 Potassium Channel Blockers
"Potassium Channel Blockers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS.
| Descriptor ID |
D026902
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| MeSH Number(s) |
D27.505.519.562.500 D27.505.954.411.645
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Potassium Channel Blockers".
Below are MeSH descriptors whose meaning is more specific than "Potassium Channel Blockers".
This graph shows the total number of publications written about "Potassium Channel Blockers" by people in this website by year, and whether "Potassium Channel Blockers" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 1 | 1 | 2 | | 2001 | 1 | 1 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 2 | 2 | 4 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 1 | 2 | 3 | | 2013 | 0 | 1 | 1 | | 2014 | 0 | 3 | 3 | | 2015 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Potassium Channel Blockers" by people in Profiles.
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Tseng KC, Li H, Clark A, Sundem L, Zuscik M, Noble M, Elfar J. 4-Aminopyridine promotes functional recovery and remyelination in acute peripheral nerve injury. EMBO Mol Med. 2016 12; 8(12):1409-1420.
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Holdsworth CT, Ferguson SK, Poole DC, Musch TI. Modulation of rat skeletal muscle microvascular O2 pressure via KATP channel inhibition following the onset of contractions. Respir Physiol Neurobiol. 2016 Feb 01; 222:48-54.
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Shiraishi T, Tamura Y, Taniguchi K, Higaki M, Ueda S, Shima T, Nagura M, Nakagawa T, Johnson RJ, Uchida S. Combination of ACE inhibitor with nicorandil provides further protection in chronic kidney disease. Am J Physiol Renal Physiol. 2014 Dec 15; 307(12):F1313-22.
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Meredith FL, Rennie KJ. Zonal variations in K+ currents in vestibular crista calyx terminals. J Neurophysiol. 2015 Jan 01; 113(1):264-76.
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Song Z, Levin BE, Stevens W, Sladek CD. Supraoptic oxytocin and vasopressin neurons function as glucose and metabolic sensors. Am J Physiol Regul Integr Comp Physiol. 2014 Apr 01; 306(7):R447-56.
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Mann SE, Johnson M, Meredith FL, Rennie KJ. Inhibition of K+ currents in type I vestibular hair cells by gentamicin and neomycin. Audiol Neurootol. 2013; 18(5):317-26.
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Egeberg MD, Oh CY, Bainbridge JL. Clinical overview of dalfampridine: an agent with a novel mechanism of action to help with gait disturbances. Clin Ther. 2012 Nov; 34(11):2185-94.
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Brunt VE, Minson CT. KCa channels and epoxyeicosatrienoic acids: major contributors to thermal hyperaemia in human skin. J Physiol. 2012 Aug 01; 590(15):3523-34.
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Sarraf M, Lu L, Ye S, Reiter MJ, Greyson CR, Schwartz GG. Thiazolidinedione drugs promote onset, alter characteristics, and increase mortality of ischemic ventricular fibrillation in pigs. Cardiovasc Drugs Ther. 2012 Jun; 26(3):195-204.
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Dabertrand F, Nelson MT, Brayden JE. Acidosis dilates brain parenchymal arterioles by conversion of calcium waves to sparks to activate BK channels. Circ Res. 2012 Jan 20; 110(2):285-94.
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