 Insulin-Like Growth Factor I
"Insulin-Like Growth Factor I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.
| Descriptor ID |
D007334
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| MeSH Number(s) |
D12.644.276.937.400 D12.776.124.862.400 D12.776.467.937.400 D23.529.937.400
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| Concept/Terms |
Insulin-Like Growth Factor I- Insulin-Like Growth Factor I
- Insulin-Like Somatomedin Peptide I
- Insulin Like Somatomedin Peptide I
- Somatomedin C
- IGF-I-SmC
- IGF-1
- IGF-I
- Insulin Like Growth Factor I
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Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor I".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor I".
This graph shows the total number of publications written about "Insulin-Like Growth Factor I" by people in this website by year, and whether "Insulin-Like Growth Factor I" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 1 | 2 | | 1992 | 1 | 2 | 3 | | 1993 | 2 | 0 | 2 | | 1994 | 4 | 1 | 5 | | 1995 | 0 | 2 | 2 | | 1996 | 2 | 0 | 2 | | 1997 | 4 | 5 | 9 | | 1998 | 6 | 4 | 10 | | 1999 | 3 | 1 | 4 | | 2000 | 1 | 5 | 6 | | 2001 | 2 | 2 | 4 | | 2002 | 2 | 2 | 4 | | 2003 | 4 | 1 | 5 | | 2004 | 5 | 2 | 7 | | 2005 | 4 | 4 | 8 | | 2006 | 5 | 10 | 15 | | 2007 | 2 | 2 | 4 | | 2008 | 4 | 3 | 7 | | 2009 | 6 | 4 | 10 | | 2010 | 4 | 4 | 8 | | 2011 | 2 | 2 | 4 | | 2012 | 2 | 5 | 7 | | 2013 | 2 | 4 | 6 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 4 | 5 | | 2016 | 1 | 0 | 1 | | 2017 | 6 | 2 | 8 | | 2018 | 2 | 4 | 6 | | 2019 | 0 | 3 | 3 | | 2020 | 3 | 2 | 5 | | 2021 | 4 | 2 | 6 |
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Below are the most recent publications written about "Insulin-Like Growth Factor I" by people in Profiles.
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Tanner AR, Lynch CS, Kennedy VC, Ali A, Winger QA, Rozance PJ, Anthony RV. CSH RNA Interference Reduces Global Nutrient Uptake and Umbilical Blood Flow Resulting in Intrauterine Growth Restriction. Int J Mol Sci. 2021 Jul 29; 22(15).
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Dumolt JH, Powell TL, Jansson T. Placental Function and the Development of Fetal Overgrowth and Fetal Growth Restriction. Obstet Gynecol Clin North Am. 2021 Jun; 48(2):247-266.
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White A, Stremming J, Boehmer BH, Chang EI, Jonker SS, Wesolowski SR, Brown LD, Rozance PJ. Reduced glucose-stimulated insulin secretion following a 1-wk IGF-1 infusion in late gestation fetal sheep is due to an intrinsic islet defect. Am J Physiol Endocrinol Metab. 2021 06 01; 320(6):E1138-E1147.
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Castillo-Castrejon M, Yang IV, Davidson EJ, Borengasser SJ, Jambal P, Westcott J, Kemp JF, Garces A, Ali SA, Saleem S, Goldenberg RL, Figueroa L, Hambidge KM, Krebs NF, Powell TL. Preconceptional Lipid-Based Nutrient Supplementation in 2 Low-Resource Countries Results in Distinctly Different IGF-1/mTOR Placental Responses. J Nutr. 2021 03 11; 151(3):556-569.
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Stremming J, Heard S, White A, Chang EI, Shaw SC, Wesolowski SR, Jonker SS, Rozance PJ, Brown LD. IGF-1 infusion to fetal sheep increases organ growth but not by stimulating nutrient transfer to the fetus. Am J Physiol Endocrinol Metab. 2021 03 01; 320(3):E527-E538.
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Keleher MR, Erickson K, Smith HA, Kechris KJ, Yang IV, Dabelea D, Friedman JE, Boyle KE, Jansson T. Placental Insulin/IGF-1 Signaling, PGC-1a, and Inflammatory Pathways Are Associated With Metabolic Outcomes at 4-6 Years of Age: The ECHO Healthy Start Cohort. Diabetes. 2021 03; 70(3):745-751.
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Ali A, Swanepoel CM, Winger QA, Rozance PJ, Anthony RV. Chorionic somatomammotropin RNA interference alters fetal liver glucose utilization. J Endocrinol. 2020 12; 247(3):251-262.
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Jonker SS, Giraud GD, Chang EI, Elman MR, Louey S. Coronary vascular growth matches IGF-1-stimulated cardiac growth in fetal sheep. FASEB J. 2020 08; 34(8):10041-10055.
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Seedorf G, Kim C, Wallace B, Mandell EW, Nowlin T, Shepherd D, Abman SH. rhIGF-1/BP3 Preserves Lung Growth and Prevents Pulmonary Hypertension in Experimental Bronchopulmonary Dysplasia. Am J Respir Crit Care Med. 2020 05 01; 201(9):1120-1134.
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Kelly AC, Powell TL, Jansson T. Placental function in maternal obesity. Clin Sci (Lond). 2020 04 30; 134(8):961-984.
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