Lipoprotein Lipase
"Lipoprotein Lipase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme hydrolyzes triacylglycerols in chylomicrons, very-low-density lipoproteins, low-density lipoproteins, and diacylglycerols. It occurs on capillary endothelial surfaces, especially in mammary, muscle, and adipose tissue. Genetic deficiency of the enzyme causes familial hyperlipoproteinemia Type I. (Dorland, 27th ed) EC 3.1.1.34.
Descriptor ID |
D008071
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MeSH Number(s) |
D08.811.277.352.100.430
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Concept/Terms |
Lipoprotein Lipase- Lipoprotein Lipase
- Lipase, Lipoprotein
- Diglyceride Lipase
- Lipase, Diglyceride
- Heparin-Clearing Factor
- Factor, Heparin-Clearing
- Heparin Clearing Factor
- Post-Heparin Lipase
- Lipase, Post-Heparin
- Post Heparin Lipase
- Postheparin Lipase
- Lipase, Postheparin
- Postheparin Lipoprotein Lipase
- Lipase, Postheparin Lipoprotein
- Lipoprotein Lipase, Postheparin
- Diacylglycerol Lipase
- Lipase, Diacylglycerol
- Lipemia-Clearing Factor
- Factor, Lipemia-Clearing
- Lipemia Clearing Factor
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Below are MeSH descriptors whose meaning is more general than "Lipoprotein Lipase".
Below are MeSH descriptors whose meaning is more specific than "Lipoprotein Lipase".
This graph shows the total number of publications written about "Lipoprotein Lipase" by people in this website by year, and whether "Lipoprotein Lipase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1991 | 4 | 0 | 4 | 1992 | 2 | 2 | 4 | 1993 | 7 | 1 | 8 | 1994 | 3 | 0 | 3 | 1995 | 5 | 2 | 7 | 1996 | 2 | 2 | 4 | 1997 | 3 | 2 | 5 | 1998 | 3 | 0 | 3 | 1999 | 4 | 0 | 4 | 2000 | 5 | 1 | 6 | 2001 | 5 | 0 | 5 | 2002 | 4 | 1 | 5 | 2003 | 2 | 0 | 2 | 2004 | 2 | 1 | 3 | 2006 | 7 | 1 | 8 | 2007 | 1 | 0 | 1 | 2008 | 3 | 0 | 3 | 2009 | 2 | 0 | 2 | 2010 | 2 | 1 | 3 | 2011 | 1 | 0 | 1 | 2012 | 4 | 0 | 4 | 2013 | 1 | 2 | 3 | 2014 | 1 | 1 | 2 | 2015 | 2 | 1 | 3 | 2016 | 1 | 1 | 2 | 2017 | 2 | 2 | 4 | 2018 | 2 | 1 | 3 | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lipoprotein Lipase" by people in Profiles.
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Chait A, Eckel RH. The Chylomicronemia Syndrome Is Most Often Multifactorial: A Narrative Review of Causes and Treatment. Ann Intern Med. 2019 05 07; 170(9):626-634.
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Falko JM. Familial Chylomicronemia Syndrome: A Clinical Guide For Endocrinologists. Endocr Pract. 2018 08; 24(8):756-763.
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Heerwagen MJR, Gumina DL, Hernandez TL, Van Pelt RE, Kramer AW, Janssen RC, Jensen DR, Powell TL, Friedman JE, Winn VD, Barbour LA. Placental lipoprotein lipase activity is positively associated with newborn adiposity. Placenta. 2018 04; 64:53-60.
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Gadek KE, Wang H, Hall MN, Sungello M, Libby A, MacLaskey D, Eckel RH, Olwin BB. Striated muscle gene therapy for the treatment of lipoprotein lipase deficiency. PLoS One. 2018; 13(1):e0190963.
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Gao Y, Vidal-Itriago A, Kalsbeek MJ, Layritz C, García-Cáceres C, Tom RZ, Eichmann TO, Vaz FM, Houtkooper RH, van der Wel N, Verhoeven AJ, Yan J, Kalsbeek A, Eckel RH, Hofmann SM, Yi CX. Lipoprotein Lipase Maintains Microglial Innate Immunity in Obesity. Cell Rep. 2017 Sep 26; 20(13):3034-3042.
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Gao Y, Layritz C, Legutko B, Eichmann TO, Laperrousaz E, Moullé VS, Cruciani-Guglielmacci C, Magnan C, Luquet S, Woods SC, Eckel RH, Yi CX, Garcia-Caceres C, Tschöp MH. Disruption of Lipid Uptake in Astroglia Exacerbates Diet-Induced Obesity. Diabetes. 2017 10; 66(10):2555-2563.
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Laperrousaz E, Moullé VS, Denis RG, Kassis N, Berland C, Colsch B, Fioramonti X, Philippe E, Lacombe A, Vanacker C, Butin N, Bruce KD, Wang H, Wang Y, Gao Y, Garcia-Caceres C, Prévot V, Tschöp MH, Eckel RH, Le Stunff H, Luquet S, Magnan C, Cruciani-Guglielmacci C. Lipoprotein lipase in hypothalamus is a key regulator of body weight gain and glucose homeostasis in mice. Diabetologia. 2017 07; 60(7):1314-1324.
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Yu T, Sungelo MJ, Goldberg IJ, Wang H, Eckel RH. Streptozotocin-Treated High Fat Fed Mice: A New Type 2 Diabetes Model Used to Study Canagliflozin-Induced Alterations in Lipids and Lipoproteins. Horm Metab Res. 2017 May; 49(5):400-406.
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Capitena CE, Wagoner HJ, Ruzas CM, Bennett TD, Baker PR, Jung JL, Weisfeld-Adams JD. Rapid resolution of infantile lipemia retinalis following exchange transfusion. J Inherit Metab Dis. 2016 11; 39(6):889-890.
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Wang H, Taussig MD, DiPatrizio NV, Bruce K, Piomelli D, Eckel RH. Obesity development in neuron-specific lipoprotein lipase deficient mice is not responsive to increased dietary fat content or change in fat composition. Metabolism. 2016 07; 65(7):987-97.
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