Transcription Factors, General
"Transcription Factors, General" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transcription factors that form transcription initiation complexes on DNA, bind to specific DNA-DIRECTED RNA POLYMERASES and are required to initiate transcription. Although their binding may be localized to distinct sequence and structural motifs within the DNA they are considered non-specific with regard to the specific gene being transcribed.
Descriptor ID |
D035165
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MeSH Number(s) |
D12.776.260.775 D12.776.930.930
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transcription Factors, General".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factors, General".
This graph shows the total number of publications written about "Transcription Factors, General" by people in this website by year, and whether "Transcription Factors, General" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 0 | 1 | 1 | 2010 | 0 | 1 | 1 | 2011 | 0 | 1 | 1 | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transcription Factors, General" by people in Profiles.
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Horn AE, Kugel JF, Goodrich JA. Single molecule microscopy reveals mechanistic insight into RNA polymerase II preinitiation complex assembly and transcriptional activity. Nucleic Acids Res. 2016 09 06; 44(15):7132-43.
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Jun SH, Reichlen MJ, Tajiri M, Murakami KS. Archaeal RNA polymerase and transcription regulation. Crit Rev Biochem Mol Biol. 2011 Feb; 46(1):27-40.
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Gomes NP, Espinosa JM. Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding. Genes Dev. 2010 May 15; 24(10):1022-34.
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Black JC, Choi JE, Lombardo SR, Carey M. A mechanism for coordinating chromatin modification and preinitiation complex assembly. Mol Cell. 2006 Sep 15; 23(6):809-18.
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