 Purpura, Thrombotic Thrombocytopenic
"Purpura, Thrombotic Thrombocytopenic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE.
| Descriptor ID |
D011697
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| MeSH Number(s) |
C15.378.100.802.687.680 C15.378.140.855.925.750.680 C15.378.925.850 C23.550.414.950.687.680 C23.888.885.687.687.680
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| Concept/Terms |
Purpura, Thrombotic Thrombocytopenic- Purpura, Thrombotic Thrombocytopenic
- Thrombocytopenic Purpura, Thrombotic
- Moschkowitz Disease
- Disease, Moschkowitz
- Thrombotic Thrombocytopenic Purpura
- Moschcowitz Disease
- Disease, Moschcowitz
- Purpura, Thrombotic Thrombopenic
- Thrombopenic Purpura, Thrombotic
- Thrombotic Thrombopenic Purpura
Congenital Thrombotic Thrombocytopenic Purpura- Congenital Thrombotic Thrombocytopenic Purpura
- Schulman-Upshaw Syndrome
- Schulman Upshaw Syndrome
- Syndrome, Schulman-Upshaw
- Upshaw-Schulman Syndrome
- Syndrome, Upshaw-Schulman
- Upshaw Schulman Syndrome
- Thrombotic Thrombocytopenic Purpura, Congenital
- Upshaw Factor, Deficiency of
- Microangiopathic Hemolytic Anemia, Congenital
- Thrombotic Microangiopathy, Familial
- Familial Thrombotic Microangiopathy
- Microangiopathy, Familial Thrombotic
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Below are MeSH descriptors whose meaning is more general than "Purpura, Thrombotic Thrombocytopenic".
- Diseases [C]
- Hemic and Lymphatic Diseases [C15]
- Hematologic Diseases [C15.378]
- Blood Coagulation Disorders [C15.378.100]
- Purpura [C15.378.100.802]
- Purpura, Thrombocytopenic [C15.378.100.802.687]
- Purpura, Thrombotic Thrombocytopenic [C15.378.100.802.687.680]
- Blood Platelet Disorders [C15.378.140]
- Thrombocytopenia [C15.378.140.855]
- Thrombotic Microangiopathies [C15.378.140.855.925]
- Purpura, Thrombocytopenic [C15.378.140.855.925.750]
- Purpura, Thrombotic Thrombocytopenic [C15.378.140.855.925.750.680]
- Thrombophilia [C15.378.925]
- Purpura, Thrombotic Thrombocytopenic [C15.378.925.850]
- Pathological Conditions, Signs and Symptoms [C23]
- Pathologic Processes [C23.550]
- Hemorrhage [C23.550.414]
- Purpura [C23.550.414.950]
- Purpura, Thrombocytopenic [C23.550.414.950.687]
- Purpura, Thrombotic Thrombocytopenic [C23.550.414.950.687.680]
- Signs and Symptoms [C23.888]
- Skin Manifestations [C23.888.885]
- Purpura [C23.888.885.687]
- Purpura, Thrombocytopenic [C23.888.885.687.687]
- Purpura, Thrombotic Thrombocytopenic [C23.888.885.687.687.680]
Below are MeSH descriptors whose meaning is more specific than "Purpura, Thrombotic Thrombocytopenic".
This graph shows the total number of publications written about "Purpura, Thrombotic Thrombocytopenic" by people in this website by year, and whether "Purpura, Thrombotic Thrombocytopenic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 2 | 2 | | 2019 | 3 | 0 | 3 | | 2021 | 2 | 0 | 2 | | 2022 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Purpura, Thrombotic Thrombocytopenic" by people in Profiles.
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Chaturvedi S, Antun AG, Farland AM, Woods R, Metjian A, Park YA, de Ridder G, Gibson B, Kasthuri RS, Liles DK, Akwaa F, Clover T, Baumann Kreuziger L, Sadler JE, Sridharan M, Go RS, McCrae KR, Upreti HV, Liu A, Lim MY, Gangaraju R, Zheng XL, Raval JS, Masias C, Cataland SR, Johnson A, Davis E, Evans MD, Mazepa MA. Race, rituximab, and relapse in TTP. Blood. 2022 09 22; 140(12):1335-1344.
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Costello A, Pandita A, Devitt J. Case Report: Thrombotic Thrombocytopenia after COVID-19 Janssen Vaccination. Am Fam Physician. 2021 06 01; 103(11):646-647.
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Peyvandi F, Cataland S, Scully M, Coppo P, Knoebl P, Kremer Hovinga JA, Metjian A, de la Rubia J, Pavenski K, Minkue Mi Edou J, De Winter H, Callewaert F. Caplacizumab prevents refractoriness and mortality in acquired thrombotic thrombocytopenic purpura: integrated analysis. Blood Adv. 2021 04 27; 5(8):2137-2141.
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Knoebl P, Cataland S, Peyvandi F, Coppo P, Scully M, Kremer Hovinga JA, Metjian A, de la Rubia J, Pavenski K, Minkue Mi Edou J, De Winter H, Callewaert F. Efficacy and safety of open-label caplacizumab in patients with exacerbations of acquired thrombotic thrombocytopenic purpura in the HERCULES study. J Thromb Haemost. 2020 02; 18(2):479-484.
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Zwicker JI, Muia J, Dolatshahi L, Westfield LA, Nieters P, Rodrigues A, Hamdan A, Antun AG, Metjian A, Sadler JE. Adjuvant low-dose rituximab and plasma exchange for acquired TTP. Blood. 2019 09 26; 134(13):1106-1109.
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Thumma S, Idrees S, Phuyal P, Manchala V, Mattana J. When the Standard Treatment Fails: Rituximab Therapy for Refractory TTP. Am J Ther. 2019 Jul/Aug; 26(4):e552-e553.
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Scully M, Cataland SR, Peyvandi F, Coppo P, Knöbl P, Kremer Hovinga JA, Metjian A, de la Rubia J, Pavenski K, Callewaert F, Biswas D, De Winter H, Zeldin RK. Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura. N Engl J Med. 2019 01 24; 380(4):335-346.
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Vaught AJ, Braunstein EM, Jasem J, Yuan X, Makhlin I, Eloundou S, Baines AC, Merrill SA, Chaturvedi S, Blakemore K, Sperati CJ, Brodsky RA. Germline mutations in the alternative pathway of complement predispose to HELLP syndrome. JCI Insight. 2018 03 22; 3(6).
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Thurman JM. A Patient with Hemolytic Uremic Syndrome and Kidney Failure. Clin J Am Soc Nephrol. 2018 06 07; 13(6):933-936.
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Tanhehco YC, Arepally G, Metjian A. Novel therapeutic approaches for thrombotic thrombocytopenic purpura. Curr Opin Hematol. 2017 Nov; 24(6):521-528.
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