Basement Membrane
"Basement Membrane" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers.
Descriptor ID |
D001485
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MeSH Number(s) |
A10.272.220 A10.615.179
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Concept/Terms |
Basement Membrane- Basement Membrane
- Basement Membranes
- Membrane, Basement
- Membranes, Basement
Basal Lamina- Basal Lamina
- Basal Laminas
- Lamina, Basal
- Laminas, Basal
- Basement Lamina
- Basement Laminas
- Lamina, Basement
- Laminas, Basement
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Below are MeSH descriptors whose meaning is more general than "Basement Membrane".
Below are MeSH descriptors whose meaning is more specific than "Basement Membrane".
This graph shows the total number of publications written about "Basement Membrane" by people in this website by year, and whether "Basement Membrane" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 | 1999 | 0 | 1 | 1 | 2000 | 0 | 1 | 1 | 2003 | 0 | 1 | 1 | 2004 | 0 | 2 | 2 | 2005 | 0 | 3 | 3 | 2007 | 1 | 0 | 1 | 2010 | 1 | 0 | 1 | 2012 | 0 | 1 | 1 | 2016 | 0 | 1 | 1 | 2018 | 0 | 1 | 1 | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Basement Membrane" by people in Profiles.
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Sprague KA, Sivesind TE, Szeto MD, Dellavalle RP, Kirtschig G. From the Cochrane Library: Interventions for mucous membrane pemphigoid and epidermolysis bullosa acquisita. J Am Acad Dermatol. 2022 06; 86(6):e273-e274.
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Zhang C, Lai MB, Pedler MG, Johnson V, Adams RH, Petrash JM, Chen Z, Junge HJ. Endothelial Cell-Specific Inactivation of TSPAN12 (Tetraspanin 12) Reveals Pathological Consequences of Barrier Defects in an Otherwise Intact Vasculature. Arterioscler Thromb Vasc Biol. 2018 11; 38(11):2691-2705.
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Lakshmanachetty S, Koster MI. Emerging roles for collagen XV and XVIII in cancer progression. Exp Dermatol. 2016 05; 25(5):346-7.
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Raghavan CT, Smuda M, Smith AJ, Howell S, Smith DG, Singh A, Gupta P, Glomb MA, Wormstone IM, Nagaraj RH. AGEs in human lens capsule promote the TGFß2-mediated EMT of lens epithelial cells: implications for age-associated fibrosis. Aging Cell. 2016 06; 15(3):465-76.
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O'Brien JH, Vanderlinden LA, Schedin PJ, Hansen KC. Rat mammary extracellular matrix composition and response to ibuprofen treatment during postpartum involution by differential GeLC-MS/MS analysis. J Proteome Res. 2012 Oct 05; 11(10):4894-905.
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Hecht JH, Siegenthaler JA, Patterson KP, Pleasure SJ. Primary cellular meningeal defects cause neocortical dysplasia and dyslamination. Ann Neurol. 2010 Oct; 68(4):454-64.
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Nakagawa T, Kosugi T, Haneda M, Rivard CJ, Long DA. Abnormal angiogenesis in diabetic nephropathy. Diabetes. 2009 Jul; 58(7):1471-8.
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Itty S, Hamilton SS, Baratz KH, Diehl NN, Maguire LJ. Outcomes of epithelial debridement for anterior basement membrane dystrophy. Am J Ophthalmol. 2007 Aug; 144(2):217-221.
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VanDeVoorde R, Witte D, Kogan J, Goebel J. Pierson syndrome: a novel cause of congenital nephrotic syndrome. Pediatrics. 2006 Aug; 118(2):e501-5.
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Jiang T, Liebman SE, Lucia MS, Li J, Levi M. Role of altered renal lipid metabolism and the sterol regulatory element binding proteins in the pathogenesis of age-related renal disease. Kidney Int. 2005 Dec; 68(6):2608-20.
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