Glucosylceramidase
"Glucosylceramidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high concentrations of glucosylceramide in the brain in GAUCHER DISEASE. EC 3.2.1.45.
| Descriptor ID |
D005962
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| MeSH Number(s) |
D08.811.277.450.420.412
|
| Concept/Terms |
Glucosylceramidase- Glucosylceramidase
- beta-Glucocerebrosidase
- beta Glucocerebrosidase
- Acid beta-Glucosidase
- Acid beta Glucosidase
- beta-Glucosidase, Acid
- Glucocerebroside beta-Glucosidase
- Glucocerebroside beta Glucosidase
- beta-Glucosidase, Glucocerebroside
- Glucosylceramide beta-Glucosidase
- Glucosylceramide beta Glucosidase
- beta-Glucosidase, Glucosylceramide
- Glucosylsphingosine Glucosyl Hydrolase
- Glucosyl Hydrolase, Glucosylsphingosine
- Hydrolase, Glucosylsphingosine Glucosyl
- Glucosyl Ceramidase
- Ceramidase, Glucosyl
- Glucocerebrosidase
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Below are MeSH descriptors whose meaning is more general than "Glucosylceramidase".
Below are MeSH descriptors whose meaning is more specific than "Glucosylceramidase".
This graph shows the total number of publications written about "Glucosylceramidase" by people in this website by year, and whether "Glucosylceramidase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 2 | 0 | 2 |
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Below are the most recent publications written about "Glucosylceramidase" by people in Profiles.
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Goebl A, Ferrier RA, Ferreira P, Pinto-Rojas A, Matshes E, Choy FY. Gaucher disease with prenatal onset and perinatal death due to compound heterozygosity for the missense R131C and null Rec Nci I GBA mutations. Pediatr Dev Pathol. 2011 May-Jun; 14(3):240-3.
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Ong DS, Mu TW, Palmer AE, Kelly JW. Endoplasmic reticulum Ca2+ increases enhance mutant glucocerebrosidase proteostasis. Nat Chem Biol. 2010 Jun; 6(6):424-32.