 Binding Sites
"Binding Sites" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The parts of a macromolecule that directly participate in its specific combination with another molecule.
| Descriptor ID |
D001665
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| MeSH Number(s) |
G02.111.570.120
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| Concept/Terms |
Binding Sites- Binding Sites
- Site, Binding
- Sites, Binding
- Binding Site
- Combining Site
- Combining Sites
- Site, Combining
- Sites, Combining
|
Below are MeSH descriptors whose meaning is more general than "Binding Sites".
Below are MeSH descriptors whose meaning is more specific than "Binding Sites".
This graph shows the total number of publications written about "Binding Sites" by people in this website by year, and whether "Binding Sites" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 0 | 18 | 18 | | 1990 | 0 | 16 | 16 | | 1991 | 0 | 17 | 17 | | 1992 | 0 | 19 | 19 | | 1993 | 0 | 21 | 21 | | 1994 | 0 | 26 | 26 | | 1995 | 0 | 25 | 25 | | 1996 | 0 | 41 | 41 | | 1997 | 0 | 49 | 49 | | 1998 | 0 | 33 | 33 | | 1999 | 1 | 25 | 26 | | 2000 | 0 | 42 | 42 | | 2001 | 0 | 48 | 48 | | 2002 | 0 | 52 | 52 | | 2003 | 0 | 60 | 60 | | 2004 | 0 | 52 | 52 | | 2005 | 0 | 45 | 45 | | 2006 | 2 | 58 | 60 | | 2007 | 0 | 37 | 37 | | 2008 | 0 | 47 | 47 | | 2009 | 0 | 27 | 27 | | 2010 | 1 | 33 | 34 | | 2011 | 2 | 48 | 50 | | 2012 | 0 | 43 | 43 | | 2013 | 0 | 34 | 34 | | 2014 | 0 | 35 | 35 | | 2015 | 0 | 23 | 23 | | 2016 | 2 | 38 | 40 | | 2017 | 0 | 37 | 37 | | 2018 | 1 | 19 | 20 |
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Below are the most recent publications written about "Binding Sites" by people in Profiles.
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Henen MA, Mahlawat P, Zwieb C, Kodali RB, Hinck CS, Hanna RD, Krzysiak TC, Ilangovan U, Cano KE, Hinck G, Vonberg M, McCabe M, Hinck AP. TGF-ß2 uses the concave surface of its extended finger region to bind betaglycan's ZP domain via three residues specific to TGF-ß and inhibin-a. J Biol Chem. 2019 03 01; 294(9):3065-3080.
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Fu X, Sokolova V, Webb KJ, Old W, Park S. Ubiquitin-dependent switch during assembly of the proteasomal ATPases mediated by Not4 ubiquitin ligase. Proc Natl Acad Sci U S A. 2018 12 26; 115(52):13246-13251.
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Romero Romero ML, Yang F, Lin YR, Toth-Petroczy A, Berezovsky IN, Goncearenco A, Yang W, Wellner A, Kumar-Deshmukh F, Sharon M, Baker D, Varani G, Tawfik DS. Simple yet functional phosphate-loop proteins. Proc Natl Acad Sci U S A. 2018 12 18; 115(51):E11943-E11950.
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Glustrom LW, Lyon KR, Paschini M, Reyes CM, Parsonnet NV, Toro TB, Lundblad V, Wuttke DS. Single-stranded telomere-binding protein employs a dual rheostat for binding affinity and specificity that drives function. Proc Natl Acad Sci U S A. 2018 10 09; 115(41):10315-10320.
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Melby ES, Allen C, Foreman-Ortiz IU, Caudill ER, Kuech TR, Vartanian AM, Zhang X, Murphy CJ, Hernandez R, Pedersen JA. Peripheral Membrane Proteins Facilitate Nanoparticle Binding at Lipid Bilayer Interfaces. Langmuir. 2018 09 11; 34(36):10793-10805.
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Singh R. A Novel Saturation Mutagenesis Approach: Single Step Characterization of Regulatory Protein Binding Sites in RNA Using Phosphorothioates. J Vis Exp. 2018 08 21; (138).
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Nguyen ED, Balas MM, Griffin AM, Roberts JT, Johnson AM. Global profiling of hnRNP A2/B1-RNA binding on chromatin highlights LncRNA interactions. RNA Biol. 2018; 15(7):901-913.
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Dinkel BA, Kremer KN, Rollins MR, Medlyn MJ, Hedin KE. GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation that drives PI3K?/PREX1 signaling and T cell cytokine secretion. J Biol Chem. 2018 09 07; 293(36):14022-14039.
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Tuttle KD, Krovi SH, Zhang J, Bedel R, Harmacek L, Peterson LK, Dragone LL, Lefferts A, Halluszczak C, Riemondy K, Hesselberth JR, Rao A, O'Connor BP, Marrack P, Scott-Browne J, Gapin L. TCR signal strength controls thymic differentiation of iNKT cell subsets. Nat Commun. 2018 07 09; 9(1):2650.
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Gulati S, Jin H, Masuho I, Orban T, Cai Y, Pardon E, Martemyanov KA, Kiser PD, Stewart PL, Ford CP, Steyaert J, Palczewski K. Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor. Nat Commun. 2018 05 18; 9(1):1996.
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