 Thymus Gland
"Thymus Gland" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A single, unpaired primary lymphoid organ situated in the MEDIASTINUM, extending superiorly into the neck to the lower edge of the THYROID GLAND and inferiorly to the fourth costal cartilage. It is necessary for normal development of immunologic function early in life. By puberty, it begins to involute and much of the tissue is replaced by fat.
| Descriptor ID |
D013950
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| MeSH Number(s) |
A10.549.750 A15.382.520.604.750
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| Concept/Terms |
Thymus Gland- Thymus Gland
- Gland, Thymus
- Glands, Thymus
- Thymus Glands
- Thymus
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Below are MeSH descriptors whose meaning is more general than "Thymus Gland".
Below are MeSH descriptors whose meaning is more specific than "Thymus Gland".
This graph shows the total number of publications written about "Thymus Gland" by people in this website by year, and whether "Thymus Gland" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 2 | 3 | 5 | | 1992 | 2 | 3 | 5 | | 1993 | 3 | 3 | 6 | | 1994 | 4 | 1 | 5 | | 1995 | 0 | 2 | 2 | | 1996 | 1 | 1 | 2 | | 1997 | 1 | 4 | 5 | | 1998 | 1 | 2 | 3 | | 1999 | 3 | 0 | 3 | | 2000 | 1 | 1 | 2 | | 2001 | 3 | 7 | 10 | | 2002 | 3 | 6 | 9 | | 2003 | 2 | 3 | 5 | | 2004 | 4 | 3 | 7 | | 2005 | 3 | 3 | 6 | | 2006 | 2 | 4 | 6 | | 2007 | 1 | 5 | 6 | | 2008 | 4 | 5 | 9 | | 2009 | 4 | 3 | 7 | | 2010 | 2 | 5 | 7 | | 2011 | 0 | 2 | 2 | | 2012 | 2 | 3 | 5 | | 2013 | 3 | 1 | 4 | | 2014 | 0 | 3 | 3 | | 2015 | 2 | 1 | 3 | | 2016 | 4 | 3 | 7 | | 2018 | 3 | 2 | 5 | | 2019 | 1 | 1 | 2 | | 2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Thymus Gland" by people in Profiles.
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Harsha Krovi S, Zhang J, Michaels-Foster MJ, Brunetti T, Loh L, Scott-Browne J, Gapin L. Thymic iNKT single cell analyses unmask the common developmental program of mouse innate T cells. Nat Commun. 2020 12 07; 11(1):6238.
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Wells KL, Miller CN, Gschwind AR, Wei W, Phipps JD, Anderson MS, Steinmetz LM. Combined transient ablation and single-cell RNA-sequencing reveals the development of medullary thymic epithelial cells. Elife. 2020 11 23; 9.
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Bosticardo M, Yamazaki Y, Cowan J, Giardino G, Corsino C, Scalia G, Prencipe R, Ruffner M, Hill DA, Sakovich I, Yemialyanava I, Tam JS, Padem N, Elder ME, Sleasman JW, Perez E, Niebur H, Seroogy CM, Sharapova S, Gebbia J, Kleiner GI, Peake J, Abbott JK, Gelfand EW, Crestani E, Biggs C, Butte MJ, Hartog N, Hayward A, Chen K, Heimall J, Seeborg F, Bartnikas LM, Cooper MA, Pignata C, Bhandoola A, Notarangelo LD. Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis. Am J Hum Genet. 2019 09 05; 105(3):549-561.
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Wang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, Dai S. How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol. 2019 04 05; 4(34).
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Miller CN, Proekt I, von Moltke J, Wells KL, Rajpurkar AR, Wang H, Rattay K, Khan IS, Metzger TC, Pollack JL, Fries AC, Lwin WW, Wigton EJ, Parent AV, Kyewski B, Erle DJ, Hogquist KA, Steinmetz LM, Locksley RM, Anderson MS. Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development. Nature. 2018 07; 559(7715):627-631.
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Marrack P. Where Have All the Flowers Gone? J Immunol. 2018 07 01; 201(1):5-6.
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Thornton LM, Path EM, Nystrom GS, Venables BJ, Sellin Jeffries MK. Embryo-larval BDE-47 exposure causes decreased pathogen resistance in adult male fathead minnows (Pimephales promelas). Fish Shellfish Immunol. 2018 Sep; 80:80-87.
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Sundararaj S, Zhang J, Krovi SH, Bedel R, Tuttle KD, Veerapen N, Besra GS, Khandokar Y, Praveena T, Le Nours J, Matsuda JL, Rossjohn J, Gapin L. Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function. Proc Natl Acad Sci U S A. 2018 02 06; 115(6):E1204-E1213.
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Tuttle KD, Gapin L. Characterization of Thymic Development of Natural Killer T Cell Subsets by Multiparameter Flow Cytometry. Methods Mol Biol. 2018; 1799:121-133.
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Langgartner D, Peterlik D, Foertsch S, Füchsl AM, Brokmann P, Flor PJ, Shen Z, Fox JG, Uschold-Schmidt N, Lowry CA, Reber SO. Individual differences in stress vulnerability: The role of gut pathobionts in stress-induced colitis. Brain Behav Immun. 2017 Aug; 64:23-32.
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