA, Weyant MJ. Toll-Like Receptor-4 Is a Mediator of Proliferation in Esophageal Adenocarcinoma. Ann Thorac Surg. 2019 01; 107(1):233-241.
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Hirai K, Furusho H, Kawashima N, Xu S, de Beer MC, Battaglino R, Van Dyke T, Stashenko P, Sasaki H. Serum Amyloid A Contributes to Chronic Apical Periodontitis via TLR2 and TLR4. J Dent Res. 2019 01; 98(1):117-125.
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Venardos N, Deng XS, Yao Q, Weyant MJ, Reece TB, Meng X, Fullerton DA. Simvastatin reduces the TLR4-induced inflammatory response in human aortic valve interstitial cells. J Surg Res. 2018 10; 230:101-109.
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Zhang X, Cui F, Chen H, Zhang T, Yang K, Wang Y, Jiang Z, Rice KC, Watkins LR, Hutchinson MR, Li Y, Peng Y, Wang X. Dissecting the Innate Immune Recognition of Opioid Inactive Isomer (+)-Naltrexone Derived Toll-like Receptor 4 (TLR4) Antagonists. J Chem Inf Model. 2018 04 23; 58(4):816-825.
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Saikia P, Roychowdhury S, Bellos D, Pollard KA, McMullen MR, McCullough RL, McCullough AJ, Gholam P, de la Motte C, Nagy LE. Hyaluronic acid 35 normalizes TLR4 signaling in Kupffer cells from ethanol-fed rats via regulation of microRNA291b and its target Tollip. Sci Rep. 2017 Nov 15; 7(1):15671.
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Tiwari A, Singh P, Jaitley P, Sharma S, Prakash A, Mandil R, Choudhury S, Gangwar NK, Garg SK. Eucalyptus robusta leaves methanolic extract suppresses inflammatory mediators by specifically targeting TLR4/TLR9, MPO, COX2, iNOS and inflammatory cytokines in experimentally-induced endometritis in rats. J Ethnopharmacol. 2018 Mar 01; 213:149-158.
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Karoly HC, Thayer RE, Hagerty SL, Hutchison KE. TLR4 Methylation Moderates the Relationship Between Alcohol Use Severity and Gray Matter Loss. J Stud Alcohol Drugs. 2017 09; 78(5):696-705.
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Grace PM, Strand KA, Galer EL, Rice KC, Maier SF, Watkins LR. Protraction of neuropathic pain by morphine is mediated by spinal damage associated molecular patterns (DAMPs) in male rats. Brain Behav Immun. 2018 08; 72:45-50.
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Brown KT, Levis SC, O'Neill CE, Northcutt AL, Fabisiak TJ, Watkins LR, Bachtell RK. Innate immune signaling in the ventral tegmental area contributes to drug-primed reinstatement of cocaine seeking. Brain Behav Immun. 2018 Jan; 67:130-138.
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