 Thymus Gland
"Thymus Gland" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A single, unpaired primary lymphoid organ situated in the MEDIASTINUM, extending superiorly into the neck to the lower edge of the THYROID GLAND and inferiorly to the fourth costal cartilage. It is necessary for normal development of immunologic function early in life. By puberty, it begins to involute and much of the tissue is replaced by fat.
| Descriptor ID |
D013950
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| MeSH Number(s) |
A10.549.750 A15.382.520.604.750
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| Concept/Terms |
Thymus Gland- Thymus Gland
- Gland, Thymus
- Glands, Thymus
- Thymus Glands
- Thymus
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Below are MeSH descriptors whose meaning is more general than "Thymus Gland".
Below are MeSH descriptors whose meaning is more specific than "Thymus Gland".
This graph shows the total number of publications written about "Thymus Gland" by people in this website by year, and whether "Thymus Gland" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 5 | 1 | 6 | | 1995 | 1 | 2 | 3 | | 1996 | 2 | 1 | 3 | | 1997 | 1 | 4 | 5 | | 1998 | 1 | 2 | 3 | | 1999 | 3 | 1 | 4 | | 2000 | 1 | 2 | 3 | | 2001 | 2 | 7 | 9 | | 2002 | 2 | 3 | 5 | | 2003 | 2 | 4 | 6 | | 2004 | 4 | 3 | 7 | | 2005 | 4 | 3 | 7 | | 2006 | 2 | 3 | 5 | | 2007 | 1 | 6 | 7 | | 2008 | 4 | 5 | 9 | | 2009 | 3 | 3 | 6 | | 2010 | 2 | 2 | 4 | | 2011 | 0 | 3 | 3 | | 2012 | 2 | 3 | 5 | | 2013 | 2 | 1 | 3 | | 2014 | 0 | 3 | 3 | | 2015 | 2 | 1 | 3 | | 2016 | 2 | 4 | 6 | | 2018 | 3 | 2 | 5 | | 2019 | 2 | 2 | 4 | | 2020 | 2 | 0 | 2 | | 2021 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 | | 2023 | 1 | 1 | 2 |
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Below are the most recent publications written about "Thymus Gland" by people in Profiles.
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Palmer WH, Leaton LA, Campos Codo A, Crute B, Roest J, Zhu S, Petersen J, Tobin RP, Hume PS, Stone M, van Bokhoven A, Gerich ME, McCarter MD, Zhu Y, Janssen WJ, Vivian JP, Trowsdale J, Getahun A, Rossjohn J, Cambier J, Loh L, Norman PJ. Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cells. Sci Immunol. 2023 06 30; 8(84):eade5343.
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Ramos SA, Armitage LH, Morton JJ, Alzofon N, Handler D, Kelly G, Homann D, Jimeno A, Russ HA. Generation of functional thymic organoids from human pluripotent stem cells. Stem Cell Reports. 2023 04 11; 18(4):829-840.
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Dvorak CC, Haddad E, Heimall J, Dunn E, Buckley RH, Kohn DB, Cowan MJ, Pai SY, Griffith LM, Cuvelier GDE, Eissa H, Shah AJ, O'Reilly RJ, Pulsipher MA, Wright NAM, Abraham RS, Satter LF, Notarangelo LD, Puck JM. The diagnosis of severe combined immunodeficiency (SCID): The Primary Immune Deficiency Treatment Consortium (PIDTC) 2022 Definitions. J Allergy Clin Immunol. 2023 02; 151(2):539-546.
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Szwarc MM, Hai L, Maurya VK, Rajapakshe K, Perera D, Ittmann MM, Mo Q, Lin Y, Bettini ML, Coarfa C, Lydon JP. Histopathologic and transcriptomic phenotypes of a conditional RANKL transgenic mouse thymus. Cytokine. 2022 12; 160:156022.
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Ramos SA, Morton JJ, Yadav P, Reed B, Alizadeh SI, Shilleh AH, Perrenoud L, Jaggers J, Kappler J, Jimeno A, Russ HA. Generation of functional human thymic cells from induced pluripotent stem cells. J Allergy Clin Immunol. 2022 02; 149(2):767-781.e6.
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Harsha Krovi S, Zhang J, Michaels-Foster MJ, Brunetti T, Loh L, Scott-Browne J, Gapin L. Thymic iNKT single cell analyses unmask the common developmental program of mouse innate T cells. Nat Commun. 2020 12 07; 11(1):6238.
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Wells KL, Miller CN, Gschwind AR, Wei W, Phipps JD, Anderson MS, Steinmetz LM. Combined transient ablation and single-cell RNA-sequencing reveals the development of medullary thymic epithelial cells. Elife. 2020 11 23; 9.
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Marrack P. Obsessive-Compulsive Behavior Isn't Necessarily a Bad Thing. Annu Rev Immunol. 2020 04 26; 38:1-21.
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Bruns LA, Isbey S, Tanverdi M, Kane I. Late-Onset Vitamin K Deficiency Presenting as Scrotal Bruising and Mediastinal Mass. Pediatr Emerg Care. 2019 Oct; 35(10):e192-e193.
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Bosticardo M, Yamazaki Y, Cowan J, Giardino G, Corsino C, Scalia G, Prencipe R, Ruffner M, Hill DA, Sakovich I, Yemialyanava I, Tam JS, Padem N, Elder ME, Sleasman JW, Perez E, Niebur H, Seroogy CM, Sharapova S, Gebbia J, Kleiner GI, Peake J, Abbott JK, Gelfand EW, Crestani E, Biggs C, Butte MJ, Hartog N, Hayward A, Chen K, Heimall J, Seeborg F, Bartnikas LM, Cooper MA, Pignata C, Bhandoola A, Notarangelo LD. Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis. Am J Hum Genet. 2019 09 05; 105(3):549-561.
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