 Myeloid Differentiation Factor 88
"Myeloid Differentiation Factor 88" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An intracellular signaling adaptor protein that plays a role in TOLL-LIKE RECEPTOR and INTERLEUKIN 1 RECEPTORS signal transduction. It forms a signaling complex with the activated cell surface receptors and members of the IRAK KINASES.
| Descriptor ID |
D053594
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| MeSH Number(s) |
D12.644.360.024.311 D12.776.157.057.074 D12.776.476.024.390
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| Concept/Terms |
Myeloid Differentiation Factor 88- Myeloid Differentiation Factor 88
- Toll-Like Receptor Signal Adaptor Protein MyD88
- Toll Like Receptor Signal Adaptor Protein MyD88
- MyD88 Protein
- TLR Signal Adaptor Protein MyD88
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Below are MeSH descriptors whose meaning is more general than "Myeloid Differentiation Factor 88".
Below are MeSH descriptors whose meaning is more specific than "Myeloid Differentiation Factor 88".
This graph shows the total number of publications written about "Myeloid Differentiation Factor 88" by people in this website by year, and whether "Myeloid Differentiation Factor 88" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2004 | 0 | 2 | 2 | | 2005 | 0 | 2 | 2 | | 2006 | 0 | 3 | 3 | | 2007 | 0 | 1 | 1 | | 2008 | 2 | 2 | 4 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 4 | 5 | | 2011 | 2 | 3 | 5 | | 2012 | 2 | 1 | 3 | | 2013 | 5 | 4 | 9 | | 2014 | 1 | 2 | 3 | | 2015 | 2 | 1 | 3 | | 2016 | 0 | 1 | 1 | | 2017 | 4 | 1 | 5 | | 2018 | 0 | 2 | 2 | | 2019 | 2 | 3 | 5 | | 2020 | 2 | 2 | 4 | | 2021 | 0 | 2 | 2 | | 2022 | 0 | 3 | 3 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Myeloid Differentiation Factor 88" by people in Profiles.
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Moreno DF, Fern?ndez de Larrea C. Clinical Implications of Genomic Profile in Waldenstr?m Macroglobulinemia. Hematol Oncol Clin North Am. 2023 08; 37(4):659-670.
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Moreno DF, L?pez-Guerra M, Paz S, Oliver-Cald?s A, Mena MP, Correa JG, Battram AM, Osuna M, Rivas-Delgado A, Rodr?guez-Lobato LG, Card?s O, Tovar N, Cibeira MT, Jim?nez-Segura R, Blad? J, Rosi?ol L, Colomer D, Fern?ndez de Larrea C. Prognostic impact of MYD88 and CXCR4 mutations assessed by droplet digital polymerase chain reaction in IgM monoclonal gammopathy of undetermined significance and smouldering Waldenstr?m macroglobulinaemia. Br J Haematol. 2023 01; 200(2):187-196.
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Moreno DF, de Larrea CF, Castillo JJ. New treatment strategies for Waldenstr?m macroglobulinemia. Clin Adv Hematol Oncol. 2022 Aug; 20(8):506-515.
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Kopecky BJ, Dun H, Amrute JM, Lin CY, Bredemeyer AL, Terada Y, Bayguinov PO, Koenig AL, Frye CC, Fitzpatrick JAJ, Kreisel D, Lavine KJ. Donor Macrophages Modulate Rejection After Heart Transplantation. Circulation. 2022 08 23; 146(8):623-638.
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Mysore V, Cullere X, Mears J, Rosetti F, Okubo K, Liew PX, Zhang F, Madera-Salcedo I, Rosenbauer F, Stone RM, Aster JC, von Andrian UH, Lichtman AH, Raychaudhuri S, Mayadas TN. Fc?R engagement reprograms neutrophils into antigen cross-presenting cells that elicit acquired anti-tumor immunity. Nat Commun. 2021 08 09; 12(1):4791.
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Ciavattone NG, Wu L, O'Neill R, Qiu J, Davila E, Cao X. MyD88 Costimulation in Donor CD8+ T Cells Enhances the Graft-versus-Tumor Effect in Murine Hematopoietic Cell Transplantation. J Immunol. 2021 02 15; 206(4):892-903.
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Gergen AK, Kohtz PD, Halpern AL, White AM, Meng X, Fullerton DA, Weyant MJ. Statins Inhibit Toll-Like Receptor 4-Mediated Growth of Human Esophageal Adenocarcinoma Cells. J Surg Res. 2021 04; 260:436-447.
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Genardi S, Visvabharathy L, Cao L, Morgun E, Cui Y, Qi C, Chen YH, Gapin L, Berdyshev E, Wang CR. Type II Natural Killer T Cells Contribute to Protection Against Systemic Methicillin-Resistant Staphylococcus aureus Infection. Front Immunol. 2020; 11:610010.
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Lee FF, Davidson K, Harris C, McClendon J, Janssen WJ, Alper S. NF-?B mediates lipopolysaccharide-induced alternative pre-mRNA splicing of MyD88 in mouse macrophages. J Biol Chem. 2020 05 01; 295(18):6236-6248.
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McCarthy MK, Reynoso GV, Winkler ES, Mack M, Diamond MS, Hickman HD, Morrison TE. MyD88-dependent influx of monocytes and neutrophils impairs lymph node B cell responses to chikungunya virus infection via Irf5, Nos2 and Nox2. PLoS Pathog. 2020 01; 16(1):e1008292.
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