 Chemical and Drug Induced Liver Injury
"Chemical and Drug Induced Liver Injury" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Descriptor ID |
D056486
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| MeSH Number(s) |
C06.552.195 C25.100.562 C25.723.260
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| Concept/Terms |
Chemically-Induced Liver Toxicity- Chemically-Induced Liver Toxicity
- Chemically Induced Liver Toxicity
- Chemically-Induced Liver Toxicities
- Liver Toxicities, Chemically-Induced
- Liver Toxicity, Chemically-Induced
- Toxicities, Chemically-Induced Liver
- Toxicity, Chemically-Induced Liver
Drug-Induced Acute Liver Injury- Drug-Induced Acute Liver Injury
- Drug Induced Acute Liver Injury
- Liver Injury, Drug-Induced, Acute
- Acute Liver Injury, Drug-Induced
- Acute Liver Injury, Drug Induced
Hepatitis, Toxic- Hepatitis, Toxic
- Toxic Hepatitis
- Hepatitides, Toxic
- Toxic Hepatitides
Drug-Induced Liver Disease- Drug-Induced Liver Disease
- Disease, Drug-Induced Liver
- Diseases, Drug-Induced Liver
- Drug Induced Liver Disease
- Drug-Induced Liver Diseases
- Liver Disease, Drug-Induced
- Liver Diseases, Drug-Induced
- Drug-Induced Liver Injury
- Drug Induced Liver Injury
- Drug-Induced Liver Injuries
- Injuries, Drug-Induced Liver
- Injury, Drug-Induced Liver
- Liver Injuries, Drug-Induced
- Liver Injury, Drug-Induced
- Liver Injury, Drug Induced
Hepatitis, Drug-Induced- Hepatitis, Drug-Induced
- Drug-Induced Hepatitides
- Drug-Induced Hepatitis
- Hepatitides, Drug-Induced
- Hepatitis, Drug Induced
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Below are MeSH descriptors whose meaning is more general than "Chemical and Drug Induced Liver Injury".
Below are MeSH descriptors whose meaning is more specific than "Chemical and Drug Induced Liver Injury".
This graph shows the total number of publications written about "Chemical and Drug Induced Liver Injury" by people in this website by year, and whether "Chemical and Drug Induced Liver Injury" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 0 | 1 | | 1995 | 2 | 0 | 2 | | 1996 | 1 | 1 | 2 | | 1998 | 2 | 0 | 2 | | 2000 | 1 | 1 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 1 | 2 | | 2003 | 5 | 3 | 8 | | 2004 | 3 | 0 | 3 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 1 | 2 | | 2007 | 3 | 1 | 4 | | 2008 | 1 | 2 | 3 | | 2009 | 2 | 1 | 3 | | 2010 | 5 | 0 | 5 | | 2011 | 2 | 2 | 4 | | 2012 | 5 | 1 | 6 | | 2013 | 2 | 1 | 3 | | 2014 | 5 | 1 | 6 | | 2015 | 0 | 1 | 1 | | 2016 | 3 | 2 | 5 | | 2017 | 1 | 0 | 1 | | 2018 | 4 | 2 | 6 |
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Below are the most recent publications written about "Chemical and Drug Induced Liver Injury" by people in Profiles.
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Neil D, Clark RV, Magee M, Billiard J, Chan A, Xue Z, Russell A. GSK2881078, a SARM, Produces Dose-Dependent Increases in Lean Mass in Healthy Older Men and Women. J Clin Endocrinol Metab. 2018 09 01; 103(9):3215-3224.
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Akakpo JY, Ramachandran A, Kandel SE, Ni HM, Kumer SC, Rumack BH, Jaeschke H. 4-Methylpyrazole protects against acetaminophen hepatotoxicity in mice and in primary human hepatocytes. Hum Exp Toxicol. 2018 Dec; 37(12):1310-1322.
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McGreal SR, Bhushan B, Walesky C, McGill MR, Lebofsky M, Kandel SE, Winefield RD, Jaeschke H, Zachara NE, Zhang Z, Tan EP, Slawson C, Apte U. Modulation of O-GlcNAc Levels in the Liver Impacts Acetaminophen-Induced Liver Injury by Affecting Protein Adduct Formation and Glutathione Synthesis. Toxicol Sci. 2018 04 01; 162(2):599-610.
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Li H, Byers HM, Diaz-Kuan A, Vos MB, Hall PL, Tortorelli S, Singh R, Wallenstein MB, Allain M, Dimmock DP, Farrell RM, McCandless S, Gambello MJ. Acute liver failure in neonates with undiagnosed hereditary fructose intolerance due to exposure from widely available infant formulas. Mol Genet Metab. 2018 04; 123(4):428-432.
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Wood PR, Caplan L. Drug-Induced Gastrointestinal and Hepatic Disease Associated with Biologics and Nonbiologic Disease-Modifying Antirheumatic Drugs. Rheum Dis Clin North Am. 2018 02; 44(1):29-43.
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Brandehoff NP, Baker KA, Bonney CF, Ng PC, Schimmel J, Hoyte CO. Articles You May Have Missed. J Med Toxicol. 2018 06; 14(2):156-159.
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Heard K, Anderson V, Dart RC, Kile D, Lavonas EJ, Green JL. Serum Acetaminophen Protein Adduct Concentrations in Pediatric Emergency Department Patients. J Pediatr Gastroenterol Nutr. 2017 04; 64(4):533-535.
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Madden JR, Evans A, Hemenway M, Stark E, Kissell E, Polito A, Batson D, Stark M, Dhall G, Garvin JH, Foreman NK, Vibhakar R. Vincristine and Vinblastine: Is checking bilirubin mandatory in children with Brain Tumors? Pediatr Blood Cancer. 2017 06; 64(6).
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Arya V, Kiser JJ. Role of Transporters in Drug Development. J Clin Pharmacol. 2016 07; 56 Suppl 7:S7-S10.
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Qiu X, Zhang Y, Liu T, Shen H, Xiao Y, Bourner MJ, Pratt JR, Thompson DC, Marathe P, Humphreys WG, Lai Y. Disruption of BSEP Function in HepaRG Cells Alters Bile Acid Disposition and Is a Susceptive Factor to Drug-Induced Cholestatic Injury. Mol Pharm. 2016 Apr 04; 13(4):1206-16.
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