 Cyclosporine
"Cyclosporine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).
| Descriptor ID |
D016572
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| MeSH Number(s) |
D04.345.566.235.300 D12.644.641.235.300
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| Concept/Terms |
Cyclosporine- Cyclosporine
- Cyclosporin
- Cyclosporine A
- Ciclosporin
- Cyclosporin A
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Below are MeSH descriptors whose meaning is more general than "Cyclosporine".
Below are MeSH descriptors whose meaning is more specific than "Cyclosporine".
This graph shows the total number of publications written about "Cyclosporine" by people in this website by year, and whether "Cyclosporine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 7 | 0 | 7 | | 1992 | 4 | 4 | 8 | | 1993 | 5 | 4 | 9 | | 1994 | 7 | 0 | 7 | | 1995 | 3 | 3 | 6 | | 1996 | 12 | 2 | 14 | | 1997 | 6 | 6 | 12 | | 1998 | 0 | 5 | 5 | | 1999 | 8 | 5 | 13 | | 2000 | 7 | 6 | 13 | | 2001 | 10 | 6 | 16 | | 2002 | 5 | 2 | 7 | | 2003 | 3 | 5 | 8 | | 2004 | 3 | 6 | 9 | | 2005 | 5 | 4 | 9 | | 2006 | 2 | 1 | 3 | | 2007 | 2 | 1 | 3 | | 2008 | 0 | 4 | 4 | | 2009 | 3 | 4 | 7 | | 2010 | 5 | 4 | 9 | | 2011 | 2 | 0 | 2 | | 2012 | 4 | 5 | 9 | | 2013 | 4 | 1 | 5 | | 2014 | 0 | 2 | 2 | | 2015 | 0 | 2 | 2 | | 2016 | 1 | 6 | 7 | | 2018 | 2 | 2 | 4 | | 2019 | 3 | 0 | 3 |
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Below are the most recent publications written about "Cyclosporine" by people in Profiles.
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Sandmaier BM, Kornblit B, Storer BE, Olesen G, Maris MB, Langston AA, Gutman JA, Petersen SL, Chauncey TR, Bethge WA, Pulsipher MA, Woolfrey AE, Mielcarek M, Martin PJ, Appelbaum FR, Flowers MED, Maloney DG, Storb R. Addition of sirolimus to standard cyclosporine plus mycophenolate mofetil-based graft-versus-host disease prophylaxis for patients after unrelated non-myeloablative haemopoietic stem cell transplantation: a multicentre, randomised, phase 3 trial. Lancet Haematol. 2019 Aug; 6(8):e409-e418.
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Klawitter J, Klawitter J, Pennington A, Kirkpatrick B, Roda G, Kotecha NC, Thurman JM, Christians U. Cyclophilin D knockout protects the mouse kidney against cyclosporin A-induced oxidative stress. Am J Physiol Renal Physiol. 2019 09 01; 317(3):F683-F694.
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Rogers ZR, Nakano TA, Olson TS, Bertuch AA, Wang W, Gillio A, Coates TD, Chawla A, Castillo P, Kurre P, Gamper C, Bennett CM, Joshi S, Geddis AE, Boklan J, Nalepa G, Rothman JA, Huang JN, Kupfer GM, Cada M, Glader B, Walkovich KJ, Thompson AA, Hanna R, Vlachos A, Malsch M, Weller EA, Williams DA, Shimamura A. Immunosuppressive therapy for pediatric aplastic anemia: a North American Pediatric Aplastic Anemia Consortium study. Haematologica. 2019 10; 104(10):1974-1983.
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Plenter RJ, Grazia TJ, Coulombe MG, Nelsen MK, Lin CM, Scott Beard K, Kupfer TM, Zamora MR, Gill RG, Pietra BA. Anti-LFA-1 induces CD8 T-cell dependent allograft tolerance and augments suppressor phenotype CD8 cells. Cell Immunol. 2018 10; 332:101-110.
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Krishnamurthy A, Dasari A, Noonan AM, Mehnert JM, Lockhart AC, Leong S, Capasso A, Stein MN, Sanoff HK, Lee JJ, Hansen A, Malhotra U, Rippke S, Gustafson DL, Pitts TM, Ellison K, Davis SL, Messersmith WA, Eckhardt SG, Lieu CH. Phase Ib Results of the Rational Combination of Selumetinib and Cyclosporin A in Advanced Solid Tumors with an Expansion Cohort in Metastatic Colorectal Cancer. Cancer Res. 2018 09 15; 78(18):5398-5407.
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Woodward Z, Brooks P, Morris-Smith B, Wallis M, Ogbourne SM. Adsorption and Leachable Contamination of Flucloxacillin, Cyclosporin and Amiodarone Following Delivery Through an Intravenous Administration Set. Pharm Res. 2018 Apr 19; 35(6):121.
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Ronan PJ, Strait SA, Palmer GM, Beresford TP. Central Administration of Cyclosporine A Decreases Ethanol Drinking. Alcohol Alcohol. 2018 Mar 01; 53(2):193-199.
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Chang J, Graves SS, Butts-Miwongtum T, Sale GE, Storb R, Mathes DW. Long-term Tolerance Toward Haploidentical Vascularized Composite Allograft Transplantation in a Canine Model Using Bone Marrow or Mobilized Stem Cells. Transplantation. 2016 Dec; 100(12):e120-e127.
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Lamprecht DG, Todd BA, Denham AM, Ruppe LK, Stadler SL. Clinical Pharmacist Patient-Safety Initiative to Reduce Against-Label Prescribing of Statins With Cyclosporine. Ann Pharmacother. 2017 Feb; 51(2):140-145.
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Lu CC, Leng J, Cannon GW, Zhou X, Egger M, South B, Burningham Z, Zeng Q, Sauer BC. The use of natural language processing on narrative medication schedules to compute average weekly dose. Pharmacoepidemiol Drug Saf. 2016 12; 25(12):1414-1424.
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