 West Nile virus
"West Nile virus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A species of FLAVIVIRUS, one of the Japanese encephalitis virus group (ENCEPHALITIS VIRUSES, JAPANESE). It can infect birds and mammals. In humans, it is seen most frequently in Africa, Asia, and Europe presenting as a silent infection or undifferentiated fever (WEST NILE FEVER). The virus appeared in North America for the first time in 1999. It is transmitted mainly by CULEX spp mosquitoes which feed primarily on birds, but it can also be carried by the Asian Tiger mosquito, AEDES albopictus, which feeds mainly on mammals.
| Descriptor ID |
D014902
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| MeSH Number(s) |
B04.820.230.475.950 B04.820.250.350.300.950
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "West Nile virus".
Below are MeSH descriptors whose meaning is more specific than "West Nile virus".
This graph shows the total number of publications written about "West Nile virus" by people in this website by year, and whether "West Nile virus" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 2 | 0 | 2 | | 2005 | 3 | 0 | 3 | | 2006 | 3 | 1 | 4 | | 2007 | 3 | 0 | 3 | | 2008 | 3 | 0 | 3 | | 2009 | 1 | 0 | 1 | | 2010 | 2 | 1 | 3 | | 2012 | 5 | 0 | 5 | | 2013 | 1 | 0 | 1 | | 2014 | 6 | 0 | 6 | | 2015 | 2 | 0 | 2 | | 2016 | 2 | 0 | 2 | | 2017 | 3 | 0 | 3 | | 2018 | 1 | 1 | 2 | | 2019 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "West Nile virus" by people in Profiles.
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Stonedahl S, Leser JS, Clarke P, Potter H, Boyd TD, Tyler KL. Treatment with Granulocyte-Macrophage Colony-Stimulating Factor Reduces Viral Titers in the Brains of West Nile Virus-Infected Mice and Improves Survival. J Virol. 2023 Mar 30; 97(3):e0180522.
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Stonedahl S, Leser JS, Clarke P, Tyler KL. Depletion of Microglia in an Ex Vivo Brain Slice Culture Model of West Nile Virus Infection Leads to Increased Viral Titers and Cell Death. Microbiol Spectr. 2022 04 27; 10(2):e0068522.
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Clarke P, Leser JS, Tyler KL. Intrinsic Innate Immune Responses Control Viral Growth and Protect against Neuronal Death in an Ex Vivo Model of West Nile Virus-Induced Central Nervous System Disease. J Virol. 2021 08 25; 95(18):e0083521.
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Gnann JW, Agrawal A, Hart J, Buitrago M, Carson P, Hanfelt-Goade D, Tyler K, Spotkov J, Freifeld A, Moore T, Reyno J, Masur H, Jester P, Dale I, Li Y, Aban I, Lakeman FD, Whitley RJ. Lack of Efficacy of High-Titered Immunoglobulin in Patients with West Nile Virus Central Nervous System Disease. Emerg Infect Dis. 2019 11; 25(11):2064-2073.
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Lesteberg KE, Beckham JD. Immunology of West Nile Virus Infection and the Role of Alpha-Synuclein as a Viral Restriction Factor. Viral Immunol. 2019 Jan/Feb; 32(1):38-47.
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Seitz S, Clarke P, Tyler KL. Pharmacologic Depletion of Microglia Increases Viral Load in the Brain and Enhances Mortality in Murine Models of Flavivirus-Induced Encephalitis. J Virol. 2018 08 15; 92(16).
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Quick ED, Seitz S, Clarke P, Tyler KL. Minocycline Has Anti-inflammatory Effects and Reduces Cytotoxicity in an Ex Vivo Spinal Cord Slice Culture Model of West Nile Virus Infection. J Virol. 2017 11 15; 91(22).
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Murray KO, Kolodziej S, Ronca SE, Gorchakov R, Navarro P, Nolan MS, Podoll A, Finkel K, Mandayam S. Visualization of West Nile Virus in Urine Sediment using Electron Microscopy and Immunogold up to Nine Years Postinfection. Am J Trop Med Hyg. 2017 Dec; 97(6):1913-1919.
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Shives KD, Tyler KL, Beckham JD. Molecular mechanisms of neuroinflammation and injury during acute viral encephalitis. J Neuroimmunol. 2017 07 15; 308:102-111.
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Paull SH, Horton DE, Ashfaq M, Rastogi D, Kramer LD, Diffenbaugh NS, Kilpatrick AM. Drought and immunity determine the intensity of West Nile virus epidemics and climate change impacts. Proc Biol Sci. 2017 02 08; 284(1848).
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