 Antifibrinolytic Agents
"Antifibrinolytic Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that prevent fibrinolysis or lysis of a blood clot or thrombus. Several endogenous antiplasmins are known. The drugs are used to control massive hemorrhage and in other coagulation disorders.
| Descriptor ID |
D000933
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| MeSH Number(s) |
D27.505.519.421.500 D27.505.954.502.270.463.091
|
| Concept/Terms |
Plasmin Inhibitors- Plasmin Inhibitors
- Inhibitors, Plasmin
- Antiplasmins
- Plasmin Inhibitor
- Inhibitor, Plasmin
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Below are MeSH descriptors whose meaning is more general than "Antifibrinolytic Agents".
Below are MeSH descriptors whose meaning is more specific than "Antifibrinolytic Agents".
This graph shows the total number of publications written about "Antifibrinolytic Agents" by people in this website by year, and whether "Antifibrinolytic Agents" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 | | 2001 | 2 | 0 | 2 | | 2006 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2013 | 3 | 0 | 3 | | 2014 | 1 | 1 | 2 | | 2015 | 2 | 0 | 2 | | 2016 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 3 | 5 | 8 | | 2020 | 2 | 2 | 4 |
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Below are the most recent publications written about "Antifibrinolytic Agents" by people in Profiles.
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Barrett CD, Vigneshwar N, Moore HB, Ghasabyan A, Chandler J, Moore EE, Yaffe MB. Tranexamic acid is associated with reduced complement activation in trauma patients with hemorrhagic shock and hyperfibrinolysis on thromboelastography. Blood Coagul Fibrinolysis. 2020 Dec; 31(8):578-582.
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Barrett CD, Moore HB, Vigneshwar N, Dhara S, Chandler J, Chapman MP, Sauaia A, Moore EE, Yaffe MB. Plasmin thrombelastography rapidly identifies trauma patients at risk for massive transfusion, mortality, and hyperfibrinolysis: A diagnostic tool to resolve an international debate on tranexamic acid? J Trauma Acute Care Surg. 2020 12; 89(6):991-998.
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Wu TB, Orfeo T, Moore HB, Sumislawski JJ, Cohen MJ, Petzold LR. Computational model of tranexamic acid on urokinase mediated fibrinolysis. PLoS One. 2020; 15(5):e0233640.
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Coleman JR, Moore EE, Moore HB, Chapman MP, Cohen MJ, Silliman CC, Sauaia A. Tranexamic acid disturbs the dynamics of postinjury fibrinolysis. ANZ J Surg. 2020 04; 90(4):420-422.
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Walsh SLF, Lederer DJ, Ryerson CJ, Kolb M, Maher TM, Nusser R, Poletti V, Richeldi L, Vancheri C, Wilsher ML, Antoniou KM, Behr J, Bendstrup E, Brown KK, Corte TJ, Cottin V, Crestani B, Flaherty KR, Glaspole IN, Grutters J, Inoue Y, Kondoh Y, Kreuter M, Johannson KA, Ley B, Martinez FJ, Molina-Molina M, Morais A, Nunes H, Raghu G, Selman M, Spagnolo P, Taniguchi H, Tomassetti S, Valeyre D, Wijsenbeek M, Wuyts WA, Wells AU. Diagnostic Likelihood Thresholds That Define a Working Diagnosis of Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2019 11 01; 200(9):1146-1153.
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Fisher AD, Carius BM, April MD, Naylor JF, Maddry JK, Schauer SG. An Analysis of Adherence to Tactical Combat Casualty Care Guidelines for the Administration of Tranexamic Acid. J Emerg Med. 2019 Nov; 57(5):646-652.
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Moore HB, Neeves KB. Tranexamic acid for trauma: Repackaged and redelivered. J Thromb Haemost. 2019 10; 17(10):1626-1628.
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Santermans E, Ford P, Kreuter M, Verbruggen N, Meyvisch P, Wuyts WA, Brown KK, Lederer DJ, Byrne AJ, Molyneaux PL, Sivananthan A, Moor CC, Maher TM, Wijsenbeek M. Modelling Forced Vital Capacity in Idiopathic Pulmonary Fibrosis: Optimising Trial Design. Adv Ther. 2019 11; 36(11):3059-3070.
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Moore HB, Moore BA, Sauaia A, Moore EE. Clinical relevance and practical assessment of fibrinolysis shutdown. ANZ J Surg. 2020 04; 90(4):413-414.
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Nguyen TT, Lam HV, Austin TM, Stricker P, Tunceroglu H, Schoenecker J. Comparison of different dosage regimes of epsilon aminocaproic acid on blood loss in children undergoing craniosynostosis surgery. Paediatr Anaesth. 2019 08; 29(8):858-864.
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