Protoporphyrins
"Protoporphyrins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Porphyrins with four methyl, two vinyl, and two propionic acid side chains attached to the pyrrole rings. Protoporphyrin IX occurs in hemoglobin, myoglobin, and most of the cytochromes.
Descriptor ID |
D011524
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MeSH Number(s) |
D03.383.129.578.840.500.725 D03.633.400.909.500.725 D04.345.783.500.725 D23.767.727.725
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Protoporphyrins".
Below are MeSH descriptors whose meaning is more specific than "Protoporphyrins".
This graph shows the total number of publications written about "Protoporphyrins" by people in this website by year, and whether "Protoporphyrins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 | 2004 | 0 | 1 | 1 | 2006 | 1 | 0 | 1 | 2007 | 0 | 1 | 1 | 2009 | 1 | 1 | 2 | 2011 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2014 | 0 | 1 | 1 | 2015 | 1 | 0 | 1 | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protoporphyrins" by people in Profiles.
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Lamberti MJ, Mentucci FM, Roselli E, Araya P, Rivarola VA, Rumie Vittar NB, Maccioni M. Photodynamic Modulation of Type 1 Interferon Pathway on Melanoma Cells Promotes Dendritic Cell Activation. Front Immunol. 2019; 10:2614.
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Wang S, Hannafon BN, Lind SE, Ding WQ. Zinc Protoporphyrin Suppresses ?-Catenin Protein Expression in Human Cancer Cells: The Potential Involvement of Lysosome-Mediated Degradation. PLoS One. 2015; 10(5):e0127413.
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Pieracci FM, Stovall RT, Jaouen B, Rodil M, Cappa A, Burlew CC, Holena DN, Maier R, Berry S, Jurkovich J, Moore EE. A multicenter, randomized clinical trial of IV iron supplementation for anemia of traumatic critical illness*. Crit Care Med. 2014 Sep; 42(9):2048-57.
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Wang S, Avery JE, Hannafon BN, Lind SE, Ding WQ. Zinc protoporphyrin suppresses cancer cell viability through a heme oxygenase-1-independent mechanism: the involvement of the Wnt/?-catenin signaling pathway. Biochem Pharmacol. 2013 Jun 01; 85(11):1611-8.
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Majtan T, Freeman KM, Smith AT, Burstyn JN, Kraus JP. Purification and characterization of cystathionine ?-synthase bearing a cobalt protoporphyrin. Arch Biochem Biophys. 2011 Apr 01; 508(1):25-30.
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Majtan T, Frerman FE, Kraus JP. Effect of cobalt on Escherichia coli metabolism and metalloporphyrin formation. Biometals. 2011 Apr; 24(2):335-47.
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La P, Fernando AP, Wang Z, Salahudeen A, Yang G, Lin Q, Wright CJ, Dennery PA. Zinc protoporphyrin regulates cyclin D1 expression independent of heme oxygenase inhibition. J Biol Chem. 2009 Dec 25; 284(52):36302-36311.
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Roach JP, Moore EE, Partrick DA, Damle SS, Silliman CC, McIntyre RC, Banerjee A. Heme oxygenase-1 induction in macrophages by a hemoglobin-based oxygen carrier reduces endotoxin-stimulated cytokine secretion. Shock. 2009 Mar; 31(3):251-7.
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Rangarajan S, D'Souza GA. Restless legs syndrome in Indian patients having iron deficiency anemia in a tertiary care hospital. Sleep Med. 2007 Apr; 8(3):247-51.
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Cho BM, Carlsson CF, Jimenez R. Photon echo spectroscopy of porphyrins and heme proteins: effects of quasidegenerate electronic structure on the peak shift decay. J Chem Phys. 2006 Apr 14; 124(14):144905.
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