 Methacholine Chloride
"Methacholine Chloride" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116)
| Descriptor ID |
D016210
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| MeSH Number(s) |
D02.092.877.883.555.500 D02.675.276.534.500
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| Concept/Terms |
Methacholine Chloride- Methacholine Chloride
- Chloride, Methacholine
- Acetyl-2-methylcholine Chloride
- Acetyl 2 methylcholine Chloride
- Mecholine
- 2-(Acetyloxy)-N,N,N-trimethyl-1-propanaminium Chloride
- Acetyl-beta-methacholine Chloride
- Acetyl beta methacholine Chloride
Provocholine- Provocholine
- Roche Brand of Methacholine Chloride
- Methapharma Brand of Methacholine Chloride
Provokit- Provokit
- Lindopharm Brand of Methacholine Chloride
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Below are MeSH descriptors whose meaning is more general than "Methacholine Chloride".
Below are MeSH descriptors whose meaning is more specific than "Methacholine Chloride".
This graph shows the total number of publications written about "Methacholine Chloride" by people in this website by year, and whether "Methacholine Chloride" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 0 | 1 | 1 | | 1991 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 0 | 3 | 3 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 3 | 3 | | 2002 | 0 | 3 | 3 | | 2003 | 1 | 4 | 5 | | 2004 | 0 | 4 | 4 | | 2005 | 0 | 3 | 3 | | 2006 | 0 | 6 | 6 | | 2007 | 0 | 3 | 3 | | 2008 | 0 | 3 | 3 | | 2009 | 0 | 2 | 2 | | 2010 | 0 | 3 | 3 | | 2011 | 0 | 2 | 2 | | 2012 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 3 | 3 | | 2016 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Methacholine Chloride" by people in Profiles.
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Pearson J, Ganio MS, Schlader ZJ, Lucas RA, Gagnon D, Rivas E, Davis SL, Kowalske KJ, Crandall CG. Post Junctional Sudomotor and Cutaneous Vascular Responses in Noninjured Skin Following Heat Acclimation in Burn Survivors. J Burn Care Res. 2017 Jan/Feb; 38(1):e284-e292.
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Dylag AM, Mayer CA, Raffay TM, Martin RJ, Jafri A, MacFarlane PM. Long-term effects of recurrent intermittent hypoxia and hyperoxia on respiratory system mechanics in neonatal mice. Pediatr Res. 2017 Apr; 81(4):565-571.
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Dixon AE, Subramanian M, DeSarno M, Black K, Lane L, Holguin F. A pilot randomized controlled trial of pioglitazone for the treatment of poorly controlled asthma in obesity. Respir Res. 2015 Nov 26; 16:143.
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Faksh A, Britt RD, Vogel ER, Kuipers I, Thompson MA, Sieck GC, Pabelick CM, Martin RJ, Prakash YS. Effects of antenatal lipopolysaccharide and postnatal hyperoxia on airway reactivity and remodeling in a neonatal mouse model. Pediatr Res. 2016 Mar; 79(3):391-400.
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Evans CM, Raclawska DS, Ttofali F, Liptzin DR, Fletcher AA, Harper DN, McGing MA, McElwee MM, Williams OW, Sanchez E, Roy MG, Kindrachuk KN, Wynn TA, Eltzschig HK, Blackburn MR, Tuvim MJ, Janssen WJ, Schwartz DA, Dickey BF. The polymeric mucin Muc5ac is required for allergic airway hyperreactivity. Nat Commun. 2015 Feb 17; 6:6281.
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Wang H, Jafri A, Martin RJ, Nnanabu J, Farver C, Prakash YS, MacFarlane PM. Severity of neonatal hyperoxia determines structural and functional changes in developing mouse airway. Am J Physiol Lung Cell Mol Physiol. 2014 Aug 15; 307(4):L295-301.
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Hanifi A, Goplen N, Matin M, Salters RE, Alam R. A linear parametric approach for analysis of mouse respiratory impedance. IEEE Trans Biomed Circuits Syst. 2012 Jun; 6(3):287-94.
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Shin YS, Takeda K, Shiraishi Y, Jia Y, Wang M, Jackson L, Wright AD, Carter L, Robinson J, Hicken E, Gelfand EW. Inhibition of Pim1 kinase activation attenuates allergen-induced airway hyperresponsiveness and inflammation. Am J Respir Cell Mol Biol. 2012 Apr; 46(4):488-97.
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Kelada SN, Wilson MS, Tavarez U, Kubalanza K, Borate B, Whitehead GS, Maruoka S, Roy MG, Olive M, Carpenter DE, Brass DM, Wynn TA, Cook DN, Evans CM, Schwartz DA, Collins FS. Strain-dependent genomic factors affect allergen-induced airway hyperresponsiveness in mice. Am J Respir Cell Mol Biol. 2011 Oct; 45(4):817-24.
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Pastva AM, Walker JK, Maddox LA, Mukherjee S, Giamberardino C, Hsia B, Potts E, Zhu H, Degan S, Sunday ME, Lawson BL, Korfhagen TR, Schwartz DA, Eu JP, Foster WM, McMahon TJ, Que L, Wright JR. Nitric oxide mediates relative airway hyporesponsiveness to lipopolysaccharide in surfactant protein A-deficient mice. Am J Respir Cell Mol Biol. 2011 Feb; 44(2):175-84.
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