 Cytochrome P-450 CYP1A1
"Cytochrome P-450 CYP1A1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.
| Descriptor ID |
D019363
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| MeSH Number(s) |
D08.244.453.005.332 D08.244.453.100.500 D08.811.682.690.708.170.010.277 D08.811.682.690.708.170.020.500 D12.776.422.220.453.010.332 D12.776.422.220.453.100.500
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| Concept/Terms |
Cytochrome P-450 CYP1A1- Cytochrome P-450 CYP1A1
- Cytochrome P 450 CYP1A1
- EROD
- Ethoxyresorufin Dealkylase
- Ethylresorufin O-Deethylase
- CYP1A1 Protein
- 7-Ethoxyresorufin O-Deethylase
- CYP1A1
- Cytochrome P450 IA1
- Ethoxyresorufin O-Deethylase
- CYP 1A1
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Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 CYP1A1".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 CYP1A1".
This graph shows the total number of publications written about "Cytochrome P-450 CYP1A1" by people in this website by year, and whether "Cytochrome P-450 CYP1A1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cytochrome P-450 CYP1A1" by people in Profiles.
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Dolly A, P?tgens SA, Thibaut MM, Neyrinck AM, de Castro GS, Galbert C, Lefevre C, Wyart E, Gomes SP, Gon?alves DC, Lanthier N, Baldin P, Huot JR, Bonetto A, Seelaender M, Delzenne NM, Sokol H, Bindels LB. Impairment of aryl hydrocarbon receptor signalling promotes hepatic disorders in cancer cachexia. J Cachexia Sarcopenia Muscle. 2023 06; 14(3):1569-1582.
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Gupta A, Sasse SK, Gruca MA, Sanford L, Dowell RD, Gerber AN. Deconvolution of multiplexed transcriptional responses to wood smoke particles defines rapid aryl hydrocarbon receptor signaling dynamics. J Biol Chem. 2021 10; 297(4):101147.
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Baker JK, Long SM, Hassell KL, Pettigrove VJ, Gagnon MM. Health Status of Sand Flathead (Platycephalus bassensis), Inhabiting an Industrialised and Urbanised Embayment, Port Phillip Bay, Victoria as Measured by Biomarkers of Exposure and Effects. PLoS One. 2016; 11(10):e0164257.
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Harvey PA, Leinwand LA. Oestrogen enhances cardiotoxicity induced by Sunitinib by regulation of drug transport and metabolism. Cardiovasc Res. 2015 Jul 01; 107(1):66-77.
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Martin YN, Manlove L, Dong J, Carey WA, Thompson MA, Pabelick CM, Pandya HC, Martin RJ, Wigle DA, Prakash YS. Hyperoxia-induced changes in estradiol metabolism in postnatal airway smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2015 Jan 15; 308(2):L141-6.
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Vyhlidal CA, Riffel AK, Haley KJ, Sharma S, Dai H, Tantisira KG, Weiss ST, Leeder JS. Cotinine in human placenta predicts induction of gene expression in fetal tissues. Drug Metab Dispos. 2013 Feb; 41(2):305-11.
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Gramignoli R, Green ML, Tahan V, Dorko K, Skvorak KJ, Marongiu F, Zao W, Venkataramanan R, Ellis EC, Geller D, Breite AG, Dwulet FE, McCarthy RC, Strom SC. Development and application of purified tissue dissociation enzyme mixtures for human hepatocyte isolation. Cell Transplant. 2012; 21(6):1245-60.
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Singhal R, Shankar K, Badger TM, Ronis MJ. Estrogenic status modulates aryl hydrocarbon receptor--mediated hepatic gene expression and carcinogenicity. Carcinogenesis. 2008 Feb; 29(2):227-36.
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Anderson GR, Hasan A, Yin H, Qadri I, Quattrochi LC. Regulation of the CYP1A1 gene by 2,3,7,8-tetrachlorodibenzo-p-dioxin but not by beta-naphthoflavone or 3-methylcholanthrene is altered in hepatitis C virus replicon-expressing cells. Mol Pharmacol. 2006 Sep; 70(3):1062-70.
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