1-Methyl-3-isobutylxanthine
"1-Methyl-3-isobutylxanthine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
Descriptor ID |
D015056
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MeSH Number(s) |
D03.633.100.759.758.824.751.500
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Concept/Terms |
1-Methyl-3-isobutylxanthine- 1-Methyl-3-isobutylxanthine
- 1 Methyl 3 isobutylxanthine
- IBMX
- Isobutyltheophylline
- 3-Isobutyl-1-methylxanthine
- 3 Isobutyl 1 methylxanthine
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Below are MeSH descriptors whose meaning is more general than "1-Methyl-3-isobutylxanthine".
Below are MeSH descriptors whose meaning is more specific than "1-Methyl-3-isobutylxanthine".
This graph shows the total number of publications written about "1-Methyl-3-isobutylxanthine" by people in this website by year, and whether "1-Methyl-3-isobutylxanthine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 | 1996 | 0 | 3 | 3 | 1997 | 0 | 1 | 1 | 1999 | 0 | 3 | 3 | 2014 | 0 | 1 | 1 | 2017 | 0 | 1 | 1 | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "1-Methyl-3-isobutylxanthine" by people in Profiles.
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Nick HJ, Zeitlin PL, Yadav S, Bratcher PE. Measurements of spontaneous CFTR-mediated ion transport without acute channel activation in airway epithelial cultures after modulator exposure. Sci Rep. 2021 11 19; 11(1):22616.
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Sharpe EJ, Larson ED, Proenza C. Cyclic AMP reverses the effects of aging on pacemaker activity and If in sinoatrial node myocytes. J Gen Physiol. 2017 Feb; 149(2):237-247.
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Antunes G, Sebasti?o AM, Simoes de Souza FM. Mechanisms of regulation of olfactory transduction and adaptation in the olfactory cilium. PLoS One. 2014; 9(8):e105531.
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Schmidt EP, Damarla M, Rentsendorj O, Servinsky LE, Zhu B, Moldobaeva A, Gonzalez A, Hassoun PM, Pearse DB. Soluble guanylyl cyclase contributes to ventilator-induced lung injury in mice. Am J Physiol Lung Cell Mol Physiol. 2008 Dec; 295(6):L1056-65.
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Rich TC, Fagan KA, Tse TE, Schaack J, Cooper DM, Karpen JW. A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cell. Proc Natl Acad Sci U S A. 2001 Nov 06; 98(23):13049-54.
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Ogura T, Kinnamon SC. IP(3)-Independent release of Ca(2+) from intracellular stores: A novel mechanism for transduction of bitter stimuli. J Neurophysiol. 1999 Nov; 82(5):2657-66.
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Holwell TA, Schweitzer SC, Reyland ME, Evans RM. Vimentin-dependent utilization of LDL-cholesterol in human adrenal tumor cells is not associated with the level of expression of apoE, sterol carrier protein-2, or caveolin. J Lipid Res. 1999 Aug; 40(8):1440-52.
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Cathala L, Paupardin-Tritsch D. Effect of catecholamines on the hyperpolarization-activated cationic Ih and the inwardly rectifying potassium I(Kir) currents in the rat substantia nigra pars compacta. Eur J Neurosci. 1999 Feb; 11(2):398-406.
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Sheridan BC, McIntyre RC, Meldrum DR, Fullerton DA. Phosphodiesterase inhibition overcomes pulmonary vasomotor dysfunction in acute lung injury. J Surg Res. 1997 Aug; 71(2):145-9.
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Ogura T, Mackay-Sim A, Kinnamon SC. Bitter taste transduction of denatonium in the mudpuppy Necturus maculosus. J Neurosci. 1997 May 15; 17(10):3580-7.
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