 Cyclization
"Cyclization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
| Descriptor ID |
D003500
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| MeSH Number(s) |
G02.111.180 G02.607.133 G03.208
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cyclization".
Below are MeSH descriptors whose meaning is more specific than "Cyclization".
This graph shows the total number of publications written about "Cyclization" by people in this website by year, and whether "Cyclization" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 2 | 2 | | 2007 | 0 | 3 | 3 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 2 | 2 | | 2010 | 0 | 4 | 4 | | 2011 | 0 | 3 | 3 | | 2012 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclization" by people in Profiles.
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Qiao Z, Xu J, Gonzalez R, Miao Y. Novel [99mTc]-Tricarbonyl-NOTA-Conjugated Lactam-Cyclized Alpha-MSH Peptide with Enhanced Melanoma Uptake and Reduced Renal Uptake. Mol Pharm. 2020 09 08; 17(9):3581-3588.
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Yang J, Xu J, Cheuy L, Gonzalez R, Fisher DR, Miao Y. Evaluation of a Novel Pb-203-Labeled Lactam-Cyclized Alpha-Melanocyte-Stimulating Hormone Peptide for Melanoma Targeting. Mol Pharm. 2019 04 01; 16(4):1694-1702.
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Yi D, Zhu F, Walczak MA. Stereoretentive Intramolecular Glycosyl Cross-Coupling: Development, Scope, and Kinetic Isotope Effect Study. Org Lett. 2018 08 03; 20(15):4627-4631.
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He W, Griffiths BM, Wang W, Wang X. Diastereoselective synthesis and biological evaluation of enantiomerically pure tricyclic indolines. Org Biomol Chem. 2017 May 16; 15(19):4241-4245.
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Liu L, Xu J, Yang J, Feng C, Miao Y. Imaging human melanoma using a novel Tc-99m-labeled lactam bridge-cyclized alpha-MSH peptide. Bioorg Med Chem Lett. 2016 10 01; 26(19):4724-4728.
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Guo H, Miao Y. Introduction of an 8-aminooctanoic acid linker enhances uptake of 99mTc-labeled lactam bridge-cyclized a-MSH peptide in melanoma. J Nucl Med. 2014 Dec; 55(12):2057-63.
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Feula A, Dhillon SS, Byravan R, Sangha M, Ebanks R, Salih MA, Spencer N, Male L, Magyary I, Deng WP, Müller F, Fossey JS. Synthesis of azetidines and pyrrolidines via iodocyclisation of homoallyl amines and exploration of activity in a zebrafish embryo assay. Org Biomol Chem. 2013 Aug 21; 11(31):5083-93.
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Guo H, Gallazzi F, Miao Y. Gallium-67-labeled lactam bridge-cyclized alpha-MSH peptides with enhanced melanoma uptake and reduced renal uptake. Bioconjug Chem. 2012 Jun 20; 23(6):1341-8.
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Gazaille JA, Abramite JA, Sammakia T. Toward the synthesis of (+)-peloruside A via an intramolecular vinylogous aldol reaction. Org Lett. 2012 Jan 06; 14(1):178-81.
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Guo H, Yang J, Gallazzi F, Miao Y. Effects of the amino acid linkers on the melanoma-targeting and pharmacokinetic properties of 111In-labeled lactam bridge-cyclized alpha-MSH peptides. J Nucl Med. 2011 Apr; 52(4):608-16.
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