 Antifibrinolytic Agents
"Antifibrinolytic Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that prevent fibrinolysis or lysis of a blood clot or thrombus. Several endogenous antiplasmins are known. The drugs are used to control massive hemorrhage and in other coagulation disorders.
| Descriptor ID |
D000933
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| MeSH Number(s) |
D27.505.519.421.500 D27.505.954.502.270.463.091
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| Concept/Terms |
Plasmin Inhibitors- Plasmin Inhibitors
- Inhibitors, Plasmin
- Antiplasmins
- Plasmin Inhibitor
- Inhibitor, Plasmin
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Below are MeSH descriptors whose meaning is more general than "Antifibrinolytic Agents".
Below are MeSH descriptors whose meaning is more specific than "Antifibrinolytic Agents".
This graph shows the total number of publications written about "Antifibrinolytic Agents" by people in this website by year, and whether "Antifibrinolytic Agents" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 | | 2001 | 2 | 0 | 2 | | 2006 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 2 | 1 | 3 | | 2015 | 1 | 0 | 1 | | 2017 | 0 | 2 | 2 | | 2018 | 1 | 0 | 1 | | 2019 | 2 | 3 | 5 | | 2021 | 1 | 0 | 1 | | 2022 | 2 | 0 | 2 | | 2023 | 6 | 0 | 6 | | 2024 | 1 | 1 | 2 | | 2025 | 5 | 1 | 6 |
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Below are the most recent publications written about "Antifibrinolytic Agents" by people in Profiles.
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Dixon JM, Wogu AF, Rodriguez MD, Barnhart D, Patel R, Lategan HJ, Oosthuizen G, Verster J, de Vries S, Wylie C, Erasmus E, Schauer SG, Mould-Millman NK. Mortality Benefit of Tranexamic Acid for Hemorrhage With Concurrent Traumatic Brain Injury: Outcomes From a Prospective Cohort Study in a High-Trauma, Prolonged Care Setting. World J Surg. 2026 Jan; 50(1):233-243.
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Stoner AK, Pezzanite LM, Dow SW, Alfonso NA, McGilvray KC. An In Vitro Assessment of a Biopolymer-Based Medical Foam for Enhanced Antifibrinolytic and Infection Prophylaxis for Acute Wound Management. ACS Appl Bio Mater. 2025 Dec 15; 8(12):10878-10889.
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Padilla CC, Farid M, Smith P, Darko K, O'Leary S, Levy B, Barrie U, Khan H, Aoun SG, Harter DH. Comparative Efficacy of Perioperative Blood Conservation Agents in Pediatric Cranial Vault Remodeling: A Systematic Review and Network Meta-Analysis. Neurosurgery. 2026 Mar 01; 98(3):510-519.
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Barrett WJ, Kaucher KA, Orpet RE, Campion EM, Goodloe JM, Fischer P, Colwell CB, Lyng JW. Tranexamic Acid in Trauma. Ann Emerg Med. 2025 Sep; 86(3):e73-e80.
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Barrett WJ, Kaucher KA, Orpet RE, Campion EM, Goodloe JM, Fischer PE, Colwell CB, Lyng JW. Tranexamic acid in trauma: A joint position statement and resource document of NAEMSP, ACEP, and ACS-COT. J Trauma Acute Care Surg. 2025 09 01; 99(3):357-363.
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Wogu AF, Dixon JM, Xiao M, Lategan HJ, Oosthuizen G, Schauer SG, Steyn E, Bhaumik S, Verster J, Wylie C, de Vries S, Mayet M, Hodsdon L, Wagner L, Snyders LO, Doubell K, Lourens D, Stassen W, Rees C, Young J, Moore EE, Mould-Millman NK. Tranexamic acid is associated with post-injury mortality in a resource-limited trauma system: Findings from the epidemiology and outcomes of prolonged trauma care cohort study. Transfusion. 2025 May; 65 Suppl 1:S276-S287.
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Hardin J, Seltzer J, Moriguchi R, Yeung K, Galust H, Corbett B, Schneir A, Clark RF, Suhandynata RT. Tranexamic Acid Neurotoxicity After Nebulization and BAL. Chest. 2024 Oct; 166(4):e101-e103.
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Adkins BD, Noland DK, Jacobs JW, Booth GS, Malicki D, Helander L, Jacquot C, Buscema G, Goel R, Andrews J, Lieberman L. Survey of pediatric massive transfusion protocol practice at United States level I trauma centers: An AABB Pediatric Transfusion Medicine Subsection study. Transfusion. 2024 10; 64(10):1860-1869.
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Huneault HE, Gent AE, Cohen CC, He Z, Jarrell ZR, Kamaleswaran R, Vos MB. Validation of a screening panel for pediatric metabolic dysfunction-associated steatotic liver disease using metabolomics. Hepatol Commun. 2024 03 01; 8(3).
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Haberkorn CJ, Severance CC, Wetmore NC, West WG, Ng PC, Cendali F, Pitotti C, Schauer SG, Maddry JK, Bebarta VS, Hendry-Hofer TB. Intramuscular administration of tranexamic acid in a large swine model of hemorrhage with hyperfibrinolysis. J Trauma Acute Care Surg. 2024 May 01; 96(5):735-741.
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