 Chemical and Drug Induced Liver Injury
"Chemical and Drug Induced Liver Injury" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Descriptor ID |
D056486
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| MeSH Number(s) |
C06.552.195 C25.100.562 C25.723.260
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| Concept/Terms |
Chemically-Induced Liver Toxicity- Chemically-Induced Liver Toxicity
- Chemically Induced Liver Toxicity
- Chemically-Induced Liver Toxicities
- Liver Toxicities, Chemically-Induced
- Liver Toxicity, Chemically-Induced
- Toxicities, Chemically-Induced Liver
- Toxicity, Chemically-Induced Liver
Drug-Induced Acute Liver Injury- Drug-Induced Acute Liver Injury
- Drug Induced Acute Liver Injury
- Liver Injury, Drug-Induced, Acute
- Acute Liver Injury, Drug-Induced
- Acute Liver Injury, Drug Induced
Hepatitis, Toxic- Hepatitis, Toxic
- Toxic Hepatitis
- Hepatitides, Toxic
- Toxic Hepatitides
Drug-Induced Liver Disease- Drug-Induced Liver Disease
- Disease, Drug-Induced Liver
- Diseases, Drug-Induced Liver
- Drug Induced Liver Disease
- Drug-Induced Liver Diseases
- Liver Disease, Drug-Induced
- Liver Diseases, Drug-Induced
- Drug-Induced Liver Injury
- Drug Induced Liver Injury
- Drug-Induced Liver Injuries
- Injuries, Drug-Induced Liver
- Injury, Drug-Induced Liver
- Liver Injuries, Drug-Induced
- Liver Injury, Drug-Induced
- Liver Injury, Drug Induced
Hepatitis, Drug-Induced- Hepatitis, Drug-Induced
- Drug-Induced Hepatitides
- Drug-Induced Hepatitis
- Hepatitides, Drug-Induced
- Hepatitis, Drug Induced
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Below are MeSH descriptors whose meaning is more general than "Chemical and Drug Induced Liver Injury".
Below are MeSH descriptors whose meaning is more specific than "Chemical and Drug Induced Liver Injury".
This graph shows the total number of publications written about "Chemical and Drug Induced Liver Injury" by people in this website by year, and whether "Chemical and Drug Induced Liver Injury" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 0 | 1 | | 1995 | 1 | 0 | 1 | | 1996 | 1 | 2 | 3 | | 1998 | 2 | 0 | 2 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 3 | 3 | 6 | | 2004 | 3 | 0 | 3 | | 2005 | 1 | 1 | 2 | | 2006 | 1 | 1 | 2 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 2 | 3 | | 2010 | 3 | 0 | 3 | | 2011 | 3 | 2 | 5 | | 2012 | 3 | 0 | 3 | | 2013 | 2 | 0 | 2 | | 2014 | 5 | 1 | 6 | | 2016 | 1 | 2 | 3 | | 2018 | 4 | 1 | 5 | | 2020 | 3 | 1 | 4 | | 2021 | 6 | 0 | 6 | | 2022 | 2 | 0 | 2 |
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Below are the most recent publications written about "Chemical and Drug Induced Liver Injury" by people in Profiles.
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Sherlock LG, Balasubramaniyan D, Zheng L, Grayck M, McCarthy WC, De Dios RC, Zarate MA, Orlicky DJ, De Dios R, Wright CJ. APAP-Induced I?Bß/NF?B Signaling Drives Hepatic Il6 Expression and Associated Sinusoidal Dilation. Toxicol Sci. 2022 01 24; 185(2):158-169.
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Akakpo JY, Ramachandran A, Curry SC, Rumack BH, Jaeschke H. Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose. Arch Toxicol. 2022 02; 96(2):453-465.
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Mudan A, Lebin JA, Wu AHB, Livshits Z. Serum iron concentrations in non-iron induced acute liver injury. Clin Chim Acta. 2022 Jan 15; 525:12-14.
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Mehrpour O, Saeedi F, Hoyte C. Decision tree outcome prediction of acute acetaminophen exposure in the United States: A study of 30,000 cases from the National Poison Data System. Basic Clin Pharmacol Toxicol. 2022 Jan; 130(1):191-199.
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Link SL, Rampon G, Osmon S, Scalzo AJ, Rumack BH. Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series. Clin Toxicol (Phila). 2022 Apr; 60(4):472-477.
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Lebin JA, Mudan A, Zhang Y, Wu AHB, Smollin CG. Circulating miR-122 in patients with non-toxic acute acetaminophen ingestions. Clin Toxicol (Phila). 2022 04; 60(4):527-529.
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Akakpo JY, Jaeschke MW, Ramachandran A, Curry SC, Rumack BH, Jaeschke H. Delayed administration of N-acetylcysteine blunts recovery after an acetaminophen overdose unlike 4-methylpyrazole. Arch Toxicol. 2021 10; 95(10):3377-3391.
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Sonn BJ, Heard KJ, Heard SM, D'Alessandro A, Reynolds KM, Dart RC, Rumack BH, Monte AA. Metabolomic markers predictive of hepatic adaptation to therapeutic dosing of acetaminophen. Clin Toxicol (Phila). 2022 Feb; 60(2):221-230.
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Akakpo JY, Ramachandran A, Orhan H, Curry SC, Rumack BH, Jaeschke H. 4-methylpyrazole protects against acetaminophen-induced acute kidney injury. Toxicol Appl Pharmacol. 2020 12 15; 409:115317.
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Monte AA, Sonn B, Saben J, Rumack BH, Reynolds KM, Dart RC, Heard KJ. The Genomics of Elevated ALT and Adducts in Therapeutic Acetaminophen Treatment: a Pilot Study. J Med Toxicol. 2021 04; 17(2):160-167.
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