 Hypoxanthine
"Hypoxanthine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A purine and a reaction intermediate in the metabolism of adenosine and in the formation of nucleic acids by the salvage pathway.
| Descriptor ID |
D019271
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| MeSH Number(s) |
D03.633.100.759.758.399.475
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hypoxanthine".
Below are MeSH descriptors whose meaning is more specific than "Hypoxanthine".
This graph shows the total number of publications written about "Hypoxanthine" by people in this website by year, and whether "Hypoxanthine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hypoxanthine" by people in Profiles.
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Lee JS, Wang RX, Alexeev EE, Lanis JM, Battista KD, Glover LE, Colgan SP. Hypoxanthine is a checkpoint stress metabolite in colonic epithelial energy modulation and barrier function. J Biol Chem. 2018 04 20; 293(16):6039-6051.
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Nemkov T, Sun K, Reisz JA, Song A, Yoshida T, Dunham A, Wither MJ, Francis RO, Roach RC, Dzieciatkowska M, Rogers SC, Doctor A, Kriebardis A, Antonelou M, Papassideri I, Young CT, Thomas TA, Hansen KC, Spitalnik SL, Xia Y, Zimring JC, Hod EA, D'Alessandro A. Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storage. Haematologica. 2018 02; 103(2):361-372.
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Mitchell DG, Rosen GM, Tseitlin M, Symmes B, Eaton SS, Eaton GR. Use of rapid-scan EPR to improve detection sensitivity for spin-trapped radicals. Biophys J. 2013 Jul 16; 105(2):338-42.
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Beaudin AE, Perry CA, Stabler SP, Allen RH, Stover PJ. Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice. Am J Clin Nutr. 2012 Apr; 95(4):882-91.
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Patro JN, Urban M, Kuchta RD. Interaction of human DNA polymerase alpha and DNA polymerase I from Bacillus stearothermophilus with hypoxanthine and 8-oxoguanine nucleotides. Biochemistry. 2009 Sep 01; 48(34):8271-8.
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Batey RT, Gilbert SD, Montange RK. Structure of a natural guanine-responsive riboswitch complexed with the metabolite hypoxanthine. Nature. 2004 Nov 18; 432(7015):411-5.
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Inan C, Kilin? K, Kotiloglu E, Akman HO, Kili? I, Michl J. Antioxidant therapy of cobalt and vitamin E in hemosiderosis. J Lab Clin Med. 1998 Aug; 132(2):157-65.
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Palombo JD, Pomposelli JJ, Fechner KD, Blackburn GL, Bistrian BR. Enhanced restoration of adenine nucleotides in rat liver following extended preservation in UW solution by provision of adenosine during reperfusion. Transplantation. 1991 Apr; 51(4):867-73.
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