 Cyclosporine
"Cyclosporine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).
| Descriptor ID |
D016572
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| MeSH Number(s) |
D04.345.566.235.300 D12.644.641.235.300
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| Concept/Terms |
Cyclosporine- Cyclosporine
- Cyclosporin
- Cyclosporine A
- Ciclosporin
- Cyclosporin A
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Below are MeSH descriptors whose meaning is more general than "Cyclosporine".
Below are MeSH descriptors whose meaning is more specific than "Cyclosporine".
This graph shows the total number of publications written about "Cyclosporine" by people in this website by year, and whether "Cyclosporine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 2 | 1 | 3 | | 1993 | 1 | 2 | 3 | | 1994 | 2 | 0 | 2 | | 1995 | 2 | 2 | 4 | | 1996 | 2 | 1 | 3 | | 1997 | 3 | 5 | 8 | | 1998 | 0 | 3 | 3 | | 1999 | 3 | 4 | 7 | | 2000 | 5 | 4 | 9 | | 2001 | 4 | 3 | 7 | | 2002 | 4 | 2 | 6 | | 2003 | 3 | 3 | 6 | | 2004 | 1 | 4 | 5 | | 2005 | 2 | 2 | 4 | | 2006 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 0 | 2 | 2 | | 2009 | 1 | 3 | 4 | | 2010 | 1 | 3 | 4 | | 2012 | 1 | 4 | 5 | | 2013 | 3 | 1 | 4 | | 2014 | 0 | 2 | 2 | | 2015 | 0 | 1 | 1 | | 2016 | 1 | 4 | 5 | | 2018 | 0 | 1 | 1 | | 2019 | 2 | 1 | 3 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclosporine" by people in Profiles.
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Watkins B, Qayed M, McCracken C, Bratrude B, Betz K, Suessmuth Y, Yu A, Sinclair S, Furlan S, Bosinger S, Tkachev V, Rhodes J, Tumlin AG, Narayan A, Cribbin K, Gillespie S, Gooley TA, Pasquini MC, Hebert K, Kapoor U, Rogatko A, Tighiouart M, Kim S, Bresee C, Choi SW, Davis J, Duncan C, Giller R, Grimley M, Harris AC, Jacobsohn D, Lalefar N, Norkin M, Farhadfar N, Pulsipher MA, Shenoy S, Petrovic A, Schultz KR, Yanik GA, Waller EK, Levine JE, Ferrara JL, Blazar BR, Langston A, Horan JT, Kean LS. Phase II Trial of Costimulation Blockade With Abatacept for Prevention of Acute GVHD. J Clin Oncol. 2021 06 10; 39(17):1865-1877.
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Plenter RJ, Coulombe MG, Roybal HM, Lin CM, Gill RG, Zamora MR, Grazia TJ. C-kit-derived CD11b+ cells are critical for cardiac allograft prolongation by autologous C-kit+ progenitor cells. Cell Immunol. 2020 01; 347:104023.
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Sandmaier BM, Kornblit B, Storer BE, Olesen G, Maris MB, Langston AA, Gutman JA, Petersen SL, Chauncey TR, Bethge WA, Pulsipher MA, Woolfrey AE, Mielcarek M, Martin PJ, Appelbaum FR, Flowers MED, Maloney DG, Storb R. Addition of sirolimus to standard cyclosporine plus mycophenolate mofetil-based graft-versus-host disease prophylaxis for patients after unrelated non-myeloablative haemopoietic stem cell transplantation: a multicentre, randomised, phase 3 trial. Lancet Haematol. 2019 Aug; 6(8):e409-e418.
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Klawitter J, Klawitter J, Pennington A, Kirkpatrick B, Roda G, Kotecha NC, Thurman JM, Christians U. Cyclophilin D knockout protects the mouse kidney against cyclosporin A-induced oxidative stress. Am J Physiol Renal Physiol. 2019 09 01; 317(3):F683-F694.
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Woodward Z, Brooks P, Morris-Smith B, Wallis M, Ogbourne SM. Adsorption and Leachable Contamination of Flucloxacillin, Cyclosporin and Amiodarone Following Delivery Through an Intravenous Administration Set. Pharm Res. 2018 Apr 19; 35(6):121.
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Chang J, Graves SS, Butts-Miwongtum T, Sale GE, Storb R, Mathes DW. Long-term Tolerance Toward Haploidentical Vascularized Composite Allograft Transplantation in a Canine Model Using Bone Marrow or Mobilized Stem Cells. Transplantation. 2016 Dec; 100(12):e120-e127.
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Lamprecht DG, Todd BA, Denham AM, Ruppe LK, Stadler SL. Clinical Pharmacist Patient-Safety Initiative to Reduce Against-Label Prescribing of Statins With Cyclosporine. Ann Pharmacother. 2017 Feb; 51(2):140-145.
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Bejanyan N, Rogosheske J, DeFor TE, Lazaryan A, Arora M, Holtan SG, Jacobson PA, MacMillan ML, Verneris MR, Blazar BR, Weisdorf DJ, Wagner JE, Brunstein CG. Sirolimus and Mycophenolate Mofetil as Calcineurin Inhibitor-Free Graft-versus-Host Disease Prophylaxis for Reduced-Intensity Conditioning Umbilical Cord Blood Transplantation. Biol Blood Marrow Transplant. 2016 11; 22(11):2025-2030.
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Gregory DG. New Grading System and Treatment Guidelines for the Acute Ocular Manifestations of Stevens-Johnson Syndrome. Ophthalmology. 2016 08; 123(8):1653-1658.
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Kimura-Ohba S, Yang Y, Thompson J, Kimura T, Salayandia VM, Cosse M, Yang Y, Sillerud LO, Rosenberg GA. Transient increase of fractional anisotropy in reversible vasogenic edema. J Cereb Blood Flow Metab. 2016 10; 36(10):1731-1743.
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